Triple combination of carbosilane dendrimers, tenofovir and maraviroc as potential microbicide to prevent HIV-1 sexual transmission (Q41339468)

29 September 2017

Triple combination of carbosilane dendrimers, tenofovir and maraviroc as potential microbicide to prevent HIV-1 sexual transmission (English)

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sexually transmitted infection

29 September 2017

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Mª Ángeles Muñoz-Fernández

7

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29 September 2017

Daniel Sepúlveda-Crespo

Daniel Sepúlveda-Crespo

1

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Rafael Gómez

4

Rafael Gómez

1 reference

29 September 2017

6

José Luis Jiménez

1 reference

Francisco Javier De La Mata

29 September 2017

5

Francisco Javier De La Mata

1 reference

Javier Mauricio Sánchez Rodríguez

29 September 2017

2

Javier Sánchez-Rodríguez

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29 September 2017

3

María Jesús Serramía

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29 September 2017

1 January 2015

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29 September 2017

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29 September 2017

10

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29 September 2017

6

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29 September 2017

899-914

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Risk perception of sexually transmitted infections and HIV in Nigerian commercial sex workers living in Barcelona: a study protocol

29 September 2017

1 reference

HIV vaccine development: challenges and opportunities towards solving the HIV vaccine-neutralizing antibody problem

21 January 2018

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Progress and obstacles in the development of an AIDS vaccine

21 January 2018

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HIV due to female sex work: regional and global estimates

21 January 2018

1 reference

How men's power over women fuels the HIV epidemic

21 January 2018

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Was the "ABC" approach (abstinence, being faithful, using condoms) responsible for Uganda's decline in HIV?

21 January 2018

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Sexual pleasure and condom use.

21 January 2018

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Sexual abstinence only programmes to prevent HIV infection in high income countries: systematic review

21 January 2018

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Circumcision in HIV-infected men and its effect on HIV transmission to female partners in Rakai, Uganda: a randomised controlled trial

21 January 2018

1 reference

Development of a comprehensive human immunodeficiency virus type 1 screening algorithm for discovery and preclinical testing of topical microbicides.

21 January 2018

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Development of topical microbicides to prevent the sexual transmission of HIV

21 January 2018

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A lectin isolated from bananas is a potent inhibitor of HIV replication

21 January 2018

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Selective interactions of polyanions with basic surfaces on human immunodeficiency virus type 1 gp120

21 January 2018

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SAVVY® (C31G) Gel for prevention of HIV infection in women: a phase 3, double-blind, randomized, placebo-controlled trial in Ghana

21 January 2018

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Efficacy of Carraguard for prevention of HIV infection in women in South Africa: a randomised, double-blind, placebo-controlled trial

21 January 2018

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Lack of effectiveness of cellulose sulfate gel for the prevention of vaginal HIV transmission

21 January 2018

1 reference

Safety and effectiveness of BufferGel and 0.5% PRO2000 gel for the prevention of HIV infection in women

21 January 2018

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Maraviroc concentrates in the cervicovaginal fluid and vaginal tissue of HIV-negative women

21 January 2018

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Griffithsin, a potent HIV entry inhibitor, is an excellent candidate for anti-HIV microbicide

21 January 2018

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Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5.

21 January 2018

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Cyanovirin-N inhibits AIDS virus infections in vaginal transmission models

21 January 2018

1 reference

A randomized six-day safety study of an antiretroviral microbicide candidate UC781, a non-nucleoside reverse transcriptase inhibitor.

21 January 2018

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The nonnucleoside reverse transcriptase inhibitor MIV-150 in carrageenan gel prevents rectal transmission of simian/human immunodeficiency virus infection in macaques

21 January 2018

1 reference

Pharmacokinetics of 2 dapivirine vaginal microbicide gels and their safety vs. Hydroxyethyl cellulose-based universal placebo gel.

21 January 2018

1 reference

Safety of tenofovir gel, a vaginal microbicide, in South African women: results of the CAPRISA 004 Trial

21 January 2018

1 reference

Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women

21 January 2018

1 reference

Tenofovir-based pre-exposure prophylaxis for HIV prevention

21 January 2018

1 reference

Therapy for HIV: past, present, and future

21 January 2018

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Preclinical evaluation of anti-HIV microbicide products: New models and biomarkers

21 January 2018

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Nanotechnology-based systems for the treatment and prevention of HIV/AIDS.

21 January 2018

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A review of nanotechnological approaches for the prophylaxis of HIV/AIDS.

21 January 2018

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Nanotechnology and the treatment of HIV infection.

21 January 2018

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Emerging nanotechnology approaches for HIV/AIDS treatment and prevention

21 January 2018

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Nano-microbicides: challenges in drug delivery, patient ethics and intellectual property in the war against HIV/AIDS.

21 January 2018

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A randomized controlled trial of the safety of candidate microbicide SPL7013 gel when applied to the penis

21 January 2018

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Safety, tolerability, and pharmacokinetics of SPL7013 gel (VivaGel): a dose ranging, phase I study.

21 January 2018

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SPL7013 Gel (VivaGel®) retains potent HIV-1 and HSV-2 inhibitory activity following vaginal administration in humans

21 January 2018

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Measurement of mucosal biomarkers in a phase 1 trial of intravaginal 3% StarPharma LTD 7013 gel (VivaGel) to assess expanded safety

21 January 2018

1 reference

Behavioural strategies to reduce HIV transmission: how to make them work better

21 January 2018

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Combinatorial prevention of HIV transmission in women: the case for a vaginal microbicide

21 January 2018

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Overview of microbicides for the prevention of human immunodeficiency virus

21 January 2018

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Carbosilane dendrimer nanotechnology outlines of the broad HIV blocker profile.

21 January 2018

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Synergistic activity of carbosilane dendrimers in combination with maraviroc against HIV in vitro.

21 January 2018

1 reference

Antiviral properties against HIV of water soluble copper carbosilane dendrimers and their EPR characterization.

21 January 2018

1 reference

Anionic sulfonated and carboxylated PPI dendrimers with the EDA core: synthesis and characterization of selective metal complexing agents

21 January 2018

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Polyanionic N-donor ligands as chelating agents in transition metal complexes: synthesis, structural characterization and antiviral properties against HIV

21 January 2018

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Synergistic activity profile of carbosilane dendrimer G2-STE16 in combination with other dendrimers and antiretrovirals as topical anti-HIV-1 microbicide

21 January 2018

1 reference

Development of sulphated and naphthylsulphonated carbosilane dendrimers as topical microbicides to prevent HIV-1 sexual transmission.

21 January 2018

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Synthesis, structure and molecular modelling of anionic carbosilane dendrimers.

21 January 2018

1 reference

Reverse transcriptase inhibitors as potential colorectal microbicides

21 January 2018

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Coinfection of hepatic cell lines with human immunodeficiency virus and hepatitis B virus leads to an increase in intracellular hepatitis B surface antigen

21 January 2018

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Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy.

21 January 2018

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The Spanish HIV BioBank: a model of cooperative HIV research

21 January 2018

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Pediatric HIV BioBank: a new role of the Spanish HIV BioBank in pediatric HIV research

21 January 2018

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Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

21 January 2018

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Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies

21 January 2018

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Multiple drug effect analysis with confidence interval

21 January 2018

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Confidence Intervals of Interaction Index for Assessing Multiple Drug Interaction

21 January 2018

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Formulation, pharmacokinetics and pharmacodynamics of topical microbicides

21 January 2018

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Vaginal microbicides and the prevention of HIV transmission

21 January 2018

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L-selectin and P-selectin are novel biomarkers of cervicovaginal inflammation for preclinical mucosal safety assessment of anti-HIV-1 microbicide

21 January 2018

1 reference

Biology of CCR5 and its role in HIV infection and treatment

21 January 2018

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Proteomic analysis of heparin-binding proteins from human seminal plasma: a step towards identification of molecular markers of male fertility

21 January 2018

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Rigorous pre-clinical evaluation of topical microbicides to prevent transmission of human immunodeficiency virus

21 January 2018

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HIV drug-resistant strains as epidemiologic sentinels

21 January 2018

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Combinations of 3-hydroxyphthalic anhydride-modified ovalbumin with antiretroviral drug-based microbicide candidates display synergistic and complementary effects against HIV-1 infection

21 January 2018

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Drug synergy of tenofovir and nanoparticle-based antiretrovirals for HIV prophylaxis

21 January 2018

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Maraviroc versus efavirenz, both in combination with zidovudine-lamivudine, for the treatment of antiretroviral-naive subjects with CCR5-tropic HIV-1 infection

21 January 2018

1 reference

Safety and efficacy of tenofovir/IQP-0528 combination gels - a dual compartment microbicide for HIV-1 prevention

21 January 2018

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Synergistic activity profile of griffithsin in combination with tenofovir, maraviroc and enfuvirtide against HIV-1 clade C.

21 January 2018

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Dendrimers as drugs: discovery and preclinical and clinical development of dendrimer-based microbicides for HIV and STI prevention

21 January 2018

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Candidate polyanion microbicides inhibit HIV-1 infection and dissemination pathways in human cervical explants.

21 January 2018

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Virucidal activity of the dendrimer microbicide SPL7013 against HIV-1.

21 January 2018

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Identification of conserved and variable structures in the human immunodeficiency virus gp120 glycoprotein of importance for CXCR4 binding

21 January 2018

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Maraviroc (UK-427,857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum anti-human immunodeficiency virus type 1 activity

21 January 2018

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In vitro synergistic activity against CCR5-tropic HIV-1 with combinations of potential candidate microbicide molecules HHA, KRV2110 and enfuvirtide (T20).

21 January 2018

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Anti-human immunodeficiency virus interactions of SCH-C (SCH 351125), a CCR5 antagonist, with other antiretroviral agents in vitro

21 January 2018

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Human immunodeficiency virus type 1 entry inhibitors PRO 542 and T-20 are potently synergistic in blocking virus-cell and cell-cell fusion

21 January 2018

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Semen protects CD4+ target cells from HIV infection but promotes the preferential transmission of R5 tropic HIV

21 January 2018

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Selective transmission of R5 HIV-1 variants: where is the gatekeeper?

21 January 2018

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Thiol-ene click chemistry

21 January 2018

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In vitro evaluation of viability, integrity, and inflammation in genital epithelia upon exposure to pharmaceutical excipients and candidate microbicides

21 January 2018

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Application and removal of polyanionic microbicide compounds enhances subsequent infection by HIV-1

21 January 2018

1 reference

Microbicides: a new frontier in HIV prevention

21 January 2018

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Microbicides: topical prevention against HIV

21 January 2018

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Role of seminal plasma in the anti-HIV-1 activity of candidate microbicides

21 January 2018

1 reference

Candidate sulfonated and sulfated topical microbicides: comparison of anti-human immunodeficiency virus activities and mechanisms of action.

21 January 2018

1 reference

Semen-derived amyloid fibrils drastically enhance HIV infection

21 January 2018

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Peptides released by physiological cleavage of semen coagulum proteins form amyloids that enhance HIV infection

21 January 2018

1 reference

Infectious co-factors in HIV-1 transmission herpes simplex virus type-2 and HIV-1: new insights and interventions

21 January 2018

1 reference

21 January 2018

A vaginal fluid simulant

1 reference

21 January 2018

Identifiers

DOI

10.2217/NNM.14.79

1 reference

release_s6lq6qvoxzeljkmj2szgpd6otq

29 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/s6lq6qvoxzeljkmj2szgpd6otq

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference