The p38 mitogen-activated protein kinase cascade modulates T helper type 17 differentiation and functionality in multiple sclerosis (Q40815617)

24 September 2017

The p38 mitogen-activated protein kinase cascade modulates T helper type 17 differentiation and functionality in multiple sclerosis (English)

1 reference

24 September 2017

0 references

1

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13 June 2020

Manolo Sambucci

2

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13 June 2020

Marco De Bardi

4

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13 June 2020

Claudio Gasperini

7

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13 June 2020

Diego Centonze

8

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13 June 2020

Claudio Sette

9

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13 June 2020

Arne N Akbar

10

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13 June 2020

Giovanna Borsellino

11

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13 June 2020

author name string

Maria Loiarro

3

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13 June 2020

Elisabetta Volpe

5

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13 June 2020

Maria Teresa Cencioni

6

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13 June 2020

Luca Battistini

12

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13 June 2020

publication date

12 June 2015

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24 September 2017

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13 June 2020

volume

146

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13 June 2020

issue

2

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13 June 2020

page(s)

251-263

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Cellular signaling in the aging immune system

13 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4582966

Functional roles of p38 mitogen-activated protein kinase in macrophage-mediated inflammatory responses

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4582966

High glucose driven expression of pro-inflammatory cytokine and chemokine genes in lymphocytes: molecular mechanisms of IL-17 family gene expression

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4582966

Mechanism for p38α-mediated experimental autoimmune encephalomyelitis

29 August 2018

1 reference

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Signaling via the kinase p38α programs dendritic cells to drive TH17 differentiation and autoimmune inflammation

29 August 2018

1 reference

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Selective involvement of ERK and JNK mitogen-activated protein kinases in early rheumatoid arthritis (1987 ACR criteria compared to 2010 ACR/EULAR criteria): a prospective study aimed at identification of diagnostic and prognostic biomarkers as well

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4582966

Mouse T helper 17 phenotype: not so different than in man after all.

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4582966

Activation of p38 MAPK in CD4 T cells controls IL-17 production and autoimmune encephalomyelitis

29 August 2018

1 reference

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Reversible senescence in human CD4+CD45RA+CD27- memory T cells.

29 August 2018

1 reference

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Lack of the T cell-specific alternative p38 activation pathway reduces autoimmunity and inflammation

29 August 2018

1 reference

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New drugs beyond biologics in rheumatoid arthritis: the kinase inhibitors

29 August 2018

1 reference

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IL-17 receptor signaling and T helper 17-mediated autoimmune demyelinating disease

29 August 2018

1 reference

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Activation of p38 mitogen-activated protein kinase is critical step for acquisition of effector function in cytokine-activated T cells, but acts as a negative regulator in T cells activated through the T-cell receptor.

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4582966

Role of SMAD and non-SMAD signals in the development of Th17 and regulatory T cells

29 August 2018

1 reference

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Kinase inhibitors: a new approach to rheumatoid arthritis treatment

29 August 2018

1 reference

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"Go upstream, young man": lessons learned from the p38 saga

29 August 2018

1 reference

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Selective p38alpha inhibitors clinically evaluated for the treatment of chronic inflammatory disorders

29 August 2018

1 reference

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T-helper 17 cells expand in multiple sclerosis and are inhibited by interferon-beta.

29 August 2018

1 reference

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Plasticity of CD4+ T cell lineage differentiation.

29 August 2018

1 reference

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29 August 2018

1 reference

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P38 MAP kinase signaling is required for the conversion of CD4+CD25- T cells into iTreg

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4582966

The biological functions of T helper 17 cell effector cytokines in inflammation

29 August 2018

1 reference

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MAPKs and their relevance to arthritis and inflammation

29 August 2018

1 reference

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Th17 cells: a new fate for differentiating helper T cells

29 August 2018

1 reference

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Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis

29 August 2018

1 reference

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The role of the p38 pathway in adaptive immunity.

29 August 2018

1 reference

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IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells

29 August 2018

1 reference

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A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

29 August 2018

1 reference

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Potential adverse effects associated with inhibition of p38alpha/beta MAP kinases

29 August 2018

1 reference

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Premature immunosenescence in rheumatoid arthritis and multiple sclerosis patients

29 August 2018

1 reference

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Alternative p38 activation pathway mediated by T cell receptor-proximal tyrosine kinases

29 August 2018

1 reference

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IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

29 August 2018

1 reference

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p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases

29 August 2018

1 reference

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Activation of mitogen-activated protein kinases in experimental autoimmune encephalomyelitis.

29 August 2018

1 reference

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JNK and p38 MAP kinases in CD4+ and CD8+ T cells

29 August 2018

1 reference

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Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4582966

29 August 2018

1 reference

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Activation of the p38 mitogen-activated protein kinase pathway arrests cell cycle progression and differentiation of immature thymocytes in vivo

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4582966

Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4582966

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4582966

Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity

29 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4582966

Tyr³²³-dependent p38 activation is associated with rheumatoid arthritis and correlates with disease activity

29 August 2018

1 reference

12 December 2020

Cerebrospinal fluid and serum protein levels of tumour necrosis factor-alpha (TNF-alpha) interleukin-6 (IL-6) and soluble interleukin-6 receptor (sIL-6R gp80) in multiple sclerosis patients

1 reference

12 December 2020

Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function

1 reference

12 December 2020

Variations of IL2, IL6, TNF alpha plasmatic levels in relapsing remitting multiple sclerosis

1 reference

12 December 2020

IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis

1 reference

12 December 2020

The Mnks are novel components in the control of TNF alpha biosynthesis and phosphorylate and regulate hnRNP A1

1 reference

12 December 2020

IL-21 Counteracts the Regulatory T Cell-Mediated Suppression of Human CD4+ T Lymphocytes

1 reference

12 December 2020

A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses

1 reference

12 December 2020

p38{alpha} MAP kinase controls IL-17 synthesis in vogt-koyanagi-harada syndrome and experimental autoimmune uveitis

1 reference

12 December 2020

Identifiers

DOI

10.1111/IMM.12497

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26095162%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26095162%20AND%20SRC:MED&resulttype=core&format=json