Senescent Vascular Smooth Muscle Cells Drive Inflammation Through an Interleukin-1α-Dependent Senescence-Associated Secretory Phenotype (Q40771854)

23 September 2017

Senescent Vascular Smooth Muscle Cells Drive Inflammation Through an Interleukin-1α-Dependent Senescence-Associated Secretory Phenotype (English)

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23 September 2017

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3

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14 June 2020

Murray Clarke

series ordinal

4

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14 June 2020

author name string

Sarah E Gardner

series ordinal

1

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14 June 2020

Melanie Humphry

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2

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14 June 2020

language of work or name

English

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publication date

2 July 2015

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Arteriosclerosis, Thrombosis, and Vascular Biology

23 September 2017

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14 June 2020

volume

35

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14 June 2020

issue

9

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14 June 2020

page(s)

1963-1974

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Immune effector mechanisms implicated in atherosclerosis: from mice to humans

14 June 2020

cites work

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A complex secretory program orchestrated by the inflammasome controls paracrine senescence

24 September 2017

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Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1α, controlling necrosis-induced sterile inflammation

24 September 2017

1 reference

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Inflammasome activation and IL-1β target IL-1α for secretion as opposed to surface expression

24 September 2017

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Lack of interleukin-1α or interleukin-1β inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice

24 September 2017

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A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen

24 September 2017

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Cell surface-bound IL-1alpha is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network

24 September 2017

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Interleukin-1 regulates multiple atherogenic mechanisms in response to fat feeding

24 September 2017

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Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

24 September 2017

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Experimental models investigating the inflammatory basis of atherosclerosis

24 September 2017

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Long-term interleukin-6 levels and subsequent risk of coronary heart disease: two new prospective studies and a systematic review

24 September 2017

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Identification of a key pathway required for the sterile inflammatory response triggered by dying cells

24 September 2017

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Vascular smooth muscle cell senescence in atherosclerosis

24 September 2017

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Innate and adaptive immunity in the pathogenesis of atherosclerosis

24 September 2017

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Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men.

24 September 2017

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Interleukin-6 exacerbates early atherosclerosis in mice

24 September 2017

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MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B.

24 September 2017

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A leukocyte homologue of the IL-8 receptor CXCR-2 mediates the accumulation of macrophages in atherosclerotic lesions of LDL receptor-deficient mice

24 September 2017

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Impact of interleukin-6 on plaque development and morphology in experimental atherosclerosis.

24 September 2017

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Macrophage inflammatory protein-1 alpha rapidly modulates its receptors and inhibits the anti-CD3 mAb-mediated proliferation of T lymphocytes

15 June 2018

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Identification and characterization of an inhibitor of haemopoietic stem cell proliferation.

15 June 2018

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Fatty acid-induced mitochondrial uncoupling elicits inflammasome-independent IL-1α and sterile vascular inflammation in atherosclerosis

15 June 2018

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Inflammasome activators induce interleukin-1α secretion via distinct pathways with differential requirement for the protease function of caspase-1.

19 August 2018

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Vascular smooth muscle cell apoptosis induces interleukin-1-directed inflammation: effects of hyperlipidemia-mediated inhibition of phagocytosis.

19 August 2018

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Vascular smooth muscle cells undergo telomere-based senescence in human atherosclerosis: effects of telomerase and oxidative stress.

19 August 2018

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Interleukin-1 receptor signaling mediates atherosclerosis associated with bacterial exposure and/or a high-fat diet in a murine apolipoprotein E heterozygote model: pharmacotherapeutic implications

19 August 2018

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Risk of thrombosis in human atherosclerotic plaques: role of extracellular lipid, macrophage, and smooth muscle cell content

19 August 2018

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Role of Bone Marrow–Derived CC-Chemokine Receptor 5 in the Development of Atherosclerosis of Low-Density Lipoprotein Receptor Knockout Mice

19 August 2018

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Ccr5 But Not Ccr1 Deficiency Reduces Development of Diet-Induced Atherosclerosis in Mice

2 December 2018

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12 December 2020

Differential role and tissue specificity of interleukin-1α gene expression in atherogenesis and lipid metabolism

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12 December 2020

Inflammation and cardiovascular disease: role of the interleukin-1 receptor antagonist

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12 December 2020

IL-8 is an angiogenic factor in human coronary atherectomy tissue

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12 December 2020

Cellular senescence after single and repeated balloon catheter denudations of rabbit carotid arteries

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12 December 2020

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12 December 2020

Hemopoietic Stem Cell Inhibitor (SCI/MIP-1∝) Also Inhibits Clonogenic Epidermal Keratinocyte Proliferation

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12 December 2020

MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions

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12 December 2020

10.1161/ATVBAHA.115.305896

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26139463%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

1 reference

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14 June 2020

PubMed publication ID

26139463

1 reference