The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change (Q40761363)

23 September 2017

The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change (English)

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23 September 2017

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2

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23 September 2017

Yamaguchi H

1

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23 September 2017

language of work or name

English

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publication date

1 November 2001

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23 September 2017

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23 September 2017

20

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23 September 2017

7779-7786

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23 September 2017

53

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1204984

23 September 2017

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cites work

Role of translocation in the activation and function of protein kinase B

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Molecular cloning and characterization of Bif-1. A novel Src homology 3 domain-containing protein that associates with Bax

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Cellular survival: a play in three Akts

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

PI3K: downstream AKTion blocks apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Regulated targeting of BAX to mitochondria.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Mitochondria and apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

BCL-2 family members and the mitochondria in apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Bax in murine thymus is a soluble monomeric protein that displays differential detergent-induced conformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Two distinct interleukin-3-mediated signal pathways, Ras-NFIL3 (E4BP4) and Bcl-xL, regulate the survival of murine pro-B lymphocytes

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

In bone marrow derived Baf-3 cells, inhibition of apoptosis by IL-3 is mediated by two independent pathways.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Bcl-2 inhibits a Fas-induced conformational change in the Bax N terminus and Bax mitochondrial translocation.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Conformation of the Bax C-terminus regulates subcellular location and cell death

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Protein translocation in apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Social controls on cell survival and cell death

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

IL-3 signaling and the role of Src kinases, JAKs and STATs: a covert liaison unveiled

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

21 January 2018

Bcl-2 family proteins

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Interleukin 3-dependent survival by the Akt protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

BID: a novel BH3 domain-only death agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Movement of Bax from the cytosol to mitochondria during apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Akt regulates cell survival and apoptosis at a postmitochondrial level

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

21 January 2018

A Bad kinase makes good

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Akt is more than just a Bad kinase

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

Nonionic detergents induce dimerization among members of the Bcl-2 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204984

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1204984

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Dimensions Publication ID

23 September 2017

1027899748

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Fatcat ID

release_ondlygmj5vcgvjny25qzfyoa3a

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ondlygmj5vcgvjny25qzfyoa3a

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference