A new role for the p85-phosphatidylinositol 3-kinase regulatory subunit linking FRAP to p70 S6 kinase activation. (Q40771721)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11684675%20AND%20SRC:MED&resulttype=core&format=json

2 December 2019

title

A new role for the p85-phosphatidylinositol 3-kinase regulatory subunit linking FRAP to p70 S6 kinase activation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11684675%20AND%20SRC:MED&resulttype=core&format=json

2 December 2019

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11684675%20AND%20SRC:MED&resulttype=core&format=json

2 December 2019

Concepcion Jimenez

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11684675%20AND%20SRC:MED&resulttype=core&format=json

2 December 2019

Nicholas A Pullen

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11684675%20AND%20SRC:MED&resulttype=core&format=json

2 December 2019

Ana C. Carrera

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11684675%20AND%20SRC:MED&resulttype=core&format=json

2 December 2019

author name string

Ana Gonzalez-Garcia

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11684675%20AND%20SRC:MED&resulttype=core&format=json

2 December 2019

Elia Garrido

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11684675%20AND%20SRC:MED&resulttype=core&format=json

2 December 2019

Carmen Hernandez

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11684675%20AND%20SRC:MED&resulttype=core&format=json

2 December 2019

Beatriz Alvarez

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11684675%20AND%20SRC:MED&resulttype=core&format=json

2 December 2019

language of work or name

English

0 references

publication date

29 October 2001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11684675%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

2 December 2019

number of pages

9

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11684675%20AND%20SRC:MED&resulttype=core&format=json

2 December 2019

volume

277

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11684675%20AND%20SRC:MED&resulttype=core&format=json

2 December 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11684675%20AND%20SRC:MED&resulttype=core&format=json

2 December 2019

page(s)

1500-1508

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11684675%20AND%20SRC:MED&resulttype=core&format=json

Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

2 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

An encore for ribosome biogenesis in the control of cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Drosophila S6 kinase: a regulator of cell size

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

The modular phosphorylation and activation of p70s6k.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Phosphorylation and activation of p70s6k by PDK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Identification of the NIMA family kinases NEK6/7 as regulators of the p70 ribosomal S6 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Immunopurified mammalian target of rapamycin phosphorylates and activates p70 S6 kinase alpha in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycinassociated protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Dual requirement for a newly identified phosphorylation site in p70s6k

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Constitutive activation of S6 kinase by deletion of amino-terminal autoinhibitory and rapamycin sensitivity domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Signaling by distinct classes of phosphoinositide 3-kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

21 January 2018

Phosphoinositide kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

The activation of phosphatidylinositol 3-kinase by Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Identification and characterization of a new oncogene derived from the regulatory subunit of phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Multiple independent inputs are required for activation of the p70 S6 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/Rho-dependent effector pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Regulation of the p85/p110 phosphatidylinositol 3'-kinase: stabilization and inhibition of the p110alpha catalytic subunit by the p85 regulatory subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Purification and properties of mitogen-activated S6 kinase from rat liver and 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Protein kinase B localization and activation differentially affect S6 kinase 1 activity and eukaryotic translation initiation factor 4E-binding protein 1 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

p70 S6 kinase is regulated by protein kinase Czeta and participates in a phosphoinositide 3-kinase-regulated signalling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Protein phosphatase 1alpha is a Ras-activated Bad phosphatase that regulates interleukin-2 deprivation-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Protein phosphatase 2A is a critical regulator of protein kinase C zeta signaling targeted by SV40 small t to promote cell growth and NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Differential regulation by calcium reveals distinct signaling requirements for the activation of Akt and p70S6k

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Atypical protein kinase Clambda binds and regulates p70 S6 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Protein kinase C-zeta as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. Potential role in glucose transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Molecular cloning and characterization of a novel p70 S6 kinase, p70 S6 kinase beta containing a proline-rich region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Characterization of S6K2, a novel kinase homologous to S6K1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Protein kinases: getting NEKed for S6K activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Evidence That 3-Phosphoinositide-dependent Protein Kinase-1 Mediates Phosphorylation of p70 S6 Kinasein Vivoat Thr-412 as well as Thr-252

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

p70s6k function is essential for G1 progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Phosphatidylinositol 3-kinase links the interleukin-2 receptor to protein kinase B and p70 S6 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Phosphatidyl-inositol 3-kinase: a key enzyme in diverse signalling processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200

Phosphatidylinositol (3,4,5)P3 interacts with SH2 domains and modulates PI 3-kinase association with tyrosine-phosphorylated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103808200