Bcr-Abl protein tyrosine kinase activity induces a loss of p53 protein that mediates a delay in myeloid differentiation (Q40837798)

24 September 2017

title

Bcr-Abl protein tyrosine kinase activity induces a loss of p53 protein that mediates a delay in myeloid differentiation (English)

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24 September 2017

1

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24 September 2017

2

Spooncer E

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24 September 2017

Wooley S

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24 September 2017

Dive C

4

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24 September 2017

Francis JM

5

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24 September 2017

Miyan J

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24 September 2017

Owen-Lynch PJ

7

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24 September 2017

Dexter TM

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24 September 2017

Whetton AD

9

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24 September 2017

language of work or name

English

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publication date

1 November 2000

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24 September 2017

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24 September 2017

volume

19

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24 September 2017

issue

48

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24 September 2017

page(s)

5487-5497

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1203940

24 September 2017

exact match

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cites work

Alterations in the p53 gene and the clonal evolution of the blast crisis of chronic myelocytic leukemia

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The spectrum of molecular alterations in the evolution of chronic myelocytic leukemia

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A functional analysis of p53 during early development of Xenopus laevis.

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Oncogenic Abl and Src tyrosine kinases elicit the ubiquitin-dependent degradation of target proteins through a Ras-independent pathway

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Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein

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Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome

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JNK targets p53 ubiquitination and degradation in nonstressed cells

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MEKK1/JNK signaling stabilizes and activates p53.

21 January 2018

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Acute leukaemia in bcr/abl transgenic mice

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Autocrine production and action of IL-3 and granulocyte colony-stimulating factor in chronic myeloid leukemia.

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Expression of the GM-CSF gene after retroviral transfer in hematopoietic stem cell lines induces synchronous granulocyte-macrophage differentiation

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Induction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and BCR/ABL.

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An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity.

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Markers of mouse macrophage development detected by monoclonal antibodies

21 January 2018

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p53, the cellular gatekeeper for growth and division

21 January 2018

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Tyrosine kinase activity and transformation potency of bcr-abl oncogene products.

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BCR-ABL accelerates C2-ceramide-induced apoptosis

21 January 2018

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Inactivation of p53 results in high rates of homologous recombination

21 January 2018

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Chromosome 17 abnormalities and inactivation of the p53 gene in chronic myeloid leukemia and their prognostic significance

21 January 2018

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Functional and biochemical phenotype in relation to cellular age of differentiated neutrophils in chronic myeloid leukaemia

21 January 2018

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p210 Bcr-Abl expression in a primitive multipotent haematopoietic cell line models the development of chronic myeloid leukaemia.

21 January 2018

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The Bcr-Abl leukemia oncogene activates Jun kinase and requires Jun for transformation

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Regulation of ES cell differentiation by functional and conformational modulation of p53.

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Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding

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Blastic transformation of p53-deficient bone marrow cells by p210bcr/abl tyrosine kinase.

21 January 2018

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Interference with p53 protein inhibits hematopoietic and muscle differentiation

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Self-renewal and differentiation of interleukin-3-dependent multipotent stem cells are modulated by stromal cells and serum factors

21 January 2018

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Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation

21 January 2018

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Biology of chronic myelogenous leukemia

21 January 2018

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Initiation of deregulated growth of multipotent progenitor cells by bcr-abl in vitro

21 January 2018

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7 January 2021

A temperature sensitive p210 BCR-ABL mutant defines the primary consequences of BCR-ABL tyrosine kinase expression in growth factor dependent cells.

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7 January 2021

Hemizygous expression of the wild-type p53 allele may confer a selective growth advantage before complete inactivation of the p53 gene in the progression of chronic myelogenous leukaemia

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203940

7 January 2021

P53 tumor suppressor gene in chronic myelogenous leukemia: a sequential study

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7 January 2021

Analysis of the p53 and MDM-2 gene in acute myeloid leukemia

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203940

7 January 2021

p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203940

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203940

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Dimensions Publication ID

24 September 2017

1010634852

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1 reference