A critical role for Pin2/TRF1 in ATM-dependent regulation. Inhibition of Pin2/TRF1 function complements telomere shortening, radiosensitivity, and the G(2)/M checkpoint defect of ataxia-telangiectasia cells (Q40763320)

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English	A critical role for Pin2/TRF1 in ATM-dependent regulation. Inhibition of Pin2/TRF1 function complements telomere shortening, radiosensitivity, and the G(2)/M checkpoint defect of ataxia-telangiectasia cells	scientific article

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scholarly article

1 reference

Europe PubMed Central

23 September 2017

A critical role for Pin2/TRF1 in ATM-dependent regulation. Inhibition of Pin2/TRF1 function complements telomere shortening, radiosensitivity, and the G(2)/M checkpoint defect of ataxia-telangiectasia cells (English)

1 reference

Europe PubMed Central

23 September 2017

author name string

Shuji Kishi

1

1 reference

Europe PubMed Central

23 September 2017

Kun Ping Lu

2

1 reference

Europe PubMed Central

23 September 2017

language of work or name

0 references

publication date

13 December 2001

1 reference

Europe PubMed Central

23 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

23 September 2017

277

1 reference

Europe PubMed Central

23 September 2017

9

1 reference

Europe PubMed Central

23 September 2017

7420-7429

1 reference

Europe PubMed Central

23 September 2017

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

The genetic defect in ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Cell cycle checkpoint signaling through the ATM and ATR kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Characterization of RAD9 of Saccharomyces cerevisiae and evidence that its function acts posttranslationally in cell cycle arrest after DNA damage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Feedback control of mitosis in budding yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Cell cycle control and cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Interaction between ATM protein and c-Abl in response to DNA damage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Enhanced phosphorylation of p53 by ATM in response to DNA damage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

ATM associates with and phosphorylates p53: mapping the region of interaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Substrate specificities and identification of putative substrates of ATM kinase family members

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Atm-deficient mice: a paradigm of ataxia telangiectasia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Dual roles of ATM in the cellular response to radiation and in cell growth control.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Pleiotropic defects in ataxia-telangiectasia protein-deficient mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Detection of induced mitotic chromosome loss in Saccharomyces cerevisiae--an interlaboratory study

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Reduced telomere length in ataxia-telangiectasia fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Fragments of ATM which have dominant-negative or complementing activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Altered telomere nuclear matrix interactions and nucleosomal periodicity in ataxia telangiectasia cells before and after ionizing radiation treatment

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Identification of yeast mutants with altered telomere structure

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

The yeast TEL1 gene partially substitutes for human ATM in suppressing hyperrecombination, radiation-induced apoptosis and telomere shortening in A-T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Characterization of ataxia telangiectasia fibroblasts with extended life-span through telomerase expression.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Altering telomere structure allows telomerase to act in yeast lacking ATM kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

A human telomeric protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

A human peptidyl-prolyl isomerase essential for regulation of mitosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Characterization and cell cycle regulation of the related human telomeric proteins Pin2 and TRF1 suggest a role in mitosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Organization and expression of human telomere repeat binding factor genes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Control of telomere length by the human telomeric protein TRF1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Tankyrase, a poly(ADP-ribose) polymerase at human telomeres

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

TIN2, a new regulator of telomere length in human cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Critical role for the EB1 and APC interaction in the regulation of microtubule polymerization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

A specific interaction between the telomeric protein Pin2/TRF1 and the mitotic spindle.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Telomeric protein Pin2/TRF1 induces mitotic entry and apoptosis in cells with short telomeres and is down-regulated in human breast tumors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Block in anaphase chromosome separation caused by a telomerase template mutation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Recombinant ATM protein complements the cellular A-T phenotype

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Human cDNA clones that modify radiomimetic sensitivity of ataxia-telangiectasia (group A) cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Evidence for a NIMA-like mitotic pathway in vertebrate cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Cell death, chromosome damage and mitotic delay in normal human, ataxia telangiectasia and retinoblastoma fibroblasts after x-irradiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Predominance of null mutations in ataxia-telangiectasia.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Identification of ataxia telangiectasia heterozygotes, a cancer prone population

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Chk1 complements the G2/M checkpoint defect and radiosensitivity of ataxia-telangiectasia cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Radiosensitivity in ataxia-telangiectasia: a new explanation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Effect of ionizing radiation on DNA synthesis in ataxia telangiectasia cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Telomerase activity in human ovarian carcinoma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Restoration of telomeres in human papillomavirus-immortalized human anogenital epithelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

TRF1 is a dimer and bends telomeric DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

How proteolysis drives the cell cycle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Chromosome end associations, telomeres and telomerase activity in ataxia telangiectasia cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Accelerated telomere shortening in ataxia telangiectasia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Ataxia telangiectasia: a human mutation with abnormal radiation sensitivity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Radiation-Induced Division Delay in Synchronized Chinese Hamster Ovary Cells in Monolayer Culture

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

DNA synthesis and cell cycle progression of synchronized L-cells after irradiation in various phases of the cell cycle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Influence of ATM function on telomere metabolism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Phosphorylation-dependent prolyl isomerization: a novel cell cycle regulatory mechanism.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Loss of a yeast telomere: arrest, recovery, and chromosome loss.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Ataxia telangiectasia. Neoplasia, untoward response to x-irradiation, and tuberous sclerosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Radiation reaction in ataxia telangiectasia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

Defect in multiple cell cycle checkpoints in ataxia-telangiectasia postirradiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111365200

21 January 2018

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10.1074/JBC.M111365200

1 reference

Europe PubMed Central

23 September 2017

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Europe PubMed Central

23 September 2017

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