A positive feedback mechanism in the transcriptional activation of Apaf-1 by p53 and the coactivator Zac-1. (Q40744476)

23 September 2017

A positive feedback mechanism in the transcriptional activation of Apaf-1 by p53 and the coactivator Zac-1. (English)

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23 September 2017

6

David Givol

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23 September 2017

7

Gideon Rechavi

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23 September 2017

5

Ninette Amariglio

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23 September 2017

4

Amos Toren

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Janakiraman Krishnamurthy

23 September 2017

series ordinal

2

object named as

Janakiraman Krishnamurthy

1 reference

23 September 2017

Galit Rozenfeld-Granot

series ordinal

1

object named as

Galit Rozenfeld-Granot

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23 September 2017

Karuppiah Kannan

3

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23 September 2017

language of work or name

English

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publication date

1 February 2002

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23 September 2017

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23 September 2017

21

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23 September 2017

10

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23 September 2017

1469-1476

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205218

23 September 2017

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cites work

Apoptotic molecular machinery: vastly increased complexity in vertebrates revealed by genome comparisons

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A novel imprinted gene, HYMAI, is located within an imprinted domain on human chromosome 6 containing ZAC.

21 January 2018

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Mechanisms of p53-mediated apoptosis

21 January 2018

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Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development

21 January 2018

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Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

21 January 2018

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Definition of a consensus binding site for p53

21 January 2018

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21 January 2018

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BCL-2 family members and the mitochondria in apoptosis

21 January 2018

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Mouse Zac1, a transcriptional coactivator and repressor for nuclear receptors

21 January 2018

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Enhancement of p53-dependent gene activation by the transcriptional coactivator Zac1

21 January 2018

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Apaf-1 protein deficiency confers resistance to cytochrome c-dependent apoptosis in human leukemic cells

21 January 2018

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A transactivation-deficient mouse model provides insights into Trp53 regulation and function

21 January 2018

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DNA microarrays identification of primary and secondary target genes regulated by p53.

21 January 2018

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DNA microarray analysis of genes involved in p53 mediated apoptosis: activation of Apaf-1.

21 January 2018

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Bcl-2-family proteins: the role of the BH3 domain in apoptosis.

21 January 2018

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p53, the cellular gatekeeper for growth and division

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A novel form of Epstein-Barr virus latency in normal B cells in vivo

21 January 2018

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PUMA, a novel proapoptotic gene, is induced by p53

21 January 2018

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Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

21 January 2018

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Dysregulation of apoptosis in cancer

21 January 2018

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ASPP proteins specifically stimulate the apoptotic function of p53

21 January 2018

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Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.

21 January 2018

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Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

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Regulation of apoptosis and cell cycle arrest by Zac1, a novel zinc finger protein expressed in the pituitary gland and the brain

21 January 2018

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One mechanism for cell type-specific regulation of the bax promoter by the tumor suppressor p53 is dictated by the p53 response element

21 January 2018

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hZAC encodes a zinc finger protein with antiproliferative properties and maps to a chromosomal region frequently lost in cancer

21 January 2018

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Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

21 January 2018

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Apaf1 is required for mitochondrial pathways of apoptosis and brain development

21 January 2018

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PUMA induces the rapid apoptosis of colorectal cancer cells

21 January 2018

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An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

21 January 2018

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Loss of expression of the candidate tumor suppressor gene ZAC in breast cancer cell lines and primary tumors

21 January 2018

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Apaf-1 is a transcriptional target for E2F and p53

21 January 2018

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Cytochrome c promotes caspase-9 activation by inducing nucleotide binding to Apaf-1

21 January 2018

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205218

inferred from DOI database lookup

7 January 2021

based on heuristic

Characterization of the methylation-sensitive promoter of the imprinted ZAC gene supports its role in transient neonatal diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205218

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1205218

1 reference

Dimensions Publication ID

23 September 2017

0 references

1 reference