P21(Cip1) induced by Raf is associated with increased Cdk4 activity in hematopoietic cells. (Q40790669)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11466616%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

P21(Cip1) induced by Raf is associated with increased Cdk4 activity in hematopoietic cells (English)

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9 November 2019

2

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9 November 2019

author name string

F Chang

series ordinal

1

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9 November 2019

language of work or name

English

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publication date

1 July 2001

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9 November 2019

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9 November 2019

volume

20

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9 November 2019

issue

32

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9 November 2019

page(s)

4354-4364

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c-Raf kinase binds to N-terminal domain of c-Myc

9 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Key role of the cyclin-dependent kinase inhibitor p27kip1 for embryonal carcinoma cell survival and differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

The Raf-1/MEK/ERK pathway regulates the expression of the p21(Cip1/Waf1) gene in chondrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Cell death beyond apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Signal transduction, cell cycle regulatory, and anti-apoptotic pathways regulated by IL-3 in hematopoietic cells: possible sites for intervention with anti-neoplastic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Mutations of critical amino acids affect the biological and biochemical properties of oncogenic A-Raf and Raf-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Two distinct Raf domains mediate interaction with Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Activity and nature of p21(WAF1) complexes during the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Functional divergence of the MAP kinase pathway. ERK1 and ERK2 activate specific transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Cyclin-binding motifs are essential for the function of p21CIP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

The ins and outs of Raf kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

The roles of signaling by the p42/p44 mitogen-activated protein (MAP) kinase pathway; a potential route to radio- and chemo-sensitization of tumor cells resulting in the induction of apoptosis and loss of clonogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Ras interaction with two distinct binding domains in Raf-1 may be required for Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Critical Tyrosine Residues Regulate the Enzymatic and Biological Activity of Raf-1 Kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Activation of Raf-1 by 14-3-3 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Binding of 14-3-3 proteins to the protein kinase Raf and effects on its activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Molecular cloning and characterization of an activated human c-raf-1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

MAP kinase binds to the NH2-terminal activation domain of c-Myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Isotype-specific functions of Raf kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Inhibition of cyclin-dependent kinases by p21

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Mutational activation of c-raf-1 and definition of the minimal transforming sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Identification of CDK4 as a target of c-MYC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by a MEK1-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Ras-induced activation of Raf-1 is dependent on tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Regulation of survival pathways by IL-3 and induction of apoptosis following IL-3 withdrawal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Regulation of c-myc expression by Ras/Raf signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Cell cycle targets of Ras/Raf signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

New functional activities for the p21 family of CDK inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

The complete sequence and promoter activity of the human A-raf-1 gene (ARAF1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Analysis of wild-type and mutant p21WAF-1 gene activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Differential regulation of Raf-1, A-Raf, and B-Raf by oncogenic ras and tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Interactions between Ras and Raf: key regulatory proteins in cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

c-Myc regulates cyclin D-Cdk4 and -Cdk6 activity but affects cell cycle progression at multiple independent points

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

D-type cyclin-dependent kinase activity in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Serine/threonine phosphorylation in cytokine signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Synergy between Raf and BCL2 in abrogating the cytokine dependency of hematopoietic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Raf-1 protein is required for growth factor-induced proliferation of hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Direct interaction of p21 cyclin-dependent kinase inhibitor with the retinoblastoma tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Humoral regulation of hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Cell cycle activation by c-myc in a burkitt lymphoma model cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Cyclin-dependent kinases are inactivated by a combination of p21 and Thr-14/Tyr-15 phosphorylation after UV-induced DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Conditionally oncogenic forms of the A-Raf and B-Raf protein kinases display different biological and biochemical properties in NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Post-natal lethality and neurological and gastrointestinal defects in mice with targeted disruption of the A-Raf protein kinase gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Identification of a novel class of genomic DNA-binding sites suggests a mechanism for selectivity in target gene activation by the tumor suppressor protein p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Biochemical Analysis of MEK Activation in NIH3T3 Fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Activation of the Raf/MAP kinase cascade by the Ras-related protein TC21 is required for the TC21-mediated transformation of NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Cyclin E-CDK2 is a regulator of p27Kip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Understanding Ras: 'it ain't over 'til it's over'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Definition of the human raf amino-terminal regulatory region by deletion mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

A phosphatidylinositol 3-kinase-dependent pathway that differentially regulates c-Raf and A-Raf

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

A dimeric 14-3-3 protein is an essential cofactor for Raf kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Four human ras homologs differ in their abilities to activate Raf-1, induce transformation, and stimulate cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Mammalian Ras interacts directly with the serine/threonine kinase Raf

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Mitogenic signaling of Ras is regulated by differential interaction with Raf isozymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Endothelial apoptosis in Braf-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Craf-1 protein kinase is essential for mouse development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Sodium butyrate induces NIH3T3 cells to senescence-like state and enhances promoter activity of p21WAF/CIP1 in p53-independent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

p21 is a universal inhibitor of cyclin kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Ras-induced transformation and signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

p21-containing cyclin kinases exist in both active and inactive states

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Signal TransductionThrough Cytokine Receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

The Protein SET Regulates the Inhibitory Effect of p21Cip1on Cyclin E-Cyclin-dependent Kinase 2 Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

Stimulatory effects of yeast and mammalian 14-3-3 proteins on the Raf protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

7 January 2021

In vitro transcriptional activation of p21 promoter by p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

7 January 2021

Different effects of various phospholipids on Ki-Ras-, Ha-Ras-, and Rap1B-induced B-Raf activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

7 January 2021

Inhibition of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase pathway induces p53-independent transcriptional regulation of p21(WAF1/CIP1) in human prostate carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

7 January 2021

p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

7 January 2021

Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

7 January 2021

Expression and modulation of p42/p44 MAPKs and cell cycle regulatory proteins in rat pancreas regeneration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

7 January 2021

Cdk2-dependent phosphorylation of p27 facilitates its Myc-induced release from cyclin E/cdk2 complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

7 January 2021

Raf revealed in life-or-death decisions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

7 January 2021

Positive and negative regulation of c-Myc transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204564

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204564

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11466616%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 November 2019

1021910338

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Fatcat ID

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Fatcat

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24 November 2022

mapped directly with Wikidata item

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