Two TRPV1 receptor antagonists are effective in two different experimental models of migraine (Q41440081)

30 September 2017

Two TRPV1 receptor antagonists are effective in two different experimental models of migraine (English)

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30 September 2017

1 reference

5

Sigrid Schuh-Hofer

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author name string

Jannis E Meents

1

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30 September 2017

Jan Hoffmann

2

1 reference

30 September 2017

Sandra R Chaplan

3

1 reference

30 September 2017

Lars Neeb

4

1 reference

30 September 2017

Sigrid Schuh-Hofer

5

1 reference

30 September 2017

Alan Wickenden

6

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30 September 2017

Uwe Reuter

7

1 reference

30 September 2017

24 June 2015

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The journal of headache and pain : official journal of the Italian Society for the Study of Headaches

30 September 2017

1 reference

30 September 2017

16

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30 September 2017

57

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Creative Commons Attribution 4.0 International

30 September 2017

start time

24 June 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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Pharmacological blockade of the vanilloid receptor TRPV1 elicits marked hyperthermia in humans

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The vanilloid receptor TRPV1 is tonically activated in vivo and involved in body temperature regulation

1 October 2017

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Characterization of SB-705498, a potent and selective vanilloid receptor-1 (VR1/TRPV1) antagonist that inhibits the capsaicin-, acid-, and heat-mediated activation of the receptor

1 October 2017

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Identification and biological evaluation of 4-(3-trifluoromethylpyridin-2-yl)piperazine-1-carboxylic acid (5-trifluoromethylpyridin-2-yl)amide, a high affinity TRPV1 (VR1) vanilloid receptor antagonist

1 October 2017

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Defeating migraine pain with triptans: a race against the development of cutaneous allodynia.

1 October 2017

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Capsaicin-sensitive neurogenic sensory vasodilatation in the dura mater of the rat.

1 October 2017

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CGRP may play a causative role in migraine

1 October 2017

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Oral triptans (serotonin 5-HT(1B/1D) agonists) in acute migraine treatment: a meta-analysis of 53 trials

1 October 2017

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Sensory nerves in man and their role in primary headaches

1 October 2017

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Neurogenic inflammation in the context of migraine

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Distribution of mRNA for vanilloid receptor subtype 1 (VR1), and VR1-like immunoreactivity, in the central nervous system of the rat and human

1 October 2017

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1 October 2017

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Vasoactive peptide release in the extracerebral circulation of humans during migraine headache

1 October 2017

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TRPV1 receptor blockade is ineffective in different in vivo models of migraine

1 October 2017

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Distribution of fos-like immunoreactivity in the medullary and upper cervical dorsal horn produced by stimulation of dural blood vessels in the rat.

11 June 2018

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Safety, Tolerability and Pharmacokinetic and Pharmacodynamic Learnings from a Double-Blind, Randomized, Placebo-Controlled, Sequential Group First-in-Human Study of the TRPV1 Antagonist, JNJ-38893777, in Healthy Men.

11 June 2018

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19 August 2018

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Olvanil acts on transient receptor potential vanilloid channel 1 and cannabinoid receptors to modulate neuronal transmission in the trigeminovascular system

19 August 2018

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Primary trigeminal afferents are the main source for stimulus-induced CGRP release into jugular vein blood and CSF.

19 August 2018

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SNP variants within the vanilloid TRPV1 and TRPV3 receptor genes are associated with migraine in the Spanish population.

19 August 2018

1 reference

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Electrophysiological and morphological properties of neurons in the substantia gelatinosa of the mouse trigeminal subnucleus caudalis

19 August 2018

1 reference

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The effects of the TRPV1 receptor antagonist SB-705498 on trigeminovascular sensitisation and neurotransmission

19 August 2018

1 reference

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Intracisternal injection of inflammatory soup activates the trigeminal nerve system.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491068

Serotonin depletion increases nociception-evoked trigeminal NMDA receptor phosphorylation

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491068

Early vs. non-early intervention in acute migraine-'Act when Mild (AwM)'. A double-blind, placebo-controlled trial of almotriptan

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491068

Ethanol causes neurogenic vasodilation by TRPV1 activation and CGRP release in the trigeminovascular system of the guinea pig.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491068

Pharmacology and antitussive efficacy of 4-(3-trifluoromethyl-pyridin-2-yl)-piperazine-1-carboxylic acid (5-trifluoromethyl-pyridin-2-yl)-amide (JNJ17203212), a transient receptor potential vanilloid 1 antagonist in guinea pigs.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491068

CGRP release and c-fos expression within trigeminal nucleus caudalis of the rat following glyceryltrinitrate infusion.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491068

Expression of vanilloid receptor TRPV1 in the rat trigeminal sensory nuclei

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491068

Anandamide acts as a vasodilator of dural blood vessels in vivo by activating TRPV1 receptors

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491068

[3H]Resiniferatoxin autoradiography in the CNS of wild-type and TRPV1 null mice defines TRPV1 (VR-1) protein distribution

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491068

Vanilloid type 1 receptors (VR1) on trigeminal sensory nerve fibres play a minor role in neurogenic dural vasodilatation, and are involved in capsaicin-induced dural dilation

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491068

Release of calcitonin gene-related peptide (CGRP) from guinea pig dura mater in vitro is inhibited by sumatriptan but unaffected by nitric oxide

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491068

The NMDA receptor antagonist MK-801 reduces capsaicin-induced c-fos expression within rat trigeminal nucleus caudalis

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491068

Chemical stimulation of the intracranial dura induces enhanced responses to facial stimulation in brain stem trigeminal neurons

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491068

[Animal models and their results in relation to the therapy of migraine]

19 August 2018

1 reference

12 December 2020

Receptor systems mediating c-fos expression within trigeminal nucleus caudalis in animal models of migraine

1 reference

12 December 2020

Neurobiology of migraine

1 reference

12 December 2020

A dominant role of acid pH in inflammatory excitation and sensitization of nociceptors in rat skin, in vitro

1 reference

12 December 2020

Symptoms of cutaneous sensitivity pre-treatment and post-treatment: results from the rizatriptan TAME studies

1 reference

12 December 2020

Stimulation of the superior sagittal sinus in the cat causes release of vasoactive peptides

1 reference

12 December 2020

10.1186/S10194-015-0539-Z

Identifiers

DOI

1 reference

Dimensions Publication ID

30 September 2017

0 references

1 reference

30 September 2017

PubMed publication ID

26109436

1 reference