Constitutive activation of protein kinase B and phosphorylation of p47phox by a membrane-targeted phosphoinositide 3-kinase (Q41160740)

27 September 2017

Constitutive activation of protein kinase B and phosphorylation of p47phox by a membrane-targeted phosphoinositide 3-kinase (English)

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27 September 2017

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3

Hemmings BA

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27 September 2017

Didichenko SA

1

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27 September 2017

Tilton B

series ordinal

2

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27 September 2017

Ballmer-Hofer K

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4

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27 September 2017

Thelen M

series ordinal

5

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27 September 2017

language of work or name

English

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publication date

1 October 1996

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27 September 2017

8

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inferred from page(s)

published in

Current Biology

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27 September 2017

6

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27 September 2017

1271-1278

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27 September 2017

10

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Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphosphate: a new intracellular signalling system?

27 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Phosphatidylinositol-3-OH kinase as a direct target of Ras

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Phosphatidylinositol (3,4,5)P3 interacts with SH2 domains and modulates PI 3-kinase association with tyrosine-phosphorylated proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Wortmannin, an inhibitor of phosphoinositide 3-kinase, inhibits transcytosis in polarized epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Wortmannin binds specifically to 1-phosphatidylinositol 3-kinase while inhibiting guanine nucleotide-binding protein-coupled receptor signaling in neutrophil leukocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Purification and characterization of bovine brain type I phosphatidylinositol kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

A short sequence in the p60src N terminus is required for p60src myristylation and membrane association and for cell transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Regulation by phosphorylation of reversible association of a myristoylated protein kinase C substrate with the plasma membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

A CAAX or a CAAL motif and a second signal are sufficient for plasma membrane targeting of ras proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Expression and characterization of calcium-myristoyl switch proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

The biochemical basis of the NADPH oxidase of phagocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

The phosphorylation targets of p47phox, a subunit of the respiratory burst oxidase. Functions of the individual target serines as evaluated by site-directed mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

The respiratory burst oxidase and the molecular genetics of chronic granulomatous disease

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Phosphorylation of the respiratory burst oxidase subunit p47phox as determined by two-dimensional phosphopeptide mapping. Phosphorylation by protein kinase C, protein kinase A, and a mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

The 47-kDa protein involved in the NADPH:O2 oxidoreductase activity of human neutrophils is phosphorylated by cyclic AMP-dependent protein kinase without induction of a respiratory burst

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Regulation of human leukocyte p21-activated kinases through G protein--coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

FMLP activates Ras and Raf in human neutrophils. Potential role in activation of MAP kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Interleukin-8 regulation of the Ras/Raf/mitogen-activated protein kinase pathway in human neutrophils

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

GM-1, a clone of the monoblastic phagocyte U937 that expresses a large respiratory burst capacity upon activation with interferon-gamma.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Pathway of phosphatidylinositol(3,4,5)-trisphosphate synthesis in activated neutrophils

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

PI 3-kinase is a dual specificity enzyme: autoregulation by an intrinsic protein-serine kinase activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Differential roles of PI3-kinase and Kit tyrosine 821 in Kit receptor-mediated proliferation, survival and cell adhesion in mast cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Studies with wortmannin suggest a role for phosphatidylinositol 3-kinase in the activation of glycogen synthase and mitogen-activated protein kinase by insulin in rat adipocytes: comparison of insulin and protein kinase C modulators

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Ras-dependent activation of MAP kinase pathway mediated by G-protein beta gamma subunits.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Distinct pathways of Gi- and Gq-mediated mitogen-activated protein kinase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Regulation of the phagocyte respiratory burst by small GTP-binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Antagonists of phosphatidylinositol 3-kinase block activation of several novel protein kinases in neutrophils

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Purification and characterization of a phosphatidylinositol 3-kinase complex from bovine brain by using phosphopeptide affinity columns

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Inhibition of the phagocytosis-induced respiratory burst by the fungal metabolite wortmannin and some analogues

1 reference

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7 January 2021

Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Tumor necrosis factor alpha modifies agonist-dependent responses in human neutrophils by inducing the synthesis and myristoylation of a specific protein kinase C substrate

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

An inositol tetrakisphosphate-containing phospholipid in activated neutrophils

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

Alkaline O→N-transacylation. A new method for the quantitative deacylation of phospholipids

1 reference

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7 January 2021

A comparison of post-receptor signal transduction events in Jurkat cells transfected with either IL-8R1 or IL-8R2. Chemokine mediated activation of p42/p44 MAP-kinase (ERK-2).

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2970713-6

7 January 2021

10.1016/S0960-9822(02)70713-6

Identifiers

DOI

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27 September 2017

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