Transient binding patches: a plausible concept for drug binding (Q41373512)

30 September 2017

Transient binding patches: a plausible concept for drug binding (English)

1 reference

30 September 2017

Heino Prinz

1

1 reference

PMCID

2698315

30 September 2017

André Schönichen

series ordinal

2

1 reference

30 September 2017

2 September 2008

1 reference

Journal of Chemical Biology

30 September 2017

1 reference

30 September 2017

1

1 reference

30 September 2017

1-4

1 reference

30 September 2017

95-104

1 reference

https://scigraph.springernature.com/pub.10.1007/s12154-008-0011-5

30 September 2017

0 references

cites work

Structure-Based Dissection of the Natural Product Cyclopentapeptide Chitinase Inhibitor Argifin

1 reference

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High-throughput screening assays for the identification of chemical probes

1 October 2017

1 reference

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On the reaction of cells and of nerve-endings to certain poisons, chiefly as regards the reaction of striated muscle to nicotine and to curari

1 October 2017

1 reference

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Discovery of protein phosphatase inhibitor classes by biology-oriented synthesis

1 October 2017

1 reference

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High-throughput assays for promiscuous inhibitors.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698315

Discovery of Mycobacterium tuberculosis protein tyrosine phosphatase A (MptpA) inhibitors based on natural products and a fragment-based approach

1 October 2017

1 reference

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ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

1 October 2017

1 reference

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Mechanistic considerations in high-throughput screening

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698315

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698315

Drug discovery: a historical perspective

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698315

The Hill equation revisited: uses and misuses.

1 October 2017

1 reference

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Calcium currents in the A7r5 smooth muscle-derived cell line. An allosteric model for calcium channel activation and dihydropyridine agonist action

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698315

Ligand-induced accelerated dissociation of (+)-cis-diltiazem from L-type Ca2+ channels is simply explained by competition for individual attachment points

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698315

Local anesthetics differentiate dihydropyridine calcium antagonist binding sites in rat brain and cardiac membranes.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698315

Ligand binding to the membrane-bound acetylcholine receptor from Torpedo marmorata: a complete mathematical analysis

11 June 2018

1 reference

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How to identify a pharmacophore

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698315

Methods for analyzing cooperativity in phosphoglycerate dehydrogenase

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698315

An exact mathematical expression for describing competitive binding of two different ligands to a protein molecule.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698315

Positive heterotropic allosteric regulators of dihydropyridine binding increase the Ca2+ affinity of the L-type Ca2+ channel. Stereoselective reversal by the novel Ca2+ antagonist BM 20.1140.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698315

Complex molecular mechanism for dihydropyridine binding to L-type Ca(2+)-channels as revealed by fluorescence resonance energy transfer

19 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19568802

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S12154-008-0011-5

1 reference

30 September 2017

1 reference

30 September 2017

1 reference

PMCID

2698315