Preferential methylation of unmethylated DNA by Mammalian de novo DNA methyltransferase Dnmt3a. (Q40753457)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11821381%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

title

Preferential methylation of unmethylated DNA by Mammalian de novo DNA methyltransferase Dnmt3a (English)

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6 December 2019

2

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6 December 2019

author name string

Tomoki Yokochi

series ordinal

1

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6 December 2019

language of work or name

English

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publication date

30 January 2002

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Journal of Biological Chemistry

6 December 2019

published in

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6 December 2019

volume

277

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6 December 2019

issue

14

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6 December 2019

page(s)

11735-11745

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Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

6 December 2019

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DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

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DNA hypomethylation leads to elevated mutation rates

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Loss of methylation activates Xist in somatic but not in embryonic cells

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Genomic imprinting: parental influence on the genome

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Cytosine methylation and the ecology of intragenomic parasites

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CpG-rich islands and the function of DNA methylation

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DNA hypermethylation in tumorigenesis: epigenetics joins genetics

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The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors

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A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei

21 January 2018

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Multiple domains are involved in the targeting of the mouse DNA methyltransferase to the DNA replication foci

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Recombinant human DNA (cytosine-5) methyltransferase. I. Expression, purification, and comparison of de novo and maintenance methylation

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Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases

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DNA methyltransferase Dnmt1 associates with histone deacetylase activity

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DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

21 January 2018

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DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

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Human DNA-(Cytosine-5) Methyltransferase-PCNA Complex as a Target for p21WAF1

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Recombinant Human DNA (Cytosine-5) Methyltransferase

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HhaI methyltransferase flips its target base out of the DNA helix

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Mechanism of human methyl-directed DNA methyltransferase and the fidelity of cytosine methylation

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Mammalian (cytosine-5) methyltransferases cause genomic DNA methylation and lethality in Drosophila.

21 January 2018

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Enzymatic properties of recombinant Dnmt3a DNA methyltransferase from mouse: the enzyme modifies DNA in a non-processive manner and also methylates non-CpG [correction of non-CpA] sites

21 January 2018

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Murine DNA cytosine-C5 methyltransferase: pre-steady- and steady-state kinetic analysis with regulatory DNA sequences

21 January 2018

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Purification and characterization of recombinant baculovirus-expressed mouse DNA methyltransferase

21 January 2018

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Baculovirus-mediated expression and characterization of the full-length murine DNA methyltransferase

21 January 2018

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Recombinant human DNA (cytosine-5) methyltransferase. II. Steady-state kinetics reveal allosteric activation by methylated dna.

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Bacteriophage T4 Dam DNA-[N6-adenine]methyltransferase. Kinetic evidence for a catalytically essential conformational change in the ternary complex

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription

21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M106590200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11821381%20AND%20SRC:MED&resulttype=core&format=json

release_36yn4ucd4jdi3bn4lj5vlwwbbm

6 December 2019

Fatcat ID

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mapped directly with Wikidata item

24 November 2022

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