Different functions are required for initiation and maintenance of immortalization of rat embryo fibroblasts by SV40 large T antigen. (Q40911268)

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2 November 2019

title

Different functions are required for initiation and maintenance of immortalization of rat embryo fibroblasts by SV40 large T antigen (English)

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2 November 2019

4

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2 November 2019

author name string

Powell AJ

1

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2 November 2019

Darmon AJ

2

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2 November 2019

Gonos ES

3

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2 November 2019

Peden KW

5

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2 November 2019

Jat PS

6

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2 November 2019

language of work or name

English

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publication date

1 December 1999

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2 November 2019

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2 November 2019

volume

18

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2 November 2019

issue

51

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2 November 2019

page(s)

7343-7350

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1203154

2 November 2019

exact match

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cites work

Biochemical Activities of T-Antigen Proteins Encoded by Simian Virus 40 A Gene Deletion Mutants

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SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

21 January 2018

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The cellular 107K protein that binds to adenovirus E1A also associates with the large T antigens of SV40 and JC virus

21 January 2018

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An N-terminal transformation-governing sequence of SV40 large T antigen contributes to the binding of both p110Rb and a second cellular protein, p120.

21 January 2018

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Rat embryo fibroblasts immortalized with simian virus 40 large T antigen undergo senescence upon its inactivation

21 January 2018

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Transcriptional activation by simian virus 40 large T antigen: interactions with multiple components of the transcription complex

21 January 2018

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The serial cultivation of human diploid cell strains

21 January 2018

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The biological clock that measures the mitotic life-span of mouse embryo fibroblasts continues to function in the presence of simian virus 40 large tumor antigen

21 January 2018

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Cell lines established by a temperature-sensitive simian virus 40 large-T-antigen gene are growth restricted at the nonpermissive temperature

21 January 2018

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The J-domain family and the recruitment of chaperone power

21 January 2018

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Simian virus 40 small tumor antigen and an amino-terminal domain of large tumor antigen share a common transforming function

21 January 2018

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Mutants with changes within or near a hydrophobic region of simian virus 40 large tumor antigen are defective for binding cellular protein p53.

21 January 2018

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Effects of mutations within the SV40 large T antigen ATPase/p53 binding domain on viral replication and transformation

21 January 2018

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Mutational Analysis of Simian Virus 40 T Antigen: Isolation and Characterization of Mutants with Deletions in the T-Antigen Gene

21 January 2018

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Immortalization of rat embryo fibroblasts by a 3'-untranslated region

21 January 2018

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Maintenance of cellular proliferation by adenovirus early region 1A in fibroblasts conditionally immortalized by using simian virus 40 large T antigen requires conserved region 1.

21 January 2018

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Down-regulation of Ku autoantigen, DNA-dependent protein kinase, and poly(ADP-ribose) polymerase during cellular senescence

21 January 2018

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The amino-terminal 147 amino acids of SV40 large T antigen transform secondary rat embryo fibroblasts

21 January 2018

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The amino-terminal transforming region of simian virus 40 large T and small t antigens functions as a J domain.

21 January 2018

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Inactivation of pRB-related proteins p130 and p107 mediated by the J domain of simian virus 40 large T antigen.

21 January 2018

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Use of transgenic mice reveals cell-specific transformation by a simian virus 40 T-antigen amino-terminal mutant

21 January 2018

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Two regions of simian virus 40 large T-antigen independently extend the life span of primary C57BL/6 mouse embryo fibroblasts and cooperate in immortalization

21 January 2018

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Dissociation of Rb-binding and anchorage-independent growth from immortalization and tumorigenicity using SV40 mutants producing N-terminally truncated large T antigens

21 January 2018

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Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines

21 January 2018

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Simian virus 40 large-T antigen expresses a biological activity complementary to the p300-associated transforming function of the adenovirus E1A gene products

21 January 2018

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The J domain of simian virus 40 large T antigen is required to functionally inactivate RB family proteins.

21 January 2018

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Cell cycle regulation of E2F site occupation in vivo.

21 January 2018

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A region of SV40 large T antigen can substitute for a transforming domain of the adenovirus E1A products

21 January 2018

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Inactivation of the retinoblastoma susceptibility protein is not sufficient for the transforming function of the conserved region 2-like domain of simian virus 40 large T antigen.

21 January 2018

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7 January 2021

Monoclonal antibodies specific for simian virus 40 tumor antigens

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7 January 2021

Activated Ha-ras can cooperate with defective simian virus 40 in the transformation of nonestablished rat embryo fibroblasts

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7 January 2021

A DNA replication-positive mutant of simian virus 40 that is defective for transformation and the production of infectious virions

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7 January 2021

Immortalization of rodent embryo fibroblasts by SV40 Is maintained by the Å gene

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7 January 2021

A novel simian virus 40 early-region domain mediates transactivation of the cyclin A promoter by small-t antigen and is required for transformation in small-t antigen-dependent assays.

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7 January 2021

The DnaJ domain of polyomavirus large T antigen is required to regulate Rb family tumor suppressor function

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7 January 2021

p53-dependent apoptosis suppresses tumor growth and progression in vivo

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7 January 2021

Properties of a simian virus 40 mutant T antigen substituted in the hydrophobic region: defective ATPase and oligomerization activities and altered phosphorylation accompany an inability to complex with cellular p53.

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7 January 2021

Requirements for immortalization of primary mouse embryo fibroblasts probed with mutants bearing deletions in the 3' end of SV40 gene A

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7 January 2021

Stabilization of the tumor suppressor p53 during cellular transformation by simian virus 40: influence of viral and cellular factors and biological consequences

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203154

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10602490%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

2 November 2019

0 references

1 reference