Suramin derivatives as inhibitors and activators of protein-tyrosine phosphatases (Q41464016)

1 October 2017

Suramin derivatives as inhibitors and activators of protein-tyrosine phosphatases (English)

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1 October 2017

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Daniel F McCain

1

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1 October 2017

Li Wu

2

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1 October 2017

Peter Nickel

3

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1 October 2017

Matthias U Kassack

4

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1 October 2017

Annett Kreimeyer

5

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1 October 2017

Antonio Gagliardi

6

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1 October 2017

Delwood C Collins

7

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1 October 2017

Zhong-Yin Zhang

8

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1 October 2017

language of work or name

English

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publication date

20 January 2004

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Journal of Biological Chemistry

1 October 2017

13

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based on heuristic

inferred from page(s)

published in

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1 October 2017

279

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1 October 2017

15

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1 October 2017

14713-14725

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Suramin is an active site-directed, reversible, and tight-binding inhibitor of protein-tyrosine phosphatases

1 October 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Suramin rapidly alters cellular tyrosine phosphorylation in prostate cancer cell lines

21 January 2018

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Suramin, an experimental chemotherapeutic drug, activates the receptor for epidermal growth factor and promotes growth of certain malignant cells

21 January 2018

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Protein tyrosine phosphatases: prospects for therapeutics

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M312488200

Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Tyrosine phosphate hydrolysis of host proteins by an essential Yersinia virulence determinant

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

New insights into the transmembrane protein tyrosine phosphatase CD45.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

The cell cycle Cdc25A tyrosine phosphatase is activated in degenerating postmitotic neurons in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Constitutive Cdc25B tyrosine phosphatase activity in adult brain neurons with M phase-type alterations in Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M312488200

Acquisition of a specific and potent PTP1B inhibitor from a novel combinatorial library and screening procedure

21 January 2018

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Aurintricarboxylic acid blocks in vitro and in vivo activity of YopH, an essential virulent factor of Yersinia pestis, the agent of plague.

21 January 2018

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Coscinosulfate, a CDC25 phosphatase inhibitor from the sponge Coscinoderma mathewsi

21 January 2018

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Syntheses and biological activities of a novel group of steroidal derived inhibitors for human Cdc25A protein phosphatase

21 January 2018

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Discovery and biological evaluation of a new family of potent inhibitors of the dual specificity protein phosphatase Cdc25.

21 January 2018

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Synthesis of a tetronic acid library focused on inhibitors of tyrosine and dual-specificity protein phosphatases and its evaluation regarding VHR and cdc25B inhibition

21 January 2018

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The solid phase synthesis of tetrahydroisoquinolines having cdc25B inhibitory activity

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M312488200

Generation of an Ugi library of phosphate mimic-containing compounds and identification of novel dual specific phosphatase inhibitors

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M312488200

Intra- and intermolecular interactions between intracellular domains of receptor protein-tyrosine phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Characterization of recombinant CD45 cytoplasmic domain proteins. Evidence for intramolecular and intermolecular interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Suramin analogues with a 2-phenylbenzimidazole moiety as partial structure; potential anti HIV- and angiostatic drugs, 2: Sulfanilic acid-, benzenedisulfonic acid-, and naphthalenetrisulfonic acid analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Stability of suramin in aqueous solution; possible implications for the search for suramin metabolites in patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: a paradigm for inhibitor design

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

The catalytic mechanism of Cdc25A phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Crystal structure of the catalytic domain of the human cell cycle control phosphatase, Cdc25A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Restoration of potent protein-tyrosine phosphatase activity into the membrane-distal domain of receptor protein-tyrosine phosphatase alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

21 January 2018

Cdc2 regulatory factors

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https://api.crossref.org/works/10.1074%2FJBC.M312488200

CDC25 phosphatases as potential human oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Role of the Cdc25A phosphatase in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Clinical significance of CDC25A and CDC25B expression in squamous cell carcinomas of the oesophagus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Expression of cdc25A and cdc25B proteins in thyroid neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Dual G1 and G2/M phase inhibition by SC-alpha alpha delta 9, a combinatorially derived Cdc25 phosphatase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Effect of suramin on p34cdc2 kinase in vitro and in extracts from human H69 cells: evidence for a double mechanism of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

The looming threat of bioterrorism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Plague as a biological weapon: medical and public health management. Working Group on Civilian Biodefense

21 January 2018

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Genomics and future biological weapons: the need for preventive action by the biomedical community

21 January 2018

1 reference

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Identification of p130Cas as a substrate of Yersinia YopH (Yop51), a bacterial protein tyrosine phosphatase that translocates into mammalian cells and targets focal adhesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

The PTPase YopH inhibits uptake of Yersinia, tyrosine phosphorylation of p130Cas and FAK, and the associated accumulation of these proteins in peripheral focal adhesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

The Yersinia tyrosine phosphatase: specificity of a bacterial virulence determinant for phosphoproteins in the J774A.1 macrophage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Crystal structure of the tandem phosphatase domains of RPTP LAR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Structural basis for inhibition of receptor protein-tyrosine phosphatase-alpha by dimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

The structure of the membrane distal phosphatase domain of RPTPalpha reveals interdomain flexibility and an SH2 domain interaction region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Regulation of receptor protein-tyrosine phosphatase alpha by oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Mitotic activation of protein-tyrosine phosphatase alpha and regulation of its Src-mediated transforming activity by its sites of protein kinase C phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

The guanine nucleotide exchange factor trio mediates axonal development in the Drosophila embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Multiple interactions between receptor protein-tyrosine phosphatase (RPTP) alpha and membrane-distal protein-tyrosine phosphatase domains of various RPTPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

The second catalytic domain of protein tyrosine phosphatase delta (PTP delta) binds to and inhibits the first catalytic domain of PTP sigma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Dimerization in vivo and inhibition of the nonreceptor form of protein tyrosine phosphatase epsilon

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Ligand-mediated negative regulation of a chimeric transmembrane receptor tyrosine phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Dimerization inhibits the activity of receptor-like protein-tyrosine phosphatase-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Receptor-like protein tyrosine phosphatase alpha homodimerizes on the cell surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Dimerization-induced inhibition of receptor protein tyrosine phosphatase function through an inhibitory wedge

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Negative regulation of CD45 by differential homodimerization of the alternatively spliced isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Dimerization of receptor protein-tyrosine phosphatase alpha in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

The mechanism of dephosphorylation of extracellular signal-regulated kinase 2 by mitogen-activated protein kinase phosphatase 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Specificity of natural and artificial substrates for human Cdc25A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Two mechanisms activate PTPalpha during mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Protein kinase C delta induces Src kinase activity via activation of the protein tyrosine phosphatase PTP alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Dysidiolide and related gamma-hydroxy butenolide compounds as inhibitors of the protein tyrosine phosphatase, CDC25

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Naphthoquinone analogs as inactivators of cdc25 phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Dysidiolide: A Novel Protein Phosphatase Inhibitor from the Caribbean SpongeDysidea etheriade Laubenfels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Rapid, highly sensitive gradient narrow-bore high-performance liquid chromatographic determination of suramin and its analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Transition state and rate-limiting step of the reaction catalyzed by the human dual-specificity phosphatase, VHR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Antiangiogenic and antiproliferative activity of suramin analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

cdc25a and the splicing variant cdc25b2, but not cdc25B1, -B3 or -C, are over-expressed in aggressive human non-Hodgkin's lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Differential expression of cdc25 cell-cycle-activating phosphatases in human colorectal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Expression of the cdc25B gene as a prognosis marker in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Synthesis of the novel analogues of dysidiolide and their structure-activity relationship

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Vitamin K3 induces cell cycle arrest and cell death by inhibiting Cdc25 phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Potent and highly selective inhibitors of the protein tyrosine phosphatase 1B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Comparative kinetic analysis and substrate specificity of the tandem catalytic domains of the receptor-like protein-tyrosine phosphatase alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

Stable interdomain interaction within the cytoplasmic domain of CD45 increases enzyme stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312488200

21 January 2018

Identifiers

DOI

10.1074/JBC.M312488200

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1 October 2017

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