Constitutively active STAT5 variants induce growth and survival of hematopoietic cells through a PI 3-kinase/Akt dependent pathway. (Q40804665)

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7 November 2019

title

Constitutively active STAT5 variants induce growth and survival of hematopoietic cells through a PI 3-kinase/Akt dependent pathway (English)

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7 November 2019

5

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author name string

Santos SC

1

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7 November 2019

Lacronique V

2

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Bouchaert I

3

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Monni R

4

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7 November 2019

Gisselbrecht S

6

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Gouilleux F

7

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language of work or name

English

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publication date

1 April 2001

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7 November 2019

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volume

20

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7 November 2019

page(s)

2080-2090

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issue

17

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1204308

7 November 2019

exact match

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cites work

Evidence for a role of NF-kappaB in the survival of hematopoietic cells mediated by interleukin 3 and the oncogenic TEL/platelet-derived growth factor receptor beta fusion protein

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Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl

21 January 2018

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AH/PH domain-mediated interaction between Akt molecules and its potential role in Akt regulation

21 January 2018

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Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

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IL-3 dependent regulation of Bcl-xL gene expression by STAT5 in a bone marrow derived cell line

21 January 2018

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The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

21 January 2018

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Multiple ras effector pathways contribute to G(1) cell cycle progression

21 January 2018

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Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation

21 January 2018

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Phosphatidylinositol 3-kinase

21 January 2018

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Two distinct interleukin-3-mediated signal pathways, Ras-NFIL3 (E4BP4) and Bcl-xL, regulate the survival of murine pro-B lymphocytes

21 January 2018

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A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia

21 January 2018

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In bone marrow derived Baf-3 cells, inhibition of apoptosis by IL-3 is mediated by two independent pathways.

21 January 2018

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Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells

21 January 2018

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Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells

21 January 2018

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The survival function of the Bcr-Abl oncogene is mediated by Bad-dependent and -independent pathways: roles for phosphatidylinositol 3-kinase and Raf.

21 January 2018

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Identification and characterization of a constitutively active STAT5 mutant that promotes cell proliferation

21 January 2018

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STAT3 as an adapter to couple phosphatidylinositol 3-kinase to the IFNAR1 chain of the type I interferon receptor

21 January 2018

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Cooperation between STAT5 and phosphatidylinositol 3-kinase in the IL-3-dependent survival of a bone marrow derived cell line

21 January 2018

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Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway.

21 January 2018

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Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction

21 January 2018

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Erythropoietin induces the tyrosine phosphorylation of insulin receptor substrate-2. An alternate pathway for erythropoietin-induced phosphatidylinositol 3-kinase activation

21 January 2018

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The leukaemic oncoproteins Bcr-Abl and Tel-Abl (ETV6/Abl) have altered substrate preferences and activate similar intracellular signalling pathways.

21 January 2018

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Growth hormone and prolactin stimulate tyrosine phosphorylation of insulin receptor substrate-1, -2, and -3, their association with p85 phosphatidylinositol 3-kinase (PI3-kinase), and concomitantly PI3-kinase activation via JAK2 kinase

21 January 2018

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Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

21 January 2018

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Cyclin D Expression Is Controlled Post-transcriptionally via a Phosphatidylinositol 3-Kinase/Akt-dependent Pathway

21 January 2018

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Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F

21 January 2018

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7 January 2021

Dissociation of apoptosis from proliferation, protein kinase B activation, and BAD phosphorylation in interleukin-3-mediated phosphoinositide 3-kinase signaling

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7 January 2021

Interleukin-3 induces association of the protein-tyrosine phosphatase SHP2 and phosphatidylinositol 3-kinase with a 100-kDa tyrosine-phosphorylated protein in hemopoietic cells

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7 January 2021

Identification of tyrosine residues within the intracellular domain of the erythropoietin receptor crucial for STAT5 activation

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7 January 2021

Signaling by the cytokine receptor superfamily

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204308

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11360192%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

7 November 2019

0 references

1 reference