Alzheimer's disease-related overexpression of the cation-dependent mannose 6-phosphate receptor increases Abeta secretion: role for altered lysosomal hydrolase distribution in beta-amyloidogenesis (Q40781162)

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English	Alzheimer's disease-related overexpression of the cation-dependent mannose 6-phosphate receptor increases Abeta secretion: role for altered lysosomal hydrolase distribution in beta-amyloidogenesis	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

23 September 2017

Alzheimer's disease-related overexpression of the cation-dependent mannose 6-phosphate receptor increases Abeta secretion: role for altered lysosomal hydrolase distribution in beta-amyloidogenesis (English)

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23 September 2017

Alzheimer's disease

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Paul M Mathews

1

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23 September 2017

Carolyn B Guerra

2

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23 September 2017

Ying Jiang

3

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23 September 2017

Olivera M Grbovic

4

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23 September 2017

Benjamin H Kao

5

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23 September 2017

Stephen D Schmidt

6

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23 September 2017

Ravi Dinakar

7

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23 September 2017

Marc Mercken

8

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23 September 2017

Annette Hille-Rehfeld

9

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23 September 2017

Jack Rohrer

10

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23 September 2017

Pankaj Mehta

11

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23 September 2017

Anne M Cataldo

12

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23 September 2017

Ralph A Nixon

13

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23 September 2017

language of work or name

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publication date

10 September 2001

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23 September 2017

Journal of Biological Chemistry

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23 September 2017

277

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23 September 2017

7

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23 September 2017

5299-5307

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23 September 2017

The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease

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https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

The origins of Alzheimer disease: a is for amyloid.

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https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Maturation and pro-peptide cleavage of beta-secretase

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https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Phosphorylation regulates intracellular trafficking of beta-secretase

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https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Identification of beta-secretase-like activity using a mass spectrometry-based assay system

1 reference

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21 January 2018

Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutations

1 reference

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21 January 2018

Gene expression and cellular content of cathepsin D in Alzheimer's disease brain: evidence for early up-regulation of the endosomal-lysosomal system.

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https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Lysosomal abnormalities in degenerating neurons link neuronal compromise to senile plaque development in Alzheimer disease

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https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Lysosomal hydrolases of different classes are abnormally distributed in brains of patients with Alzheimer disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Re-expression of the mannose 6-phosphate receptors in receptor-deficient fibroblasts. Complementary function of the two mannose 6-phosphate receptors in lysosomal enzyme targeting

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

The Two Mannose 6-Phosphate Receptors Transport Distinct Complements of Lysosomal Proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

The pathway and targeting signal for delivery of the integral membrane glycoprotein LEP100 to lysosomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Differences in the endosomal distributions of the two mannose 6-phosphate receptors

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https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

A determinant in the cytoplasmic tail of the cation-dependent mannose 6-phosphate receptor prevents trafficking to lysosomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Proper sorting of the cation-dependent mannose 6-phosphate receptor in endosomes depends on a pair of aromatic amino acids in its cytoplasmic tail

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

The FYVE domain of early endosome antigen 1 is required for both phosphatidylinositol 3-phosphate and Rab5 binding. Critical role of this dual interaction for endosomal localization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Protease nexin-II, a potent antichymotrypsin, shows identity to amyloid beta-protein precursor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Neuropathological stageing of Alzheimer-related changes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Mutant presenilin 1 increases the levels of Alzheimer amyloid beta-peptide Abeta42 in late compartments of the constitutive secretory pathway.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Degradation and endoplasmic reticulum retention of unassembled alpha- and beta-subunits of Na,K-ATPase correlate with interaction of BiP.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Quantification of sub-femtomole amounts of Alzheimer amyloid beta peptides.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Plasma and cerebrospinal fluid levels of amyloid beta proteins 1-40 and 1-42 in Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Intracellular movement of two mannose 6-phosphate receptors: return to the Golgi apparatus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

A single amino acid change in the cytoplasmic domain allows the influenza virus hemagglutinin to be endocytosed through coated pits

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Characteristics of the tyrosine recognition signal for internalization of transmembrane surface glycoproteins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Heterologous transmembrane and cytoplasmic domains direct functional chimeric influenza virus hemagglutinins into the endocytic pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Identification, sequencing and expression of an integral membrane protein of the trans-Golgi network (TGN38)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Probing the cathepsin D using a BODIPY FL-pepstatin A: applications in fluorescence polarization and microscopy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Metabolism of the "Swedish" amyloid precursor protein variant in neuro2a (N2a) cells. Evidence that cleavage at the "beta-secretase" site occurs in the golgi apparatus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

The phosphatidylinositol 3-kinase inhibitor wortmannin alters the metabolism of the Alzheimer's amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Expression of beta-amyloid precursor protein-CD3gamma chimeras to demonstrate the selective generation of amyloid beta(1-40) and amyloid beta(1-42) peptides within secretory and endocytic compartments

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Cathepsin D displays in vitro beta-secretase-like specificity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Processing of the Pre‐β‐amyloid Protein by Cathepsin d is Enhanced by a Familial Alzheimer's Disease Mutation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

A possible role for cathepsins D, E, and B in the processing of beta-amyloid precursor protein in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Genetic polymorphism of cathepsin D is strongly associated with the risk for developing sporadic Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Non-replication of association between cathepsin D genotype and late onset Alzheimer disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

No evidence for genetic association or linkage of the cathepsin D (CTSD) exon 2 polymorphism and Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Candidate genes showing no evidence for association or linkage with Alzheimer's disease using family-based methodologies.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Amyloidogenic processing of human amyloid precursor protein in hippocampal neurons devoid of cathepsin D.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Consensus Report of the Working Group on: “Molecular and Biochemical Markers of Alzheimer’s Disease” 11The names of the Working Group Members and the names of the Working Group Advisory Committee Members are listed in the Appendix A(section VI)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

The mannose 6-phosphate receptor and the biogenesis of lysosomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108161200

21 January 2018

Identifiers

10.1074/JBC.M108161200

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

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