Age-related profiling of DNA methylation in CD8+ T cells reveals changes in immune response and transcriptional regulator genes (Q41045051)

26 September 2017

Age-related profiling of DNA methylation in CD8+ T cells reveals changes in immune response and transcriptional regulator genes (English)

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26 September 2017

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6

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26 September 2017

11

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26 September 2017

Silva Kasela

5

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Mario Saare

Mario Saare

7

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Lili Milani

Lili Milani

10

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Andres Metspalu

9

Andres Metspalu

1 reference

26 September 2017

Jaak Vilo

8

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Maia Limbach

3

Maia Limbach

1 reference

26 September 2017

1

Liina Tserel

1 reference

26 September 2017

Raivo Kolde

2

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26 September 2017

Konstantin Tretyakov

4

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26 September 2017

language of work or name

English

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publication date

19 August 2015

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26 September 2017

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26 September 2017

5

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26 September 2017

13107

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Creative Commons Attribution 4.0 International

26 September 2017

start time

19 August 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

limma

Bioconductor limma

2 references

22 June 2022

https://europepmc.org/article/PMC/4541364

based on heuristic

inferred from PubMed Central ID database lookup

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

cites work

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The interface between transcriptional and epigenetic control of effector and memory CD8⁺ T-cell differentiation

26 September 2017

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DNA methylome profiling of human tissues identifies global and tissue-specific methylation patterns

26 September 2017

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Accounting for cellular heterogeneity is critical in epigenome-wide association studies

26 September 2017

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Aging of blood can be tracked by DNA methylation changes at just three CpG sites

26 September 2017

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CpG sites associated with NRP1, NRXN2 and miR-29b-2 are hypomethylated in monocytes during ageing

26 September 2017

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DNA methylation age of human tissues and cell types

26 September 2017

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Human T cell aging and the impact of persistent viral infections

26 September 2017

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26 September 2017

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Transcriptional analysis reveals gender-specific changes in the aging of the human immune system.

26 September 2017

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26 September 2017

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DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape

26 September 2017

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26 September 2017

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Genome-wide methylation profiles reveal quantitative views of human aging rates

26 September 2017

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Differential DNA methylation in purified human blood cells: implications for cell lineage and studies on disease susceptibility

26 September 2017

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Chromatin organizer SATB1 is an important determinant of T-cell differentiation

26 September 2017

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SWAN: Subset-quantile within array normalization for illumina infinium HumanMethylation450 BeadChips

26 September 2017

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DNA methylation arrays as surrogate measures of cell mixture distribution

26 September 2017

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Properties of end-stage human T cells defined by CD45RA re-expression

26 September 2017

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Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population

26 September 2017

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Epigenetic-aging-signature to determine age in different tissues

26 September 2017

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Galectin-1 research in T cell immunity: past, present and future

26 September 2017

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Differentiation-dependent functional and epigenetic landscapes for cytokine genes in virus-specific CD8+ T cells

26 September 2017

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Epigenetic predictor of age

26 September 2017

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Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing

26 September 2017

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26 September 2017

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The stromal cell antigen CD248 (endosialin) is expressed on naive CD8+ human T cells and regulates proliferation

26 September 2017

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Persistent viral infections and immune aging

26 September 2017

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Functional dissection of the granzyme family: cell death and inflammation.

26 September 2017

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Tissue-specific dysregulation of DNA methylation in aging

26 September 2017

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Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains

26 September 2017

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Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer.

26 September 2017

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Global regulator SATB1 recruits beta-catenin and regulates T(H)2 differentiation in Wnt-dependent manner.

26 September 2017

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Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context

26 September 2017

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Conveying glycan information into T-cell homeostatic programs: a challenging role for galectin-1 in inflammatory and tumor microenvironments.

26 September 2017

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Multiparameter flow cytometric analysis of CD4 and CD8 T cell subsets in young and old people

26 September 2017

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The third dimension of gene regulation: organization of dynamic chromatin loopscape by SATB1

26 September 2017

1 reference

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The immune system in extreme longevity

26 September 2017

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T cell development: better living through chromatin

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541364

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541364

Disruption of the BCL11B gene through inv(14)(q11.2q32.31) results in the expression of BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541364

CD27 is required for generation and long-term maintenance of T cell immunity

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541364

Inflamm-aging. An evolutionary perspective on immunosenescence

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541364

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541364

Cytomegalovirus (CMV)-dependent and -independent changes in the aging of the human immune system: a transcriptomic analysis

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541364

Cutting edge: persistently open chromatin at effector gene loci in resting memory CD8+ T cells independent of transcriptional status

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541364

Immunosenescence and Cytomegalovirus: where do we stand after a decade?

14 June 2018

1 reference

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An early T cell lineage commitment checkpoint dependent on the transcription factor Bcl11b

14 June 2018

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14 June 2018

1 reference

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Memory inflation during chronic viral infection is maintained by continuous production of short-lived, functional T cells.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541364

The cytomegalovirus-specific CD4+ T-cell response expands with age and markedly alters the CD4+ T-cell repertoire.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541364

CD27 costimulation contributes substantially to the expansion of functional memory CD8(+) T cells after peptide immunization.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541364

Global DNA methylation remodeling accompanies CD8 T cell effector function.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541364

Gene expression analysis of mTOR pathway: association with human longevity

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541364

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541364

Marked increase with age of type 1 cytokines within memory and effector/cytotoxic CD8+ T cells in humans: a contribution to understand the relationship between inflammation and immunosenescence.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541364

Memory inflation: continuous accumulation of antiviral CD8+ T cells over time.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541364

Methylation of ELOVL2 gene as a new epigenetic marker of age

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4541364

Massive load of functional effector CD4+ and CD8+ T cells against cytomegalovirus in very old subjects

4 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26286994

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The immune risk profile is associated with age and gender: findings from three Swedish population studies of individuals 20-100 years of age

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26286994

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SREP13107

1 reference

26 September 2017

1 reference

26 September 2017

PubMed publication ID

26286994

1 reference