The TCF-1 and LEF-1 transcription factors have cooperative and opposing roles in T cell development and malignancy. (Q41510704)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23103132%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

The TCF-1 and LEF-1 transcription factors have cooperative and opposing roles in T cell development and malignancy (English)

1 reference

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16 February 2020

10

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16 February 2020

David Meyerholz

9

1 reference

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16 February 2020

Charles M Knudson

11

1 reference

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16 February 2020

Hai-Hui Xue

13

1 reference

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16 February 2020

author name string

Shuyang Yu

1

1 reference

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16 February 2020

Xinyuan Zhou

2

1 reference

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16 February 2020

Farrah C Steinke

3

1 reference

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16 February 2020

Chengyu Liu

4

1 reference

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16 February 2020

Shann-Ching Chen

5

1 reference

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16 February 2020

Oksana Zagorodna

6

1 reference

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16 February 2020

Xuefang Jing

7

1 reference

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16 February 2020

Yoshifumi Yokota

8

1 reference

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16 February 2020

Dong-Mei Zhao

12

1 reference

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16 February 2020

language of work or name

English

0 references

publication date

25 October 2012

1 reference

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16 February 2020

1 reference

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16 February 2020

volume

37

1 reference

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16 February 2020

page(s)

813-826

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16 February 2020

issue

5

1 reference

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Regulation of mature T cell responses by the Wnt signaling pathway

16 February 2020

cites work

1 reference

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T-cell factor 1 is a gatekeeper for T-cell specification in response to Notch signaling.

10 June 2018

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Oncogenic and tumor suppressor functions of Notch in cancer: it's NOTCH what you think.

10 June 2018

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A critical role for TCF-1 in T-lineage specification and differentiation

10 June 2018

1 reference

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Differentiation and persistence of memory CD8(+) T cells depend on T cell factor 1

10 June 2018

1 reference

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Notch regulation of early thymocyte development

10 June 2018

1 reference

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LEF-1 is a prosurvival factor in chronic lymphocytic leukemia and is expressed in the preleukemic state of monoclonal B-cell lymphocytosis

10 June 2018

1 reference

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Inactivation of LEF1 in T-cell acute lymphoblastic leukemia

10 June 2018

1 reference

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Beta-catenin hits chromatin: regulation of Wnt target gene activation

10 June 2018

1 reference

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E and ID proteins branch out.

10 June 2018

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Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia

10 June 2018

1 reference

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Transcription factor expression dynamics of early T-lymphocyte specification and commitment

10 June 2018

1 reference

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Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras-initiated leukemia

10 June 2018

1 reference

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The canonical Wnt signaling pathway plays an important role in lymphopoiesis and hematopoiesis

10 June 2018

1 reference

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Molecular pathogenesis of T-cell leukaemia and lymphoma

10 June 2018

1 reference

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A novel role for Lef-1, a central transcription mediator of Wnt signaling, in leukemogenesis

10 June 2018

1 reference

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Launching the T-cell-lineage developmental programme

10 June 2018

1 reference

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Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

10 June 2018

1 reference

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Beta-catenin stabilization stalls the transition from double-positive to single-positive stage and predisposes thymocytes to malignant transformation

10 June 2018

1 reference

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Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia

10 June 2018

1 reference

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From stem cell to T cell: one route or many?

10 June 2018

1 reference

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Notch1 mutations are important for leukemic transformation in murine models of precursor-T leukemia/lymphoma

10 June 2018

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Activating Notch1 mutations in mouse models of T-ALL.

10 June 2018

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The RUNX genes: gain or loss of function in cancer

10 June 2018

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Wnt signalling in stem cells and cancer

10 June 2018

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Molecular genetics of T cell development

10 June 2018

1 reference

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Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

10 June 2018

1 reference

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10 June 2018

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Separation of Notch1 promoted lineage commitment and expansion/transformation in developing T cells

10 June 2018

1 reference

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Constitutive Bcl-2 expression throughout the hematopoietic compartment affects multiple lineages and enhances progenitor cell survival

10 June 2018

1 reference

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Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1.

10 June 2018

1 reference

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Overexpression of the Helix-Loop-Helix protein Id2 blocks T cell development at multiple stages.

10 June 2018

1 reference

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Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

10 June 2018

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Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2.

10 June 2018

1 reference

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Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1

10 June 2018

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High incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout mice

10 June 2018

1 reference

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E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas

10 June 2018

1 reference

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Overexpression of LEF1 predicts unfavorable outcome in adult patients with B-precursor acute lymphoblastic leukemia.

10 June 2018

1 reference

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A Wnt-fall for gene regulation: repression

19 August 2018

1 reference

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Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1.

19 August 2018

1 reference

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Cooperating pre-T-cell receptor and TCF-1-dependent signals ensure thymocyte survival.

19 August 2018

1 reference

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Mastermind critically regulates Notch-mediated lymphoid cell fate decisions.

19 August 2018

1 reference

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Beta-catenin-sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer

19 August 2018

1 reference

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Notch1 co-opts lymphoid enhancer factor 1 for survival of murine T-cell lymphomas

19 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23103132

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

An HMG-box-containing T-cell factor required for thymocyte differentiation.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23103132

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Critical involvement of Tcf-1 in expansion of thymocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23103132

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.IMMUNI.2012.08.009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23103132%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23103132%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23103132%20AND%20SRC:MED&resulttype=core&format=json