A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis (Q41201382)

28 September 2017

title

A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis (English)

1 reference

genome-wide association study

28 September 2017

main subject

0 references

author

Andrew McQuillin

12

1 reference

28 September 2017

33

1 reference

28 September 2017

38

1 reference

28 September 2017

41

1 reference

28 September 2017

48

1 reference

28 September 2017

11

Marcella Rietschel

1 reference

28 September 2017

Eric Trépo

3

0 references

Mario Brosch

Mario Brosch

7

0 references

Michael Nothnagel

Michael Nothnagel

39

0 references

Hans Dieter Nischalke

Hans Dieter Nischalke

6

0 references

Florian Eyer

Florian Eyer

35

0 references

Sebastian Zeissig

23

Sebastian Zeissig

1 reference

28 September 2017

34

Julia Mayerle

1 reference

28 September 2017

15

Stefan Schreiber

1 reference

28 September 2017

42

Andre Franke

1 reference

28 September 2017

8

Jonas Rosendahl

1 reference

28 September 2017

21

Renate Schmelz

1 reference

28 September 2017

29

Frank Lammert

1 reference

28 September 2017

44

Claus Hellerbrand

1 reference

28 September 2017

10

Monika Ridinger

1 reference

28 September 2017

25

Norbert Wodarz

1 reference

28 September 2017

14

Falk Kiefer

1 reference

28 September 2017

28

Christoph Sarrazin

1 reference

28 September 2017

31

Pierre Deltenre

1 reference

28 September 2017

36

Clemens Schafmayer

1 reference

28 September 2017

19

Elmar Aigner

1 reference

28 September 2017

20

Christian Datz

1 reference

28 September 2017

2

Felix Stickel

1 reference

28 September 2017

32

Henry Völzke

1 reference

28 September 2017

16

Wolfgang Lieb

1 reference

28 September 2017

37

Sven Cichon

1 reference

28 September 2017

Stephan Buch

1

1 reference

28 September 2017

Michael Way

4

1 reference

28 September 2017

Alexander Herrmann

5

1 reference

28 September 2017

Thomas Berg

9

1 reference

28 September 2017

Josef Frank

13

1 reference

28 September 2017

Michael Soyka

17

1 reference

28 September 2017

Nasser Semmo

18

1 reference

28 September 2017

Stefan Brückner

22

1 reference

28 September 2017

Anna-Magdalena Stephan

24

1 reference

28 September 2017

Jacques Devière

26

1 reference

28 September 2017

Nicolas Clumeck

27

1 reference

28 September 2017

Thierry Gustot

30

1 reference

28 September 2017

David Ellinghaus

40

1 reference

28 September 2017

Steffen Zopf

43

1 reference

28 September 2017

Christophe Moreno

45

1 reference

28 September 2017

Denis Franchimont

46

1 reference

28 September 2017

Marsha Y Morgan

47

1 reference

28 September 2017

language of work or name

English

0 references

publication date

19 October 2015

1 reference

28 September 2017

1 reference

28 September 2017

volume

47

1 reference

28 September 2017

issue

12

1 reference

28 September 2017

page(s)

1443-1448

1 reference

describes a project that uses

28 September 2017

genome-wide association study

1 reference

https://scigraph.springernature.com/pub.10.1038/ng.3417

inferred from title

exact match

0 references

cites work

Global burden of alcoholic liver diseases

1 reference

Liver transplantation for alcoholic liver disease in Europe: a study from the ELTR (European Liver Transplant Registry).

21 January 2018

1 reference

Evidence of genetic predisposition to alcoholic cirrhosis and psychosis: twin concordances for alcoholism and its biological end points by zygosity among male veterans

21 January 2018

1 reference

Genetic predisposition to organ-specific endpoints of alcoholism

21 January 2018

1 reference

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

21 January 2018

1 reference

Variant in PNPLA3 is associated with alcoholic liver disease

21 January 2018

1 reference

PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells

21 January 2018

1 reference

Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis

21 January 2018

1 reference

A flexible and accurate genotype imputation method for the next generation of genome-wide association studies

21 January 2018

1 reference

Identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue

21 January 2018

1 reference

Systematic review with meta-analysis: the I148M variant of patatin-like phospholipase domain-containing 3 gene (PNPLA3) is significantly associated with alcoholic liver cirrhosis.

21 January 2018

1 reference

PNPLA3 Gene Polymorphism Is Associated With Predisposition to and Severity of Alcoholic Liver Disease.

21 January 2018

1 reference

Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease

21 January 2018

1 reference

Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection

21 January 2018

1 reference

A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease

21 January 2018

1 reference

Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis

21 January 2018

1 reference

Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci

21 January 2018

1 reference

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

21 January 2018

1 reference

A genome-wide association study of alcohol dependence

21 January 2018

1 reference

Integrating GWASs and human protein interaction networks identifies a gene subnetwork underlying alcohol dependence

21 January 2018

1 reference

Genome-wide association study of alcohol dependence

21 January 2018

1 reference

21 January 2018

Genetics and alcoholism

1 reference

Do alcohol-metabolizing enzyme gene polymorphisms increase the risk of alcoholism and alcoholic liver disease?

21 January 2018

1 reference

A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis

21 January 2018

1 reference

Lysophospholipid acyltransferases and arachidonate recycling in human neutrophils

21 January 2018

1 reference

Reverse reaction of lysophosphatidylinositol acyltransferase. Functional reconstitution of coenzyme A-dependent transacylation system

21 January 2018

1 reference

The L-α-lysophosphatidylinositol/GPR55 system and its potential role in human obesity

21 January 2018

1 reference

Endocannabinoids in liver disease

21 January 2018

1 reference

Cannabinoid receptor type I modulates alcohol-induced liver fibrosis

21 January 2018

1 reference

Transmembrane 6 superfamily member 2 gene variant disentangles nonalcoholic steatohepatitis from cardiovascular disease.

21 January 2018

1 reference

Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits

21 January 2018

1 reference

A common polymorphism in the NCAN gene is associated with hepatocellular carcinoma in alcoholic liver disease

21 January 2018

1 reference

Immediate listing for liver transplantation versus standard care for Child-Pugh stage B alcoholic cirrhosis: a randomized trial

21 January 2018

1 reference

LocusZoom: regional visualization of genome-wide association scan results

21 January 2018

1 reference

Quantifying heterogeneity in a meta-analysis

21 January 2018

1 reference

Genetic variants in or near ADH1B and ADH1C affect susceptibility to alcohol dependence in a British and Irish population.

21 January 2018

1 reference

Marked 25-hydroxyvitamin D deficiency is associated with poor prognosis in patients with alcoholic liver disease

21 January 2018

1 reference

Alcoholic liver disease: pathologic, pathogenetic and clinical aspects

21 January 2018

1 reference

Assessment of asymptomatic liver fibrosis in alcoholic patients using fibroscan: prospective comparison with seven non-invasive laboratory tests.

21 January 2018

1 reference

Simultaneous genotype calling and haplotype phasing improves genotype accuracy and reduces false-positive associations for genome-wide association studies

21 January 2018

1 reference

Principal components analysis corrects for stratification in genome-wide association studies

21 January 2018

1 reference

fcGENE: a versatile tool for processing and transforming SNP datasets

21 January 2018

1 reference

Artifact due to differential error when cases and controls are imputed from different platforms

21 January 2018

1 reference

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

21 January 2018

1 reference

Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians

21 January 2018

1 reference

Burden of liver disease in the United States: summary of a workshop

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26482880

12 December 2020

inferred from PubMed ID database lookup

Determinants of progression to cirrhosis or fibrosis in pure alcoholic fatty liver

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26482880

12 December 2020

inferred from PubMed ID database lookup

TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-alcoholic fatty liver disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26482880

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NG.3417

1 reference

Dimensions Publication ID

28 September 2017

1032649546

0 references

1 reference