RET/PTC1 oncogene signaling in PC Cl 3 thyroid cells requires the small GTP-binding protein Rho. (Q40769254)

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3 December 2019

title

RET/PTC1 oncogene signaling in PC Cl 3 thyroid cells requires the small GTP-binding protein Rho (English)

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3 December 2019

9

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3 December 2019

Maria Vittoria Barone

1

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3 December 2019

Rosa Marina Melillo

3

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Maria Domenica Castellone

3 December 2019

7

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3 December 2019

author name string

L Sepe

2

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3 December 2019

A Mineo

4

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3 December 2019

G Santelli

5

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3 December 2019

C Monaco

6

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3 December 2019

D Tramontano

8

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3 December 2019

M Santoro

10

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3 December 2019

language of work or name

English

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publication date

1 October 2001

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3 December 2019

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3 December 2019

volume

20

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3 December 2019

issue

48

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3 December 2019

page(s)

6973-6982

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1204886

3 December 2019

exact match

0 references

cites work

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GDNF family neurotrophic factor signaling: four masters, one servant?

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Grb2 binding to the different isoforms of Ret tyrosine kinase.

21 January 2018

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Identification of Shc docking site on Ret tyrosine kinase

21 January 2018

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A mutation at tyrosine 1062 in MEN2A-Ret and MEN2B-Ret impairs their transforming activity and association with shc adaptor proteins

21 January 2018

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Ras and Rho GTPases: a family reunion

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Myc but not Fos rescue of PDGF signalling block caused by kinase-inactive Src.

21 January 2018

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Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase.

21 January 2018

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The full oncogenic activity of Ret/ptc2 depends on tyrosine 539, a docking site for phospholipase Cgamma

21 January 2018

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The Dbl family of oncogenes

21 January 2018

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Signalling of the Ret receptor tyrosine kinase through the c-Jun NH2-terminal protein kinases (JNKS): evidence for a divergence of the ERKs and JNKs pathways induced by Ret.

21 January 2018

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Genomic analysis of metastasis reveals an essential role for RhoC

21 January 2018

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The GTPase rho controls a p53-dependent survival checkpoint during thymopoiesis

21 January 2018

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Shc and Enigma are both required for mitogenic signaling by Ret/ptc2.

21 January 2018

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High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas

21 January 2018

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One- and two-step transformations of rat thyroid epithelial cells by retroviral oncogenes

21 January 2018

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PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas

21 January 2018

1 reference

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Characterization of intracellular signals via tyrosine 1062 in RET activated by glial cell line-derived neurotrophic factor

21 January 2018

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cDNA cloning and characterization of ret activated in a human papillary thyroid carcinoma cell line

21 January 2018

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The RET proto-oncogene in human cancers

21 January 2018

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21 January 2018

Signaling to Rho GTPases

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Rho family GTPases and neuronal growth cone remodelling: relationship between increased complexity induced by Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid

21 January 2018

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The insulin receptor substrate (IRS)-1 recruits phosphatidylinositol 3-kinase to Ret: evidence for a competition between Shc and IRS-1 for the binding to Ret.

21 January 2018

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Docking protein FRS2 links the protein tyrosine kinase RET and its oncogenic forms with the mitogen-activated protein kinase signaling cascade

21 January 2018

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A balance of signaling by Rho family small GTPases RhoA, Rac1 and Cdc42 coordinates cytoskeletal morphology but not cell survival

21 January 2018

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Rho, rac and cdc42 GTPases: regulators of actin structures, cell adhesion and motility

21 January 2018

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Direct association between the Ret receptor tyrosine kinase and the Src homology 2-containing adapter protein Grb7

21 January 2018

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The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

21 January 2018

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

21 January 2018

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Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

21 January 2018

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Microinjection of catalytic subunit of cyclic AMP-dependent protein kinase triggers acute morphological changes in thyroid epithelial cells.

21 January 2018

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Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B

21 January 2018

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Molecular defects in thyroid carcinomas: Role of the RET oncogene in thyroid neoplastic transformation

21 January 2018

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EPS8 and E3B1 transduce signals from Ras to Rac

21 January 2018

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Signaling from Ras to Rac and beyond: not just a matter of GEFs

21 January 2018

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Transforming ability of MEN2A-RET requires activation of the phosphatidylinositol 3-kinase/AKT signaling pathway.

21 January 2018

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Rho GTPases and signaling networks

21 January 2018

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Rho family proteins and Ras transformation: the RHOad less traveled gets congested.

21 January 2018

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RET alternate splicing influences the interaction of activated RET with the SH2 and PTB domains of Shc, and the SH2 domain of Grb2

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Papillary and follicular thyroid carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204886

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1204886

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11704822%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

3 December 2019

0 references

1 reference