Donor CD19 CAR T cells exert potent graft-versus-lymphoma activity with diminished graft-versus-host activity. (Q41131801)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067900%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

title

Donor CD19 CAR T cells exert potent graft-versus-lymphoma activity with diminished graft-versus-host activity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067900%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

1

1 reference

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5 April 2020

Marco L Davila

4

1 reference

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5 April 2020

Jarrod Dudakov

18

1 reference

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5 April 2020

Ana Carolina F Motta

21

1 reference

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5 April 2020

8

Fabiana Perna

1 reference

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5 April 2020

author name string

Melody Smith

2

1 reference

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5 April 2020

Scott E James

3

1 reference

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5 April 2020

Enrico Velardi

5

1 reference

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5 April 2020

Kimon V Argyropoulos

6

1 reference

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5 April 2020

Gertrude Gunset

7

1 reference

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5 April 2020

Fabiana M Kreines

9

1 reference

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5 April 2020

Emily R Levy

10

1 reference

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5 April 2020

Sophie Lieberman

11

1 reference

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5 April 2020

Hillary V Jay

12

1 reference

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5 April 2020

Andrea Z Tuckett

13

1 reference

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5 April 2020

Johannes L Zakrzewski

14

1 reference

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5 April 2020

Lisa Tan

15

1 reference

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5 April 2020

Lauren F Young

16

1 reference

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5 April 2020

Kate Takvorian

17

1 reference

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5 April 2020

Robert R Jenq

19

1 reference

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5 April 2020

Alan M Hanash

20

1 reference

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5 April 2020

George F Murphy

22

1 reference

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5 April 2020

Chen Liu

23

1 reference

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5 April 2020

Andrea Schietinger

24

1 reference

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5 April 2020

Michel Sadelain

25

1 reference

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5 April 2020

Marcel R M van den Brink

26

1 reference

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5 April 2020

language of work or name

English

0 references

publication date

9 January 2017

1 reference

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5 April 2020

1 reference

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5 April 2020

volume

23

1 reference

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5 April 2020

issue

2

1 reference

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5 April 2020

page(s)

242-249

1 reference

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describes a project that uses

5 April 2020

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/5528161

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/nm.4258

0 references

cites work

Allogeneic T Cells That Express an Anti-CD19 Chimeric Antigen Receptor Induce Remissions of B-Cell Malignancies That Progress After Allogeneic Hematopoietic Stem-Cell Transplantation Without Causing Graft-Versus-Host Disease

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Murine allogeneic CD19 CAR T cells harbor potent antileukemic activity but have the potential to mediate lethal GVHD.

27 September 2017

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Structural Design of Engineered Costimulation Determines Tumor Rejection Kinetics and Persistence of CAR T Cells

27 September 2017

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CAR therapy: the CD19 paradigm

27 September 2017

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4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors

27 September 2017

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Going viral: chimeric antigen receptor T-cell therapy for hematological malignancies

27 September 2017

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T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial

27 September 2017

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Chimeric antigen receptor T cells for sustained remissions in leukemia

27 September 2017

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Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor

27 September 2017

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Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia

27 September 2017

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Donor-derived CD19-targeted T cells cause regression of malignancy persisting after allogeneic hematopoietic stem cell transplantation

27 September 2017

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Infusion of donor-derived CD19-redirected virus-specific T cells for B-cell malignancies relapsed after allogeneic stem cell transplant: a phase 1 study

27 September 2017

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PLZF confers effector functions to donor T cells that preserve graft-versus-tumor effects while attenuating GVHD

27 September 2017

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Adoptively transferred TRAIL+ T cells suppress GVHD and augment antitumor activity

27 September 2017

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CD19 CAR-targeted T cells induce long-term remission and B Cell Aplasia in an immunocompetent mouse model of B cell acute lymphoblastic leukemia.

27 September 2017

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The basic principles of chimeric antigen receptor design

27 September 2017

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Chimeric antigen receptor-modified T cells for acute lymphoid leukemia

27 September 2017

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Donor lymphocyte infusion for relapsed hematological malignancies after allogeneic hematopoietic cell transplantation: prognostic relevance of the initial CD3+ T cell dose

27 September 2017

1 reference

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CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia

27 September 2017

1 reference

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Progenitor and terminal subsets of CD8+ T cells cooperate to contain chronic viral infection.

27 September 2017

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Regulation of intestinal inflammation by microbiota following allogeneic bone marrow transplantation

27 September 2017

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Protein L: a novel reagent for the detection of chimeric antigen receptor (CAR) expression by flow cytometry

27 September 2017

1 reference

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Donor B-cell alloantibody deposition and germinal center formation are required for the development of murine chronic GVHD and bronchiolitis obliterans

27 September 2017

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Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias

27 September 2017

1 reference

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T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia

27 September 2017

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27 September 2017

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Adoptive transfer of syngeneic T cells transduced with a chimeric antigen receptor that recognizes murine CD19 can eradicate lymphoma and normal B cells

27 September 2017

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Antibody-mediated B-cell depletion before adoptive immunotherapy with T cells expressing CD20-specific chimeric T-cell receptors facilitates eradication of leukemia in immunocompetent mice

27 September 2017

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Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells

27 September 2017

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B cells and transplantation: an educational resource

27 September 2017

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Retroviral transduction of murine primary T lymphocytes

27 September 2017

1 reference

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Peripheral CD8+ T cell tolerance to self-proteins is regulated proximally at the T cell receptor.

27 September 2017

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Linear models and empirical bayes methods for assessing differential expression in microarray experiments

27 September 2017

1 reference

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Exploration, normalization, and summaries of high density oligonucleotide array probe level data

27 September 2017

1 reference

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Adoptive immunotherapy: engineering T cell responses as biologic weapons for tumor mass destruction

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528161

Targeting tumours with genetically enhanced T lymphocytes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528161

T cells require TRAIL for optimal graft-versus-tumor activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528161

B lymphocyte-specific, Cre-mediated mutagenesis in mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528161

Effects of retroviral vector design on expression of human adenosine deaminase in murine bone marrow transplant recipients engrafted with genetically modified cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528161

Rescued tolerant CD8 T cells are preprogrammed to reestablish the tolerant state

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528161

Eradication of systemic B-cell tumors by genetically targeted human T lymphocytes co-stimulated by CD80 and interleukin-15.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528161

Incomplete block of B cell development and immunoglobulin production in mice carrying the muMT mutation on the BALB/c background.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528161

Allograft rejection in a new allospecific CD4+ TCR transgenic mouse

19 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28067900

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NM.4258

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067900%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067900%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

PubMed publication ID

28067900

1 reference