Cellular responses to murine CD40 in a mouse B cell line may be TRAF dependent or independent (Q40761285)

23 September 2017

Cellular responses to murine CD40 in a mouse B cell line may be TRAF dependent or independent (English)

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23 September 2017

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Eric Manning

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23 September 2017

Steven S Pullen

2

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23 September 2017

Donald J Souza

3

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23 September 2017

Marilyn Kehry

4

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23 September 2017

Randolph J Noelle

5

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23 September 2017

language of work or name

English

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publication date

1 January 2002

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European Journal of Immunology

23 September 2017

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23 September 2017

32

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23 September 2017

1

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23 September 2017

39-49

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In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39.

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Memory B cell development but not germinal center formation is impaired by in vivo blockade of CD40-CD40 ligand interaction

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TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40

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Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region

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TRAF5, a novel tumor necrosis factor receptor-associated factor family protein, mediates CD40 signaling

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CD40-tumor necrosis factor receptor-associated factor (TRAF) interactions: regulation of CD40 signaling through multiple TRAF binding sites and TRAF hetero-oligomerization

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CD40-mediated regulation of immune responses by TRAF-dependent and TRAF-independent signaling mechanisms.

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TRAF5, an activator of NF-kappaB and putative signal transducer for the lymphotoxin-beta receptor

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Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2

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CD40 signaling through tumor necrosis factor receptor-associated factors (TRAFs). Binding site specificity and activation of downstream pathways by distinct TRAFs

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Characterization of the roles of TNF receptor-associated factor 6 in CD40-mediated B lymphocyte effector functions

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Differential requirements for tumor necrosis factor receptor-associated factor family proteins in CD40-mediated induction of NF-kappaB and Jun N-terminal kinase activation.

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Activation and regulation of the IkappaB kinase in human B cells by CD40 signaling

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Selective activation of c-Jun kinase mitogen-activated protein kinase by CD40 on human B cells

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High-affinity interactions of tumor necrosis factor receptor-associated factors (TRAFs) and CD40 require TRAF trimerization and CD40 multimerization

21 January 2018

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TRAF2 deficiency results in hyperactivity of certain TNFR1 signals and impairment of CD40-mediated responses.

21 January 2018

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TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

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Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice

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Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses.

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Identification of the intracytoplasmic region essential for signal transduction through a B cell activation molecule, CD40.

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Tumor necrosis factor alpha is an autocrine growth factor for normal human B cells

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Recruitment of CD40 and tumor necrosis factor receptor-associated factors 2 and 3 to membrane microdomains during CD40 signaling

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CD40 signaling in human dendritic cells is initiated within membrane rafts

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Protein and lipid requirements for endocytosis

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Caveolin-1 associates with TRAF2 to form a complex that is recruited to tumor necrosis factor receptors

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Endocytosis and mitogenic signaling

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Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages.

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A vector driving the expression of foreign cDNAs in the MHC class II-positive cells of transgenic mice

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TRAF2 is essential for JNK but not NF-kappaB activation and regulates lymphocyte proliferation and survival

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Jak3 is associated with CD40 and is critical for CD40 induction of gene expression in B cells

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10.1002/1521-4141(200201)32:1<39::AID-IMMU39>3.0.CO;2-Y

21 January 2018

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23 September 2017

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