DNA damage invokes mismatch repair-dependent cyclin D1 attenuation and retinoblastoma signaling pathways to inhibit CDK2. (Q40765943)

23 September 2017

DNA damage invokes mismatch repair-dependent cyclin D1 attenuation and retinoblastoma signaling pathways to inhibit CDK2. (English)

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23 September 2017

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Zhengdao Lan

1

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23 September 2017

Zvjezdana Sever-Chroneos

2

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23 September 2017

Matthew W Strobeck

3

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23 September 2017

Chi-Hyun Park

4

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23 September 2017

R Baskaran

5

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23 September 2017

Winfried Edelmann

6

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23 September 2017

Gustavo Leone

7

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23 September 2017

Erik S Knudsen

8

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23 September 2017

language of work or name

English

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publication date

28 November 2001

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Journal of Biological Chemistry

23 September 2017

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23 September 2017

277

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23 September 2017

10

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23 September 2017

8372-8381

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Cell cycle checkpoints: preventing an identity crisis

23 September 2017

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https://api.crossref.org/works/10.1074%2FJBC.M108906200

Pathways governing G1/S transition and their response to DNA damage

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M108906200

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M108906200

Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M108906200

Control of pRB phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M108906200

Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M108906200

The regulation of E2F by pRB-family proteins

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M108906200

Role of the Rb/E2F pathway in cell growth control

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M108906200

p21 is a critical CDK2 regulator essential for proliferation control in Rb-deficient cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108906200

pRB plays an essential role in cell cycle arrest induced by DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108906200

RB-dependent S-phase response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108906200

Mismatch repair: mechanisms and relationship to cancer susceptibility

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M108906200

DNA chaperones: a solution to a persistence problem?

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M108906200

Identification of mismatch repair genes and their role in the development of cancer

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M108906200

Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M108906200

Cisplatin and adriamycin resistance are associated with MutLalpha and mismatch repair deficiency in an ovarian tumor cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108906200

Mammalian DNA mismatch repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108906200

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108906200

Inhibition of DNA synthesis by RB: effects on G1/S transition and S-phase progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108906200

Dual mechanisms for the inhibition of E2F binding to RB by cyclin-dependent kinase-mediated RB phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108906200

Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108906200

Induction of JNK and c-Abl signalling by cisplatin and oxaliplatin in mismatch repair-proficient and -deficient cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108906200

hMLH1 expression and cellular responses of ovarian tumour cells to treatment with cytotoxic anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108906200

Msh2 status modulates both apoptosis and mutation frequency in the murine small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108906200

Eukaryotic DNA mismatch repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108906200

CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108906200

Cyclin D1 is dispensable for G1 control in retinoblastoma gene-deficient cells independently of cdk4 activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108906200

The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108906200

Requirement of cyclin E-Cdk2 inhibition in p16(INK4a)-mediated growth suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108906200

Induced expression of p16(INK4a) inhibits both CDK4- and CDK2-associated kinase activity by reassortment of cyclin-CDK-inhibitor complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108906200

Lycopene inhibition of cell cycle progression in breast and endometrial cancer cells is associated with reduction in cyclin D levels and retention of p27(Kip1) in the cyclin E-cdk2 complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108906200

Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27(Kip1) and p21(Cip1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108906200

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108906200

Distinct Initiation and Maintenance Mechanisms Cooperate to Induce G1 Cell Cycle Arrest in Response to DNA Damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108906200

DNA damage and checkpoint pathways: molecular anatomy and interactions with repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108906200

Regulation of DNA-dependent protein kinase activity by ionizing radiation-activated abl kinase is an ATM-dependent process

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108906200

21 January 2018

Identifiers

DOI

10.1074/JBC.M108906200

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23 September 2017

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