The structural repertoire of the human V kappa domain (Q40789466)

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20 October 2019

title

The structural repertoire of the human V kappa domain (English)

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20 October 2019

5

Chothia C

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20 October 2019

4

Lesk AM

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20 October 2019

Tomlinson IM

1

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20 October 2019

Cox JP

series ordinal

2

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20 October 2019

Gherardi E

series ordinal

3

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20 October 2019

language of work or name

English

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publication date

1 September 1995

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20 October 2019

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20 October 2019

volume

14

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issue

18

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20 October 2019

page(s)

4628-4638

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Modulation of antibody affinity by a non-contact residue

20 October 2019

cites work

1 reference

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Routes to catalysis: structure of a catalytic antibody and comparison with its natural counterpart

24 September 2017

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The variable genes of the human immunoglobulin kappa locus

24 September 2017

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The immunoglobulin kappa locus-or-what has been learned from looking closely at one-tenth of a percent of the human genome

24 September 2017

1 reference

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The contribution of contact and non-contact residues of antibody in the affinity of binding to antigen. The interaction of mutant D1.3 antibodies with lysozyme

24 September 2017

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Expressed human immunoglobulin kappa genes and their hypermutation

24 September 2017

1 reference

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The V kappa genes of the L regions and the repertoire of V kappa gene sequences in the human germ line

24 September 2017

1 reference

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Structural mechanisms for domain movements in proteins

24 September 2017

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Major antigen-induced domain rearrangements in an antibody

24 September 2017

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X-ray structures of fragments from binding and nonbinding versions of a humanized anti-CD18 antibody: structural indications of the key role of VH residues 59 to 65

24 September 2017

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Enhancement and destruction of antibody function by somatic mutation: unequal occurrence is controlled by V gene combinatorial associations.

24 September 2017

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Antibody-antigen interactions: new structures and new conformational changes

24 September 2017

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Structure of an antibody-lysozyme complex unexpected effect of conservative mutation

24 September 2017

1 reference

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Human immunoglobulin variable region genes--DNA sequences of two V kappa genes and a pseudogene

24 September 2017

1 reference

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Immunoglobulin genes of different subgroups are interdigitated within the VK locus

24 September 2017

1 reference

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Evolution of immunoglobulin V genes: evidence indicating that recently duplicated human V kappa sequences have diverged by gene conversion

24 September 2017

1 reference

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Somatic generation of antibody diversity

24 September 2017

1 reference

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Evolution of human immunoglobulin kappa J region genes

24 September 2017

1 reference

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Composite human VKgenes and a model of their evolution

24 September 2017

1 reference

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The Three-Dimensional Structure of a Phosphorylcholine-Binding Mouse Immunoglobulin Fab and the Nature of the Antigen Binding Site

24 September 2017

1 reference

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Aberrant recombination events in B cell lines derived from a kappa-deficient human

24 September 2017

1 reference

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Mutation drift and repertoire shift in the maturation of the immune response

24 September 2017

1 reference

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Isolation and characterization of a light chain variable region gene for human rheumatoid factors

24 September 2017

1 reference

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Genetic basis for the cross-reactive idiotypes on the light chains of human IgM anti-IgG autoantibodies

24 September 2017

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A conserved human germline V kappa gene directly encodes rheumatoid factor light chains

24 September 2017

1 reference

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Subgroup IV of human immunoglobulin K light chains is encoded by a single germline gene

24 September 2017

1 reference

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Three-dimensional structure of Fab R19.9, a monoclonal murine antibody specific for the p-azobenzenearsonate group

24 September 2017

1 reference

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Conformations of immunoglobulin hypervariable regions

24 September 2017

1 reference

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Characterization of four homologous L chain variable region genes that are related to 6B6.6 idiotype positive human rheumatoid factor L chains

24 September 2017

1 reference

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Three-dimensional structure of an antibody-antigen complex

24 September 2017

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Three-dimensional structure of a complex of antibody with influenza virus neuraminidase

24 September 2017

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Structural correlates of high antibody affinity: three engineered amino acid substitutions can increase the affinity of an anti-p-azophenylarsonate antibody 200-fold

24 September 2017

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The structure of protein-protein recognition sites

24 September 2017

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Antibody-antigen complexes

24 September 2017

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2.9 A resolution structure of an anti-dinitrophenyl-spin-label monoclonal antibody Fab fragment with bound hapten

24 September 2017

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Selection of phage antibodies by binding affinity. Mimicking affinity maturation

24 September 2017

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Structure of a human monoclonal antibody Fab fragment against gp41 of human immunodeficiency virus type 1

24 September 2017

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Refined crystal structure of a recombinant immunoglobulin domain and a complementarity-determining region 1-grafted mutant

24 September 2017

1 reference

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Three-dimensional structure determination of an anti-2-phenyloxazolone antibody: the role of somatic mutation and heavy/light chain pairing in the maturation of an immune response

25 September 2017

1 reference

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Essential residues in V(D)J recombination signals

25 September 2017

1 reference

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A directory of human germ-line V kappa segments reveals a strong bias in their usage

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394555

The human immunoglobulin kappa locus: pseudogenes, unique and repetitive sequences.

15 June 2018

1 reference

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Organization and evolution of a gene cluster for human immunoglobulin variable regions of the kappa type

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394555

Crystal and molecular structure of a dimer composed of the variable portions of the Bence-Jones protein REI.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394555

Two unusual human immunoglobulin V kappa genes

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394555

Clonal characterization of the human IgG antibody repertoire to Haemophilus influenzae type b polysaccharide. IV. The less frequently expressed VL are heterogeneous.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394555

The human immunoglobulin kappa locus. Characterization of the duplicated O regions.

15 June 2018

1 reference

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Non-random features of the repertoire expressed by the members of one V kappa gene family and of the V-J recombination.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394555

The human immunoglobulin kappa locus. Characterization of the duplicated A regions

15 June 2018

1 reference

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Structural evidence for induced fit as a mechanism for antibody-antigen recognition

15 June 2018

1 reference

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Structural repertoire of the human VH segments

15 June 2018

1 reference

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A large section of the gene locus encoding human immunoglobulin variable regions of the kappa type is duplicated

15 June 2018

1 reference

12 December 2020

Three-dimensional structure of an antigen-antibody complex at 2.8 A resolution

1 reference

12 December 2020

Canonical structures for the hypervariable regions of immunoglobulins

1 reference

12 December 2020

The human VK locus. Characterization of a duplicated region encoding 28 different immunoglobulin genes

1 reference

12 December 2020

The galactan-binding immunoglobulin Fab J539: an X-ray diffraction study at 2.6-A resolution

1 reference

12 December 2020

The J kappa proximal region of the human K locus contains three uncommon V kappa genes which are arranged in opposite transcriptional polarities

1 reference

12 December 2020

Clonal characterization of the human IgG antibody repertoire to Haemophilus influenzae type b polysaccharide. III. A single VKII gene and one of several JK genes are joined by an invariant arginine to form the most common L chain V region

1 reference

12 December 2020

Small rearrangements in structures of Fv and Fab fragments of antibody D1.3 on antigen binding

1 reference

12 December 2020

Single-chain site-specific mutations of fluorescein-amino acid contact residues in high affinity monoclonal antibody 4-4-20

1 reference

12 December 2020

Antibody framework residues affecting the conformation of the hypervariable loops

1 reference

12 December 2020

A mutated promoter of a human Ig V lambda gene segment is associated with reduced germ-line transcription and a low frequency of rearrangement

1 reference

12 December 2020

Attempts to locate complementarity-determining residues in the variable positions of light and heavy chains

1 reference

12 December 2020

Crystallographic refinement and atomic models of the intact immunoglobulin molecule Kol and its antigen-binding fragment at 3.0 A and 1.0 A resolution

1 reference

12 December 2020

10.1002/J.1460-2075.1995.TB00142.X

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7556106%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7556106%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

1 reference