Expression of drug-metabolizing enzymes (Q41082237)

26 September 2017

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title

Expression of drug-metabolizing enzymes (English)

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26 September 2017

Guengerich FP

1

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26 September 2017

Parikh A

series ordinal

2

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26 September 2017

publication date

1 October 1997

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Current Opinion in Biotechnology

26 September 2017

published in

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26 September 2017

volume

8

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26 September 2017

issue

5

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26 September 2017

page(s)

623-628

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Eukaryotic expression systems: a comparison

26 September 2017

cites work

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7 January 2021

Expression of mammalian glutathione S-transferase 5-5 in Salmonella typhimurium TA1535 leads to base-pair mutations upon exposure to dihalomethanes

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7 January 2021

Optimized heterologous expression of the polymorphic human glutathione transferase M1-1 based on silent mutations in the corresponding cDNA.

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7 January 2021

Heterologous expression, purification and characterization of rat class theta glutathione transferase T2-2

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7 January 2021

Forced evolution of glutathione S-transferase to create a more efficient drug detoxication enzyme.

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7 January 2021

Glutathione Transferases with Novel Active Sites Isolated by Phage Display from a Library of Random Mutants

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7 January 2021

Glubodies: randomized libraries of glutathione transferase enzymes

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7 January 2021

Unexpected genetic and structural relationships of a long-forgotten flavoenzyme to NAD(P)H:quinone reductase (DT-diaphorase)

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7 January 2021

Salmonella strains and mammalian cells genetically engineered for expression of sulfotransferases

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7 January 2021

Baculovirus expression and characterization of catalytically active horseradish peroxidase

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7 January 2021

Leukocyte 12-lipoxygenase: expression, purification, and investigation of the role of methionine residues in turnover-dependent inactivation and 5,8,11,14-eicosatetraynoic acid inhibition.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980039-0

7 January 2021

Expression, purification, and characterization of porcine leukocyte 12-lipoxygenase produced in the methylotrophic yeast, Pichia pastoris.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980039-0

7 January 2021

High-level expression of functional rat neuronal nitric oxide synthase in Escherichia coli

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7 January 2021

Neuronal nitric oxide synthase. Expression in Escherichia coli, irreversible inhibition by phenyldiazene, and active site topology.

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7 January 2021

New applications of bacterial systems to problems in toxicology.

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7 January 2021

Purification of functional recombinant P450s from bacteria

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7 January 2021

Expression of bovine 17 alpha-hydroxylase cytochrome P-450 cDNA in nonsteroidogenic (COS 1) cells

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7 January 2021

Monooxygenase activity of Saccharomyces cerevisiae cells transformed with expression plasmids carrying rat cytochrome P-450MC cDNA

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7 January 2021

Expression of a functional 78,000 dalton mammalian flavoprotein, NADPH-cytochrome P-450 oxidoreductase, in Escherichia coli

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7 January 2021

Expression and enzymatic activity of recombinant cytochrome P450 17 alpha-hydroxylase in Escherichia coli

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7 January 2021

Multiple forms of human P450 expressed in Saccharomyces cerevisiae. Systematic characterization and comparison with those of the rat

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7 January 2021

Recombinant human cytochrome P450 1A2 and an N-terminal-truncated form: construction, purification, aggregation properties, and interactions with flavodoxin, ferredoxin, and NADPH-cytochrome P450 reductase

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7 January 2021

Molecular engineering of microsomal P450 2a-4 to a stable, water-soluble enzyme.

1 reference

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7 January 2021

Expression of truncated forms of liver microsomal P450 cytochromes 2B4 and 2E1 in Escherichia coli: influence of NH2-terminal region on localization in cytosol and membranes

1 reference

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7 January 2021

Expression of cytochrome P450 2D6 in Escherichia coli, purification, and spectral and catalytic characterization

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980039-0

7 January 2021

Microsomal P450 2C3 is expressed as a soluble dimer in Escherichia coli following modification of its N-terminus

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980039-0

7 January 2021

Identification of retained N-formylmethionine in bacterial recombinant mammalian cytochrome P450 proteins with the N-terminal sequence MALLLAVFL...: roles of residues 3-5 in retention and membrane topology

1 reference

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7 January 2021

Construction of a human cytochrome P450 1A1: rat NADPH-cytochrome P450 reductase fusion protein cDNA and expression in Escherichia coli, purification, and catalytic properties of the enzyme in bacterial cells and after purification

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980039-0

7 January 2021

Expression, purification, and characterization of a catalytically active human cytochrome P450 1A2:rat NADPH-cytochrome P450 reductase fusion protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980039-0

7 January 2021

Molecular engineering study on electron transfer from NADPH-P450 reductase to rat mitochondrial P450c27 in yeast microsomes

1 reference

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7 January 2021

The interaction of NADPH-P450 reductase with P450: an electrochemical study of the role of the flavin mononucleotide-binding domain.

1 reference

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7 January 2021

Putidaredoxin reductase-putidaredoxin-cytochrome p450cam triple fusion protein. Construction of a self-sufficient Escherichia coli catalytic system.

1 reference

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7 January 2021

CYP3A4 expressed by insect cells infected with a recombinant baculovirus containing both CYP3A4 and human NADPH-cytochrome P450 reductase is catalytically similar to human liver microsomal CYP3A4.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980039-0

7 January 2021

Functional high level expression of cytochrome P450 CYP2D6 using baculoviral expression systems.

1 reference

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7 January 2021

Expression and coupling of human cytochrome P450 2E1 and NADPH-cytochrome P450 oxidoreductase in dual expression and co-infection systems with baculovirus in insect cells

1 reference

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7 January 2021

Stable expression of human cytochrome P450 3A4 in conjunction with human NADPH-cytochrome P450 oxidoreductase in V79 Chinese hamster cells.

1 reference

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7 January 2021

Coexpression of a human P450 (CYP3A4) and P450 reductase generates a highly functional monooxygenase system in Escherichia coli.

1 reference

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7 January 2021

The function of recombinant cytochrome P450s in intact Escherichia coli cells: the 17 alpha-hydroxylation of progesterone and pregnenolone by P450c17.

1 reference

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7 January 2021

Drug metabolism by Escherichia coli expressing human cytochromes P450.

1 reference

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7 January 2021

Expression and characterization of a modified flavin-containing monooxygenase 4 from humans

1 reference

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7 January 2021

Expression of the human UDP-glucuronosyltransferase UGT1*6 in Escherichia coli. Influence of bacterial signal peptides on the production and localization of the recombinant protein.

1 reference

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7 January 2021

Interaction of hepatic microsomal epoxide hydrolase derived from a recombinant baculovirus expression system with an azarene oxide and an aziridine substrate analogue

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7 January 2021

The transmembrane region of microsomal cytochrome P450 identified as the endoplasmic reticulum retention signal

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7 January 2021

The Cytoplasmic and N-terminal Transmembrane Domains of Cytochrome P450 Contain Independent Signals for Retention in the Endoplasmic Reticulum

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980039-0

7 January 2021

Establishment of transgenic mice carrying human fetus-specific CYP3A7.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980039-0

7 January 2021

Use of terfenadine and contraindicated drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980039-0

7 January 2021

Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980039-0

7 January 2021

Human glutathione S-transferase T1-1 enhances mutagenicity of 1,2-dibromoethane, dibromomethane and 1,2,3,4-diepoxybutane in Salmonella typhimurium

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980039-0

7 January 2021

Activation and inactivation of carcinogenic dihaloalkanes and other compounds by glutathione S-transferase 5-5 in Salmonella typhimurium tester strain NM5004.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980039-0

7 January 2021

A new Salmonella typhimurium NM5004 strain expressing rat glutathione S-transferase 5-5: use in detection of genotoxicity of dihaloalkanes using an SOS/umu test system

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980039-0

7 January 2021

Development of an in situ toxicity assay system using recombinant baculoviruses

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980039-0

7 January 2021

Metabolism of chlorofluorocarbons and polybrominated compounds by Pseudomonas putida G786(pHG-2) via an engineered metabolic pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980039-0

7 January 2021

10.1016/S0958-1669(97)80039-0

Identifiers

DOI

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26 September 2017

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