An antagonist for the leukemia inhibitory factor receptor inhibits leukemia inhibitory factor, cardiotrophin-1, ciliary neurotrophic factor, and oncostatin M. (Q41085793)

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scientific article published on October 1997

Language	Label	Description	Also known as
English	An antagonist for the leukemia inhibitory factor receptor inhibits leukemia inhibitory factor, cardiotrophin-1, ciliary neurotrophic factor, and oncostatin M.	scientific article published on October 1997

Statements

scholarly article

1 reference

Europe PubMed Central

26 September 2017

An antagonist for the leukemia inhibitory factor receptor inhibits leukemia inhibitory factor, cardiotrophin-1, ciliary neurotrophic factor, and oncostatin M. (English)

1 reference

Europe PubMed Central

26 September 2017

author name string

A B Vernallis

1

1 reference

Europe PubMed Central

26 September 2017

K R Hudson

2

1 reference

Europe PubMed Central

26 September 2017

J K Heath

3

1 reference

Europe PubMed Central

26 September 2017

language of work or name

0 references

publication date

1 October 1997

1 reference

Europe PubMed Central

26 September 2017

number of pages

6

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based on heuristic

inferred from page(s)

Journal of Biological Chemistry

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Europe PubMed Central

26 September 2017

272

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Europe PubMed Central

26 September 2017

43

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Europe PubMed Central

26 September 2017

26947-26952

1 reference

Europe PubMed Central

26 September 2017

Multiple regions within the cytoplasmic domains of the leukemia inhibitory factor receptor and gp130 cooperate in signal transduction in hepatic and neuronal cells

1 reference

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Proliferative responses and binding properties of hematopoietic cells transfected with low-affinity receptors for leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor

1 reference

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21 January 2018

Cardiotrophin-1. Biological activities and binding to the leukemia inhibitory factor receptor/gp130 signaling complex

1 reference

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21 January 2018

LIFR beta and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor

1 reference

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21 January 2018

The alpha component of the CNTF receptor is required for signaling and defines potential CNTF targets in the adult and during development

1 reference

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21 January 2018

Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

1 reference

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21 January 2018

Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components

1 reference

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21 January 2018

STAT3 activation by cytokines utilizing gp130 and related transducers involves a secondary modification requiring an H7-sensitive kinase

1 reference

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21 January 2018

Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway

1 reference

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21 January 2018

The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family

1 reference

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21 January 2018

Cytokine receptor signalling

1 reference

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21 January 2018

STATs: signal transducers and activators of transcription

1 reference

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21 January 2018

Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation

1 reference

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21 January 2018

Molecular basis of the soluble and membrane-bound forms of the murine leukemia inhibitory factor receptor alpha-chain. Expression in normal, gestating, and leukemia inhibitory factor nullizygous mice.

1 reference

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21 January 2018

Gp130, a shared signal transducing receptor component for hematopoietic and neuropoietic cytokines

1 reference

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21 January 2018

Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth

1 reference

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21 January 2018

Leukemia inhibitory factor is expressed in cartilage and synovium and can contribute to the pathogenesis of arthritis

1 reference

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21 January 2018

Injury-induced regulation of ciliary neurotrophic factor mRNA in the adult rat brain.

1 reference

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21 January 2018

Major changes in the expression of the mRNAs for cholinergic differentiation factor/leukemia inhibitory factor and its receptor after injury to adult peripheral nerves and ganglia

1 reference

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21 January 2018

Ciliary neurotropic factor, interleukin 11, leukemia inhibitory factor, and oncostatin M are growth factors for human myeloma cell lines using the interleukin 6 signal transducer gp130

1 reference

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21 January 2018

The IL-6 signal transducer, gp130: an oncostatin M receptor and affinity converter for the LIF receptor

1 reference

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21 January 2018

The basics of basal transcription by RNA polymerase II.

1 reference

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21 January 2018

Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system

1 reference

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21 January 2018

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.43.26947

21 January 2018

Nonradioactive receptor binding assay for ciliary neurotrophic factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.43.26947

21 January 2018

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1 reference

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21 January 2018

Are LIF and related cytokines functionally equivalent?

1 reference

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21 January 2018

Human IL-3 (multi-CSF): identification by expression cloning of a novel hematopoietic growth factor related to murine IL-3.

1 reference

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21 January 2018

Detection of receptors for interleukin-6, interleukin-11, leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor in bone marrow stromal/osteoblastic cells

1 reference

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21 January 2018

STAT proteins participate in the regulation of the vasoactive intestinal peptide gene by the ciliary neurotrophic factor family of cytokines

1 reference

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21 January 2018

Vasoactive intestinal peptide: autocrine growth factor in neuroblastoma

1 reference

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21 January 2018

Rational design of potent antagonists to the human growth hormone receptor

1 reference

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21 January 2018

Design of human interleukin-4 antagonists inhibiting interleukin-4-dependent and interleukin-13-dependent responses in T-cells and B-cells with high efficiency

1 reference

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21 January 2018

Specific human granulocyte-macrophage colony-stimulating factor antagonists.

1 reference

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21 January 2018

Combining two mutations of human interleukin-6 that affect gp130 activation results in a potent interleukin-6 receptor antagonist on human myeloma cells

1 reference

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21 January 2018

Identification of ciliary neurotrophic factor (CNTF) residues essential for leukemia inhibitory factor receptor binding and generation of CNTF receptor antagonists.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.43.26947

21 January 2018

Development of an interleukin (IL) 6 receptor antagonist that inhibits IL-6-dependent growth of human myeloma cells.

1 reference

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21 January 2018

A murine interleukin-4 antagonistic mutant protein completely inhibits interleukin-4-induced cell proliferation, differentiation, and signal transduction

1 reference

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21 January 2018

Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.43.26947

21 January 2018

STAT proteins are activated by ciliary neurotrophic factor in cells of central nervous system origin

1 reference

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21 January 2018

An interleukin 4 (IL-4) mutant protein inhibits both IL-4 or IL-13-induced human immunoglobulin G4 (IgG4) and IgE synthesis and B cell proliferation: support for a common component shared by IL-4 and IL-13 receptors

1 reference

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21 January 2018

Essential function of LIF receptor in motor neurons

1 reference

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21 January 2018

Expression of transcripts of interleukin-6 and related cytokines by human breast tumors, breast cancer cells, and adipose stromal cells

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21 January 2018

Leukaemia inhibitory factor and interleukin 6 are expressed at very low levels in the normal adult mouse and are induced by inflammation

1 reference

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21 January 2018

High circulating leukaemia inhibitory factor (LIF) in patients with giant cell arteritis: independent regulation of LIF and IL-6 under corticosteroid therapy

1 reference

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Leukemia inhibitory factor and interleukin-6 are produced by diseased and regenerating skeletal muscle

1 reference

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Neurotrophic factor receptors and their signal transduction capabilities in rat astrocytes

1 reference

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Regulation of vasoactive intestinal peptide expression in sympathetic neurons in culture and after axotomy: the role of cholinergic differentiation factor/leukemia inhibitory factor

1 reference

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21 January 2018

Leukaemia inhibitory factor induced in the sciatic nerve after axotomy is involved in the induction of galanin in sensory neurons

1 reference

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21 January 2018

Involvement of leukemia inhibitory factor in the increases in galanin and vasoactive intestinal peptide mRNA and the decreases in neuropeptide Y and tyrosine hydroxylase mRNA in sympathetic neurons after axotomy

1 reference

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21 January 2018

Released form of CNTF receptor alpha component as a soluble mediator of CNTF responses

1 reference

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21 January 2018

Leukaemia inhibitory factor is retrogradely transported by a distinct population of adult rat sensory neurons: co-localization with trkA and other neurochemical markers

1 reference

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21 January 2018

Characterization of the receptor binding sites of human leukemia inhibitory factor and creation of antagonists

1 reference

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21 January 2018

A consensus sequence for substrate hydrolysis by rhinovirus 3C proteinase

1 reference

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21 January 2018

Oncostatin M regulates VIP expression in a human neuroblastoma cell line.

1 reference

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21 January 2018

Identifiers

10.1074/JBC.272.43.26947

1 reference

Europe PubMed Central

26 September 2017

1 reference

Europe PubMed Central

26 September 2017

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