Drug interactions with proton pump inhibitors (Q41428950)

30 September 2017

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title

Drug interactions with proton pump inhibitors (English)

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30 September 2017

P Unge

1

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PubMed ID

9098655

30 September 2017

T Andersson

series ordinal

2

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30 September 2017

1 March 1997

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30 September 2017

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30 September 2017

16

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30 September 2017

171-179

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30 September 2017

3

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https://scigraph.springernature.com/pub.10.2165/00002018-199716030-00003

30 September 2017

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cites work

Nature of cytochromes P450 involved in the 2-/4-hydroxylations of estradiol in human liver microsomes

1 reference

12 December 2020

Genetically determined variability in acetylation and oxidation. Therapeutic implications

1 reference

12 December 2020

Correlation of human cytochrome P4502C substrate specificities with primary structure: warfarin as a probe

1 reference

12 December 2020

Cytochrome P450: evolution and functional diversity.

1 reference

12 December 2020

Increase of cytochrome P450IA2 activity by omeprazole: evidence by the 13C-[N-3-methyl]-caffeine breath test in poor and extensive metabolizers of S-mephenytoin

1 reference

12 December 2020

Effects of ranitidine and sucralfate on ketoconazole bioavailability

1 reference

12 December 2020

Oxidative metabolism of omeprazole in human liver microsomes: cosegregation with S-mephenytoin 4'-hydroxylation

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12 December 2020

Identification of human liver cytochrome P450 isoforms mediating omeprazole metabolism

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12 December 2020

Diazepam metabolism by human liver microsomes is mediated by both S-mephenytoin hydroxylase and CYP3A isoforms

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12 December 2020

Pharmacokinetics, metabolism and interactions of acid pump inhibitors. Focus on omeprazole, lansoprazole and pantoprazole

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12 December 2020

Relation between chloroguanide bioactivation to cycloguanil and the genetically determined metabolism of mephenytoin in humans

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12 December 2020

Biotransformation of caffeine by microsomes from human liver. Kinetics and inhibition studies

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12 December 2020

Lack of effect of antacids on plasma concentrations of omeprazole given as enteric-coated granules

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12 December 2020

No influence of single intravenous doses of omeprazole on theophylline elimination kinetics

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12 December 2020

Omeprazole treatment does not affect the metabolism of caffeine

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12 December 2020

Review article: the continuing development of proton pump inhibitors with particular reference to pantoprazole

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12 December 2020

In vitro proguanil activation to cycloguanil by human liver microsomes is mediated by CYP3A isoforms as well as by S-mephenytoin hydroxylase

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12 December 2020

Identification of human liver cytochrome P450 isoforms mediating secondary omeprazole metabolism

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12 December 2020

The effect of oral omeprazole on the disposition of lignocaine.

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12 December 2020

Slow omeprazole metabolizers are also poor S-mephenytoin hydroxylators.

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12 December 2020

Identification of an inducible form of cytochrome P-450 in human liver

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12 December 2020

Characterization of human cytochromes P450 involved in theophylline 8-hydroxylation

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12 December 2020

Development of an oral formulation of omeprazole.

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12 December 2020

Pharmacokinetics--a relevant factor for the choice of a drug?

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12 December 2020

Molecular basis of genetic variation in debrisoquin hydroxylation in Chinese subjects: polymorphism in RFLP and DNA sequence of CYP2D6

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12 December 2020

Importance of genetic factors in the regulation of diazepam metabolism: relationship to S-mephenytoin, but not debrisoquin, hydroxylation phenotype.

1 reference

12 December 2020

Minor effect of multiple dose omeprazole on the pharmacokinetics of digoxin after a single oral dose

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12 December 2020

Enhanced phenacetin metabolism in human subjects fed charcoal-broiled beef

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12 December 2020

Characterisation of theophylline metabolism by human liver microsomes. Inhibition and immunochemical studies

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12 December 2020

Effect of cigarette smoking on phenacetin metabolism

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12 December 2020

Evidence that CYP2C19 is the major (S)-mephenytoin 4'-hydroxylase in humans

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12 December 2020

Stimulatory effect of brussels sprouts and cabbage on human drug metabolism

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12 December 2020

Influence of single- and multiple-dose omeprazole treatment on nifedipine pharmacokinetics and effects in healthy subjects

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12 December 2020

Lack of effect of omeprazole treatment on steady-state plasma levels of metoprolol

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12 December 2020

Lansoprazole does not affect the bioavailability of oral contraceptives

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12 December 2020

Effect of omeprazole treatment on diazepam plasma levels in slow versus normal rapid metabolizers of omeprazole.

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12 December 2020

Oral phenytoin pharmacokinetics during omeprazole therapy

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12 December 2020

Lack of effect of pantoprazole on the pharmacodynamics and pharmacokinetics of warfarin

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12 December 2020

Human P450PCN1: sequence, chromosome localization, and direct evidence through cDNA expression that P450PCN1 is nifedipine oxidase

1 reference

12 December 2020

Hepatic microsomal tolbutamide hydroxylation in Japanese: in vitro evidence for rapid and slow metabolizers

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12 December 2020

Continuing development of acid pump inhibitors: site of action of pantoprazole.

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12 December 2020

Omeprazole therapy does not affect pharmacokinetics of orally administered ethanol in healthy male subjects

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12 December 2020

Relationships between the levels of cytochrome P4502C9 and its prototypic catalytic activities in human liver microsomes

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12 December 2020

Influence of lansoprazole treatment on diazepam plasma concentrations

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12 December 2020

Propranolol's metabolism is determined by both mephenytoin and debrisoquin hydroxylase activities

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12 December 2020

Human liver carbamazepine metabolism. Role of CYP3A4 and CYP2C8 in 10,11-epoxide formation

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12 December 2020

Relationship between phenytoin and tolbutamide hydroxylations in human liver microsomes

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12 December 2020

Polymorphic hydroxylation of S-mephenytoin and omeprazole metabolism in Caucasian and Chinese subjects

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12 December 2020

A study of the interaction between omeprazole and phenytoin in epileptic patients

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12 December 2020

A study of the interaction between omeprazole and cyclosporine in renal transplant patients

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12 December 2020

Lack of effect of omeprazole, cimetidine, and ranitidine on the pharmacokinetics of ethanol in fasting male volunteers.

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12 December 2020

Lack of influence of pantoprazole on the disposition kinetics of theophylline in man.

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12 December 2020

A dose-effect study of the in vivo inhibitory effect of quinidine on sparteine oxidation in man.

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12 December 2020

Omeprazole does not affect measured CYP3A4 activity using the erythromycin breath test

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12 December 2020

Drugs other than H2-receptor antagonists as clinically important inhibitors of drug metabolism in vivo

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12 December 2020

Effect of omeprazole--a gastric proton pump inhibitor--on pentagastrin stimulated acid secretion in man

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12 December 2020

Differences in the cytochrome P-450 isoenzymes involved in the 2-hydroxylation of oestradiol and 17 alpha-ethinyloestradiol. Relative activities of rat and human liver enzymes

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12 December 2020

Disposition kinetics and metabolism of omeprazole in extensive and poor metabolizers of S-mephenytoin 4'-hydroxylation recruited from an Oriental population.

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12 December 2020

Effect of omeprazole on concentrations of clarithromycin in plasma and gastric tissue at steady state

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12 December 2020

The interaction of proton pump inhibitors with cytochromes P450.

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12 December 2020

Omeprazole does not enhance the metabolism of phenacetin, a marker of CYP1A2 activity, in healthy volunteers

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12 December 2020

Lidocaine metabolism in human liver microsomes by cytochrome P450IIIA4.

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12 December 2020

Propranolol steady-state pharmacokinetics are unaltered by omeprazole

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12 December 2020

Oxidation of quinidine by human liver cytochrome P-450

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12 December 2020

The mechanism of action of the gastric acid secretion inhibitor omeprazole

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12 December 2020

Theophylline steady state pharmacokinetics is not altered by omeprazole

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12 December 2020

Effects of omeprazole on ethanol metabolism: an in vitro and in vivo rat and human study

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12 December 2020

A form of cytochrome P450 in man, orthologous to form d in the rat, catalyses the O-deethylation of phenacetin and is inducible by cigarette smoking

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12 December 2020

Twenty-four-hour intragastric acidity and plasma gastrin concentration before and during treatment with either ranitidine or omeprazole

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12 December 2020

A study of the interaction of omeprazole and warfarin in anticoagulated patients

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12 December 2020

Stereoselective interaction of omeprazole with warfarin in healthy men

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12 December 2020

Effect of omeprazole and cimetidine on plasma diazepam levels.

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12 December 2020

Defective metabolism of metoprolol in poor hydroxylators of debrisoquine

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12 December 2020

Substituted benzimidazoles inhibit gastric acid secretion by blocking (H+ + K+) ATPase

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12 December 2020

Influence of gastric acidity on the bioavailability of digoxin

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12 December 2020

Tolbutamide and mephenytoin hydroxylation by human cytochrome P450s in the CYP2C subfamily

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12 December 2020

Absence of an inhibitory effect of omeprazole and nizatidine on phenytoin disposition, a marker of CYP2C activity

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12 December 2020

No influence of pantoprazole on the pharmacokinetics of phenytoin

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12 December 2020

Cyclosporine metabolism in human liver: identification of a cytochrome P-450III gene family as the major cyclosporine-metabolizing enzyme explains interactions of cyclosporine with other drugs.

1 reference

12 December 2020

Characterization of human liver cytochromes P-450 involved in theophylline metabolism

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12 December 2020

No effect of omeprazole-induced hypoacidity on the bioavailability of amoxycillin or bacampicillin

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12 December 2020

Omeprazole fails to alter the cytochrome P450-dependent 2-hydroxylation of estradiol in male volunteers

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12 December 2020

Effect of omeprazole on gastric first-pass metabolism of ethanol

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12 December 2020

The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans

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12 December 2020

Omeprazole inhibits oxidative drug metabolism. Studies with diazepam and phenytoin in vivo and 7-ethoxycoumarin in vitro.

1 reference

12 December 2020

Interethnic differences in omeprazole metabolism in the two S-mephenytoin hydroxylation phenotypes studied in Caucasians and Orientals

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12 December 2020

Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects

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12 December 2020

Quinidine single dose pharmacokinetics and pharmacodynamics are unaltered by omeprazole

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12 December 2020

Specific and dose-dependent enzyme induction by omeprazole in human beings.

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12 December 2020

Co-regulation of phenytoin and tolbutamide metabolism in humans

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12 December 2020

The effect of food and antacids on lansoprazole absorption and disposition

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12 December 2020

10.2165/00002018-199716030-00003

Identifiers

DOI

1 reference

PubMed ID

9098655

Dimensions Publication ID

30 September 2017

0 references

1 reference

PubMed ID

9098655