Deletion of N-terminal myristoylation site of HIV Nef abrogates both MHC-1 and CD4 down-regulation (Q40777827)

23 September 2017

Deletion of N-terminal myristoylation site of HIV Nef abrogates both MHC-1 and CD4 down-regulation (English)

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23 September 2017

Marjorie Robert-Guroff

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2

object named as

Robert-Guroff M

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23 September 2017

Peng B

1

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PubMed ID

11578695

23 September 2017

language of work or name

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1 October 2001

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23 September 2017

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23 September 2017

78

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23 September 2017

195-200

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23 September 2017

3

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Importance of the nef gene for maintenance of high virus loads and for development of AIDS

23 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2478%2801%2900250-4

7 January 2021

Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2478%2801%2900250-4

7 January 2021

Strong human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte activity in Sydney Blood Bank Cohort patients infected with nef-defective HIV type 1

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2478%2801%2900250-4

7 January 2021

Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2478%2801%2900250-4

7 January 2021

The role of Nef in the replication cycle of the human and simian immunodeficiency viruses

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2478%2801%2900250-4

7 January 2021

Human immunodeficiency virus (HIV) nef-specific cytotoxic T lymphocytes in noninfected heterosexual contact of HIV-infected patients

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2478%2801%2900250-4

7 January 2021

Simian immunodeficiency virus-specific CD8+ lymphocyte response in acutely infected rhesus monkeys.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2478%2801%2900250-4

7 January 2021

Early suppression of SIV replication by CD8+ nef-specific cytotoxic T cells in vaccinated macaques

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2478%2801%2900250-4

7 January 2021

The Nef protein of primate lentiviruses

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2478%2801%2900250-4

7 January 2021

HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2478%2801%2900250-4

7 January 2021

Analysis of human immunodeficiency virus type 1 nef gene sequences present in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2478%2801%2900250-4

7 January 2021

Dissociation of the CD4 downregulation and viral infectivity enhancement functions of human immunodeficiency virus type 1 Nef.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2478%2801%2900250-4

7 January 2021

Effect of myristoylation on p27nef subcellular distribution and suppression of HIV-LTR transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2478%2801%2900250-4

7 January 2021

Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2478%2801%2900250-4

7 January 2021

Nef 27, but not the Nef 25 isoform of human immunodeficiency virus-type 1 pNL4.3 down-regulates surface CD4 and IL-2R expression in peripheral blood mononuclear cells and transformed T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2478%2801%2900250-4

7 January 2021

Myristoylation-dependent binding of HIV-1 Nef to CD4.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2478%2801%2900250-4

7 January 2021

Nef-induced major histocompatibility complex class I down-regulation is functionally dissociated from its virion incorporation, enhancement of viral infectivity, and CD4 down-regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2478%2801%2900250-4

7 January 2021

Nef-induced CD4 and major histocompatibility complex class I (MHC-I) down-regulation are governed by distinct determinants: N-terminal alpha helix and proline repeat of Nef selectively regulate MHC-I trafficking

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2478%2801%2900250-4

7 January 2021

The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2478%2801%2900250-4

7 January 2021

Interactions between HIV1 Nef and vacuolar ATPase facilitate the internalization of CD4

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2478%2801%2900250-4

7 January 2021

Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2478%2801%2900250-4

7 January 2021

Mutational analysis of HIV-1 Nef: identification of two mutants that are temperature-sensitive for CD4 downregulation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2478%2801%2900250-4

7 January 2021

Immunopathogenesis of HIV infection

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2478%2801%2900250-4

7 January 2021

The selective downregulation of class I major histocompatibility complex proteins by HIV-1 protects HIV-infected cells from NK cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2478%2801%2900250-4

7 January 2021

Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2478%2801%2900250-4

7 January 2021

Targeting of HIV-1 antigens for rapid intracellular degradation enhances cytotoxic T lymphocyte (CTL) recognition and the induction of de novo CTL responses in vivo after immunization

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2478%2801%2900250-4

7 January 2021

10.1016/S0165-2478(01)00250-4

Identifiers

DOI

1 reference

23 September 2017

1 reference

PubMed ID

11578695