Concentration-dependent control of pyruvate kinase M mutually exclusive splicing by hnRNP proteins (Q41345033)

29 September 2017

Concentration-dependent control of pyruvate kinase M mutually exclusive splicing by hnRNP proteins (English)

1 reference

29 September 2017

3

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29 September 2017

Mo Chen

1

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PMCID

3698866

29 September 2017

Charles J David

series ordinal

2

1 reference

29 September 2017

5 February 2012

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Nature Structural & Molecular Biology

29 September 2017

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29 September 2017

19

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29 September 2017

3

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29 September 2017

346-354

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https://scigraph.springernature.com/pub.10.1038/nsmb.2219

29 September 2017

0 references

cites work

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Turning on a fuel switch of cancer: hnRNP proteins regulate alternative splicing of pyruvate kinase mRNA.

11 June 2018

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Expression proteomics of UPF1 knockdown in HeLa cells reveals autoregulation of hnRNP A2/B1 mediated by alternative splicing resulting in nonsense-mediated mRNA decay

11 June 2018

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Tumor metabolism: hnRNP proteins get in on the act

11 June 2018

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Pyruvate kinase type M2: a key regulator of the metabolic budget system in tumor cells

11 June 2018

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SF2/ASF autoregulation involves multiple layers of post-transcriptional and translational control

11 June 2018

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The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism

11 June 2018

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Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping

11 June 2018

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HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer

11 June 2018

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hnRNP A2 regulates alternative mRNA splicing of TP53INP2 to control invasive cell migration.

11 June 2018

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Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches

11 June 2018

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Cooperative-binding and splicing-repressive properties of hnRNP A1.

11 June 2018

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11 June 2018

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Dynamic regulation of alternative splicing by silencers that modulate 5' splice site competition

11 June 2018

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CLIP: crosslinking and immunoprecipitation of in vivo RNA targets of RNA-binding proteins

11 June 2018

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Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing

11 June 2018

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Alternative isoform regulation in human tissue transcriptomes

11 June 2018

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Alternative splicing resulting in nonsense-mediated mRNA decay: what is the meaning of nonsense?

11 June 2018

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The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

11 June 2018

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The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing

11 June 2018

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The nonsense-mediated decay RNA surveillance pathway

11 June 2018

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An intronic element contributes to splicing repression in spinal muscular atrophy.

11 June 2018

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CLIP: a method for identifying protein-RNA interaction sites in living cells

11 June 2018

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11 June 2018

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hnRNP A1 controls HIV-1 mRNA splicing through cooperative binding to intron and exon splicing silencers in the context of a conserved secondary structure

11 June 2018

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Distinct sets of adjacent heterogeneous nuclear ribonucleoprotein (hnRNP) A1/A2 binding sites control 5' splice site selection in the hnRNP A1 mRNA precursor

11 June 2018

1 reference

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Listening to silence and understanding nonsense: exonic mutations that affect splicing

11 June 2018

1 reference

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Alternative splicing: multiple control mechanisms and involvement in human disease

11 June 2018

1 reference

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Exon Identity Established through Differential Antagonism between Exonic Splicing Silencer-Bound hnRNP A1 and Enhancer-Bound SR Proteins

11 June 2018

1 reference

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The nonsense-mediated decay pathway and mutually exclusive expression of alternatively spliced FGFR2IIIb and -IIIc mRNAs

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698866

Modulation of exon skipping by high-affinity hnRNP A1-binding sites and by intron elements that repress splice site utilization

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698866

RNA binding specificity of hnRNP A1: significance of hnRNP A1 high-affinity binding sites in pre-mRNA splicing

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698866

Multiple cis-acting sequence elements are required for efficient splicing of simian virus 40 small-t antigen pre-mRNA

11 June 2018

1 reference

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Mammalian heterogeneous nuclear ribonucleoprotein complex protein A1. Large-scale overproduction in Escherichia coli and cooperative binding to single-stranded nucleic acids

11 June 2018

1 reference

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Isolation and characterization of the human pyruvate kinase M gene

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698866

Site-specific modification of pre-mRNA: the 2'-hydroxyl groups at the splice sites

11 June 2018

1 reference

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An RNA map predicting Nova-dependent splicing regulation.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698866

Relative amounts of antagonistic splicing factors, hnRNP A1 and ASF/SF2, change during neoplastic lung growth: implications for pre-mRNA processing

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698866

Altered patterns of expression of members of the heterogeneous nuclear ribonucleoprotein (hnRNP) family in lung cancer.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3698866

A negative element in SMN2 exon 7 inhibits splicing in spinal muscular atrophy

19 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNSMB.2219

hnRNP A1 functions with specificity in repression of SMN2 exon 7 splicing

31 March 2020

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNSMB.2219

hnRNP A1 selectively interacts through its Gly-rich domain with different RNA-binding proteins

31 March 2020

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNSMB.2219

31 March 2020

Identifiers

DOI

10.1038/NSMB.2219

1 reference

release_5yk2x57fdbbjvh3yqg5ffvkywy

29 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/5yk2x57fdbbjvh3yqg5ffvkywy

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMCID

3698866

1 reference

29 September 2017

1 reference

PMCID

3698866