Cotranscriptional spliceosome assembly dynamics and the role of U1 snRNA:5'ss base pairing in yeast (Q41355869)

scientific article published on July 2005

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English	Cotranscriptional spliceosome assembly dynamics and the role of U1 snRNA:5'ss base pairing in yeast	scientific article published on July 2005

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Europe PubMed Central

29 September 2017

Cotranscriptional spliceosome assembly dynamics and the role of U1 snRNA:5'ss base pairing in yeast (English)

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Europe PubMed Central

29 September 2017

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2

Michael Rosbash

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author name string

Scott A Lacadie

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1

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Europe PubMed Central

29 September 2017

1 July 2005

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stated in

Europe PubMed Central

29 September 2017

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Europe PubMed Central

29 September 2017

19

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Europe PubMed Central

29 September 2017

65-75

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Europe PubMed Central

29 September 2017

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Europe PubMed Central

29 September 2017

Branch nucleophile selection in pre-mRNA splicing: evidence for the bulged duplex model

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Four yeast spliceosomal proteins (PRP5, PRP9, PRP11, and PRP21) interact to promote U2 snRNP binding to pre-mRNA

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

The branchpoint residue is recognized during commitment complex formation before being bulged out of the U2 snRNA-pre-mRNA duplex

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

The role of U5 snRNP in pre-mRNA splicing

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Mutations in yeast U5 snRNA alter the specificity of 5' splice-site cleavage

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

The yeast U2A'/U2B complex is required for pre-spliceosome formation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Splicing precedes polyadenylation during Drosophila E74A transcription

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Splicing of Balbiani ring 1 gene pre-mRNA occurs simultaneously with transcription.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Genome-wide bioinformatic and molecular analysis of introns in Saccharomyces cerevisiae

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Nuclear retention of unspliced mRNAs in yeast is mediated by perinuclear Mlp1.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Composition and functional characterization of the yeast spliceosomal penta-snRNP.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

A U1 snRNA:pre-mRNA base pairing interaction is required early in yeast spliceosome assembly but does not uniquely define the 5' cleavage site.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Spliceosomal snRNAs: Mg(2+)-dependent chemistry at the catalytic core?

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

A nuclear cap-binding complex facilitates association of U1 snRNP with the cap-proximal 5' splice site.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

A dual role for BBP/ScSF1 in nuclear pre-mRNA retention and splicing

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Recognition of the TACTAAC box during mRNA splicing in yeast involves base pairing to the U2-like snRNA.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Identification of eight proteins that cross-link to pre-mRNA in the yeast commitment complex

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

The U1 snRNP protein U1C recognizes the 5' splice site in the absence of base pairing

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

RNA splicing and intron turnover are greatly diminished by a mutant yeast branch point

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Interactions of small nuclear RNA's with precursor messenger RNA during in vitro splicing

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Physical isolation of nascent RNA chains transcribed by RNA polymerase II: evidence for cotranscriptional splicing

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

U5 snRNA interacts with exon sequences at 5′ and 3′ splice sites

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

A handful of intron-containing genes produces the lion's share of yeast mRNA.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

A novel base-pairing interaction between U2 and U6 snRNAs suggests a mechanism for the catalytic activation of the spliceosome

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Biochemical analysis of TREX complex recruitment to intronless and intron-containing yeast genes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Involvement of U6 snRNA in 5' splice site selection

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Crystal structure of a model branchpoint-U2 snRNA duplex containing bulged adenosines

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Evidence for a base-pairing interaction between U6 small nuclear RNA and 5' splice site during the splicing reaction in yeast

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Splice site selection, rate of splicing, and alternative splicing on nascent transcripts

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

The yeast splicing factor Mud13p is a commitment complex component and corresponds to CBP20, the small subunit of the nuclear cap-binding complex

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

The splicing factor BBP interacts specifically with the pre-mRNA branchpoint sequence UACUAAC.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Functional recognition of 5' splice site by U4/U6.U5 tri-snRNP defines a novel ATP-dependent step in early spliceosome assembly

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Identification and characterization of yUAP/Sub2p, a yeast homolog of the essential human pre-mRNA splicing factor hUAP56

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Promoter proximal splice sites enhance transcription

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Cross-intron bridging interactions in the yeast commitment complex are conserved in mammals

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Requirements for U2 snRNP addition to yeast pre-mRNA.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Expression of a beta-galactosidase gene containing the ribosomal protein 51 intron is sensitive to the rna2 mutation of yeast

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Interaction of the U1 snRNP with nonconserved intronic sequences affects 5' splice site selection.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Pre-mRNA splicing: awash in a sea of proteins

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Identification and characterization of a yeast homolog of U1 snRNP-specific protein C

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

mRNA splicing efficiency in yeast and the contribution of nonconserved sequences

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Effects of the U1C L13 mutation and temperature regulation of yeast commitment complex formation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Cotranscriptional recruitment of the U1 snRNP to intron-containing genes in yeast

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Early formation of mRNP: license for export or quality control?

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

A biochemical function for the Sm complex.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Mutations in U6 snRNA that alter splice site specificity: implications for the active site

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Identification of functional U1 snRNA-pre-mRNA complexes committed to spliceosome assembly and splicing

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

The yeast MUD2 protein: an interaction with PRP11 defines a bridge between commitment complexes and U2 snRNP addition

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Multiple roles for the yeast SUB2/yUAP56 gene in splicing

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Specific alterations of U1-C protein or U1 small nuclear RNA can eliminate the requirement of Prp28p, an essential DEAD box splicing factor

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Transient interaction of BBP/ScSF1 and Mud2 with the splicing machinery affects the kinetics of spliceosome assembly

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Conservation between yeast and man of a protein associated with U5 small nuclear ribonucleoprotein

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Some cis- and trans-acting mutants for splicing target pre-mRNA to the cytoplasm

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Multiple links between transcription and splicing

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

A quantitative analysis of the effects of 5′ junction and TACTAAC box mutants and mutant combinations on yeast mRNA splicing

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Assembly and disassembly of spliceosomes along a specific pre-messenger RNP fiber.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Cotranscriptional spliceosome assembly occurs in a stepwise fashion and requires the cap binding complex.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Disruption of base pairing between the 5' splice site and the 5' end of U1 snRNA is required for spliceosome assembly

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

On the importance of being co-transcriptional

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

A GAL10-CYC1 hybrid yeast promoter identifies the GAL4 regulatory region as an upstream site

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

An RNA switch at the 5' splice site requires ATP and the DEAD box protein Prp28p

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Site-specific cross-linking of mammalian U5 snRNP to the 5' splice site before the first step of pre-mRNA splicing

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Dynamic association of proteins with the pre-mRNA branch region

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

Intron status and 3'-end formation control cotranscriptional export of mRNA.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

An ATP-independent complex commits pre-mRNA to the mammalian spliceosome assembly pathway

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2005.05.006

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10.1016/J.MOLCEL.2005.05.006

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Europe PubMed Central

29 September 2017

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Europe PubMed Central

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15989965

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29 September 2017

ResearchGate publication ID

7754031

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Cotranscriptional spliceosome assembly dynamics and the role of U1 snRNA:5'ss base pairing in yeast (Q41355869)

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Cotranscriptional spliceosome assembly dynamics and the role of U1 snRNA:5'ss base pairing in yeast (Q41355869)

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