mRNA-transfected dendritic cell vaccine in combination with metronomic cyclophosphamide as treatment for patients with advanced malignant melanoma. (Q41297982)

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English	mRNA-transfected dendritic cell vaccine in combination with metronomic cyclophosphamide as treatment for patients with advanced malignant melanoma.	scientific article

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25 March 2020

mRNA-transfected dendritic cell vaccine in combination with metronomic cyclophosphamide as treatment for patients with advanced malignant melanoma (English)

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25 March 2020

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Inge Marie Svane

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25 March 2020

Troels Holz Borch

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25 March 2020

Mads Hald Andersen

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25 March 2020

Per thor Straten

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25 March 2020

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Lotte Engell-Noerregaard

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25 March 2020

Trine Zeeberg Iversen

3

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25 March 2020

Eva Ellebaek

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publication date

8 July 2016

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25 March 2020

5

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25 March 2020

e1207842

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25 March 2020

9

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25 March 2020

Phase II Study of Autologous Monocyte-Derived mRNA Electroporated Dendritic Cells (TriMixDC-MEL) Plus Ipilimumab in Patients With Pretreated Advanced Melanoma

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1 October 2017

Mismatch in epitope specificities between IFNγ inflamed and uninflamed conditions leads to escape from T lymphocyte killing in melanoma.

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1 October 2017

A randomized phase II clinical trial of personalized peptide vaccination with metronomic low-dose cyclophosphamide in patients with metastatic castration-resistant prostate cancer

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T cells are functionally not impaired in AML: increased PD-1 expression is only seen at time of relapse and correlates with a shift towards the memory T cell compartment.

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1 October 2017

Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma

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1 October 2017

Metronomic cyclophosphamide enhances HPV16E7 peptide vaccine induced antigen-specific and cytotoxic T-cell mediated antitumor immune response

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1 October 2017

Pooled Analysis of Long-Term Survival Data From Phase II and Phase III Trials of Ipilimumab in Unresectable or Metastatic Melanoma

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1 October 2017

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1 October 2017

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1 October 2017

Inhibitory Receptor Expression Depends More Dominantly on Differentiation and Activation than "Exhaustion" of Human CD8 T Cells

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1 October 2017

T cells from CLL patients exhibit features of T-cell exhaustion but retain capacity for cytokine production.

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1 October 2017

Adoptive cell therapy with autologous tumor infiltrating lymphocytes and low-dose Interleukin-2 in metastatic melanoma patients

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1 October 2017

Dendritic cell-based vaccination in metastatic melanoma patients: phase II clinical trial

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1 October 2017

Cellular based cancer vaccines: type 1 polarization of dendritic cells.

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1 October 2017

The secret ally: immunostimulation by anticancer drugs

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1 October 2017

Therapeutic vaccination with an autologous mRNA electroporated dendritic cell vaccine in patients with advanced melanoma.

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1 October 2017

Multicenter phase II study of matured dendritic cells pulsed with melanoma cell line lysates in patients with advanced melanoma

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1 October 2017

Response definition criteria for ELISPOT assays revisited

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1 October 2017

Dendritic cell vaccination combined with CTLA4 blockade in patients with metastatic melanoma

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1 October 2017

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1 October 2017

Phase I/II trial of melanoma therapy with dendritic cells transfected with autologous tumor-mRNA.

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Intranodal vaccination with mRNA-optimized dendritic cells in metastatic melanoma patients

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19 August 2018

Inhibition of CD4(+)25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide

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19 August 2018

Vaccination with p53-peptide-pulsed dendritic cells, of patients with advanced breast cancer: report from a phase I study.

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19 August 2018

Synergistic effect of metronomic dosing of cyclophosphamide combined with specific antitumor immunotherapy in a murine melanoma model.

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19 August 2018

Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients

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21 January 2018

Vaccination with mRNA-Electroporated Dendritic Cells Induces Robust Tumor Antigen-Specific CD4+ and CD8+ T Cells Responses in Stage III and IV Melanoma Patients

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21 January 2018

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4 November 2018

Immunomonitoring Tumor-Specific T Cells in Delayed-Type Hypersensitivity Skin Biopsies After Dendritic Cell Vaccination Correlates With Clinical Outcome

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21 January 2018

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12 December 2020

based on heuristic

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High immunogenic potential of p53 mRNA-transfected dendritic cells in patients with primary breast cancer

1 reference

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12 December 2020

based on heuristic

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Inhibitory effect of RNA pool complexity on stimulatory capacity of RNA-pulsed dendritic cells

1 reference

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12 December 2020

based on heuristic

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HLA-Restricted CTL That Are Specific for the Immune Checkpoint Ligand PD-L1 Occur with High Frequency in Cancer Patients

1 reference

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12 December 2020

based on heuristic

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Metastatic melanoma patients treated with dendritic cell vaccination, Interleukin-2 and metronomic cyclophosphamide: results from a phase II trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/27757300

12 December 2020

based on heuristic

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alpha-type-1 polarized dendritic cells: a novel immunization tool with optimized CTL-inducing activity

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on mRNA Electroporation of Immature and Mature Dendritic Cells: Effects on their Immunogenic Potential

1 reference

https://pubmed.ncbi.nlm.nih.gov/27757300

12 December 2020

based on heuristic

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Harnessing PD-L1-specific cytotoxic T cells for anti-leukemia immunotherapy to defeat mechanisms of immune escape mediated by the PD-1 pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/27757300

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based on heuristic

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Spontaneous cytotoxic T-cell responses against survivin-derived MHC class I-restricted T-cell epitopes in situ as well as ex vivo in cancer patients

1 reference

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12 December 2020

based on heuristic

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Identifiers

10.1080/2162402X.2016.1207842

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25 March 2020

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25 March 2020

1 reference

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25 March 2020

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