Aging-dependent functional alterations of mitochondrial DNA (mtDNA) from human fibroblasts transferred into mtDNA-less cells (Q41186102)

28 September 2017

title

Aging-dependent functional alterations of mitochondrial DNA (mtDNA) from human fibroblasts transferred into mtDNA-less cells (English)

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28 September 2017

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Laderman KA

1

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28 September 2017

Penny JR

2

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28 September 2017

Mazzucchelli F

3

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28 September 2017

Bresolin N

4

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28 September 2017

Scarlato G

5

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28 September 2017

Attardi G

6

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28 September 2017

language of work or name

English

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publication date

1 July 1996

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Journal of Biological Chemistry

28 September 2017

published in

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28 September 2017

volume

271

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28 September 2017

issue

27

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28 September 2017

page(s)

15891-15897

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Aging: a theory based on free radical and radiation chemistry

28 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

Mitochondrial role in cell aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

Oxidants, antioxidants, and the degenerative diseases of aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

An update on the mitochondrial-DNA mutation hypothesis of cell aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

Oxidative damage and mitochondrial decay in aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

Rapid evolution of animal mitochondrial DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

Age-dependent impairment of mitochondrial function in primate brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

Detection of a specific mitochondrial DNA deletion in tissues of older humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

Multiple mitochondrial DNA deletions in an elderly human individual

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

Studies of sequence heterogeneity of mitochondrial DNA from rat and mouse tissues: evidence for an increased frequency of deletions/additions with aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

Normal oxidative damage to mitochondrial and nuclear DNA is extensive

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

Age-associated accumulation of 8-hydroxydeoxyguanosine in mitochondrial DNA of human diaphragm

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

Diseases of the mitochondrial DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

MELAS mutation in mtDNA binding site for transcription termination factor causes defects in protein synthesis and in respiration but no change in levels of upstream and downstream mature transcripts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

In vitro genetic transfer of protein synthesis and respiration defects to mitochondrial DNA-less cells with myopathy-patient mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

Introduction of disease-related mitochondrial DNA deletions into HeLa cells lacking mitochondrial DNA results in mitochondrial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

Cytoplasmic transfer of the mtDNA nt 8993 T-->G (ATP6) point mutation associated with Leigh syndrome into mtDNA-less cells demonstrates cosegregation with a decrease in state III respiration and ADP/O ratio

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

Efficient selection and characterization of mutants of a human cell line which are defective in mitochondrial DNA-encoded subunits of respiratory NADH dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

Variation among human 28S ribosomal RNA genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

Complementation of mutant and wild-type human mitochondrial DNAs coexisting since the mutation event and lack of complementation of DNAs introduced separately into a cell within distinct organelles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

Relationship of genotype to phenotype in fibroblast-derived transmitochondrial cell lines carrying the 3243 mutation associated with the MELAS encephalomyopathy: shift towards mutant genotype and role of mtDNA copy number

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

Mitochondrial genetics: a paradigm for aging and degenerative diseases?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.27.15891

21 January 2018

Identifiers

DOI

10.1074/JBC.271.27.15891

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28 September 2017

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