Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis (Q34675058)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24917523%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

title

Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis (English)

1 reference

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20 March 2020

1 reference

3

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20 March 2020

8

Helen H Hobbs

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20 March 2020

7

Jonathan C Cohen

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20 March 2020

author name string

Eriks Smagris

1

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20 March 2020

Soumik BasuRay

2

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20 March 2020

Yongcheng Huang

4

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20 March 2020

Ka-man V Lai

5

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20 March 2020

Jesper Gromada

6

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20 March 2020

language of work or name

English

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publication date

1 October 2014

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20 March 2020

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20 March 2020

volume

61

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20 March 2020

issue

1

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20 March 2020

page(s)

108-118

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describes a project that uses

20 March 2020

ImageJ

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11 June 2022

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based on heuristic

inferred from PubMed Central ID database lookup

cites work

PNPLA3 I148M polymorphism and progressive liver disease

1 reference

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Evolving frequency and outcomes of liver transplantation based on etiology of liver disease

7 July 2018

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Role of patatin-like phospholipase domain-containing 3 on lipid-induced hepatic steatosis and insulin resistance in rats

7 July 2018

1 reference

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Chronic overexpression of PNPLA3I148M in mouse liver causes hepatic steatosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262735

Paradoxical lower serum triglyceride levels and higher type 2 diabetes mellitus susceptibility in obese individuals with the PNPLA3 148M variant

7 July 2018

1 reference

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Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase

7 July 2018

1 reference

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PNPLA3 gene-by-visceral adipose tissue volume interaction and the pathogenesis of fatty liver disease: the NHLBI family heart study

7 July 2018

1 reference

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Expression and characterization of a PNPLA3 protein isoform (I148M) associated with nonalcoholic fatty liver disease

7 July 2018

1 reference

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Human fatty liver disease: old questions and new insights

7 July 2018

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Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits

7 July 2018

1 reference

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Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome

7 July 2018

1 reference

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Increased hepatic fat in overweight Hispanic youth influenced by interaction between genetic variation in PNPLA3 and high dietary carbohydrate and sugar consumption

7 July 2018

1 reference

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A common variant in the patatin-like phospholipase 3 gene (PNPLA3) is associated with fatty liver disease in obese children and adolescents

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262735

Patatin-like phospholipase domain-containing 3/adiponutrin deficiency in mice is not associated with fatty liver disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262735

PNPLA3 variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease

7 July 2018

1 reference

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Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection

7 July 2018

1 reference

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A feed-forward loop amplifies nutritional regulation of PNPLA3

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262735

A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262735

Epidemiology and natural history of non-alcoholic steatohepatitis

7 July 2018

1 reference

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Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene

7 July 2018

1 reference

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Deletion of ELOVL5 leads to fatty liver through activation of SREBP-1c in mice

7 July 2018

1 reference

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Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

7 July 2018

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Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome

7 July 2018

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Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity

7 July 2018

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The clinical features, diagnosis and natural history of nonalcoholic fatty liver disease

7 July 2018

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Overexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesis

7 July 2018

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A simple method for the isolation and purification of total lipides from animal tissues

7 July 2018

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SREBPs: transcriptional mediators of lipid homeostasis

7 July 2018

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The global NAFLD epidemic

7 July 2018

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Recombinant PNPLA3 protein shows triglyceride hydrolase activity and its I148M mutation results in loss of function

21 January 2018

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A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans

21 January 2018

1 reference

Non-alcoholic fatty liver disease as an independent manifestation of the metabolic syndrome: Results of a US national survey in three ethnic groups

21 January 2018

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21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/24917523

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/HEP.27242

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24917523%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

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20 March 2020

1 reference

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