Factor VIIa/tissue factor-induced signaling via activation of Src-like kinases, phosphatidylinositol 3-kinase, and Rac. (Q40874501)

24 September 2017

title

Factor VIIa/tissue factor-induced signaling via activation of Src-like kinases, phosphatidylinositol 3-kinase, and Rac. (English)

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24 September 2017

5

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24 September 2017

Versteeg HH

1

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24 September 2017

Hoedemaeker I

2

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24 September 2017

Diks SH

3

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24 September 2017

Stam JC

4

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24 September 2017

van Bergen En Henegouwen PM

6

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24 September 2017

van Deventer SJ

7

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24 September 2017

Peppelenbosch MP

8

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24 September 2017

language of work or name

English

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publication date

1 September 2000

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Journal of Biological Chemistry

24 September 2017

number of pages

7

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based on heuristic

inferred from page(s)

published in

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24 September 2017

volume

275

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24 September 2017

issue

37

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24 September 2017

page(s)

28750-28756

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Fatal embryonic bleeding events in mice lacking tissue factor, the cell-associated initiator of blood coagulation

24 September 2017

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Effect of tissue factor deficiency on mouse and tumor development

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Tissue factor pathway inhibitor reduces mortality from Escherichia coli septic shock

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Tissue factor controls the balance of angiogenic and antiangiogenic properties of tumor cells in mice

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Crystal structure of the extracellular region of human tissue factor

21 January 2018

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Binding of human factor VIIa to tissue factor induces cytosolic Ca2+ signals in J82 cells, transfected COS-1 cells, Madin-Darby canine kidney cells and in human endothelial cells induced to synthesize tissue factor

21 January 2018

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Coagulation factors VII and X induce Ca2+ oscillations in Madin-Darby canine kidney cells only when proteolytically active

21 January 2018

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Binding of factor VIIa to tissue factor induces alterations in gene expression in human fibroblast cells: up-regulation of poly(A) polymerase

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RhoE regulates actin cytoskeleton organization and cell migration.

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Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation

21 January 2018

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Rac mediates growth factor-induced arachidonic acid release.

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An essential role for Rac in Ras transformation

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Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

21 January 2018

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PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

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Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase

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A role for tissue factor in cell adhesion and migration mediated by interaction with actin-binding protein 280.

21 January 2018

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Localization of human tissue factor antigen by immunostaining with monospecific, polyclonal anti-human tissue factor antibody

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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

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A brain serine/threonine protein kinase activated by Cdc42 and Rac1

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Regulation of TNF-alpha-induced reorganization of the actin cytoskeleton and cell-cell junctions by Rho, Rac, and Cdc42 in human endothelial cells

21 January 2018

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Insulin signal transduction through protein kinase cascades

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Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

21 January 2018

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A target for Src in mitosis.

21 January 2018

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An RNA-binding protein associated with Src through its SH2 and SH3 domains in mitosis

21 January 2018

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The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

21 January 2018

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Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

21 January 2018

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An inhibitor of p38 mitogen-activated protein kinase prevents insulin-stimulated glucose transport but not glucose transporter translocation in 3T3-L1 adipocytes and L6 myotubes

21 January 2018

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Different protein tyrosine kinases are required for B cell antigen receptor-mediated activation of extracellular signal-regulated kinase, c-Jun NH2-terminal kinase 1, and p38 mitogen-activated protein kinase.

21 January 2018

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Distinct roles for the p110alpha and hVPS34 phosphatidylinositol 3'-kinases in vesicular trafficking, regulation of the actin cytoskeleton, and mitogenesis

21 January 2018

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A heterotrimeric GTPase-regulated isoform of PI3K and the regulation of its potential effectors

21 January 2018

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A role for Rac in Tiam1-induced membrane ruffling and invasion

21 January 2018

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Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation

21 January 2018

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The Rac and Rho pathways as a source of drug targets for Ras-mediated malignancies

21 January 2018

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Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

21 January 2018

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Identification of a new adapter protein that may link the common beta subunit of the receptor for granulocyte/macrophage colony-stimulating factor, interleukin (IL)-3, and IL-5 to phosphatidylinositol 3-kinase.

21 January 2018

1 reference

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Factor VIIa-induced p44/42 mitogen-activated protein kinase activation requires the proteolytic activity of factor VIIa and is independent of the tissue factor cytoplasmic domain

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M907635199

1 reference

24 September 2017

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