clavulanic acid ingelesa (Q415709)

Wikidatatik
Nabigaziora joan Bilaketara joan
konposatu kimiko
aldatu
Hizkuntza Etiketa Deskribapena Goitizenak
euskara
Ez da etiketarik zehaztu
konposatu kimiko
    ingelesa
    clavulanic acid
    Β-lactam molecule used as β-lactamase inhibitor to overcome antibiotic resistance in bacteria
    • (2R,3Z,5R)-3-(2-HYDROXYETHYLIDENE)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
    • (Z)-(2R,5R)-3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo(3.2.0)heptane-2-carboxylic acid
    • Clavulanic Acid
    • Clavulansaeure
    • Acidum clavulanicum
    • Acide clavulanique
    • MM 14151
    • Acido clavulanico
    • Antibiotic mm 14151
    • BRL-14151
    • ácido clavulánico
    • Clavulansäure
    • clavulonic acid
    • Clavulanate
    • acide clavulanique
    • Antibiotic MM 14151
    • Clavulanic acid

    Adierazpenak

    honako hau da
    type of chemical entity ingelesa
    0 erreferentzia
    honen azpiklasea
    Alkaloide
    0 erreferentzia
    erabilera
    farmako
    Erreferentzia bat
    izenburua
    Clavulanate (ingelesa)
    non adierazia
    DrugBank ingelesa
    lanaren edo izenaren hizkuntza
    ingeles
    argitaratze-data
    17 azaroa 2015
    DrugBank ID ingelesa
    00766
    egitura kimikoa
    Clavulanic acid.svg
    512 × 360; 5 KB
    0 erreferentzia
    masa
    199,048 masa atomikoaren unitate
    Erreferentzia bat
    non adierazia
    PubChem
    PubChem-en identifikatzailea
    5280980
    lanaren edo izenaren hizkuntza
    ingeles
    izenburua
    CLAVULANIC ACID (ingelesa)
    sartze-data
    19 urria 2016
    SMILES
    C1C2N(C1=O)C(C(=CCO)O2)C(=O)O
    Erreferentzia bat
    non adierazia
    PubChem
    PubChem-en identifikatzailea
    5280980
    lanaren edo izenaren hizkuntza
    ingeles
    izenburua
    CLAVULANIC ACID (ingelesa)
    sartze-data
    19 azaroa 2016
    isomeric SMILES ingelesa
    C1[C@@H]2N(C1=O)[C@H](/C(=C/CO)/O2)C(=O)O
    Erreferentzia bat
    non adierazia
    PubChem
    PubChem-en identifikatzailea
    5280980
    lanaren edo izenaren hizkuntza
    ingeles
    izenburua
    CLAVULANIC ACID (ingelesa)
    sartze-data
    19 azaroa 2016
    taxon honetan dago
    Streptomyces clavuligerus
    69 erreferentzia
    non adierazia
    The origin of the β-lactam carbons of clavulanic acid ingelesa
    non adierazia
    Evidence that arginine is a later metabolic intermediate than ornithine in the biosynthesis of clavulanic acid by Streptomyces clavuligerus ingelesa
    non adierazia
    Evidence that the immediate biosynthetic precursor of clavulanic acid is its N-aldehyde analogue ingelesa
    non adierazia
    Biosynthesis of clavulanic acid: origin of the C3 unit ingelesa
    non adierazia
    Biosynthesis of clavulanic acid: origin of the C5 unit ingelesa
    non adierazia
    The stereochemical fate of (2RS,5R)- and (2RS,5S)-[5-3H]ornithine in clavulanic acid biosynthesis ingelesa
    non adierazia
    Clavulanic acid biosynthesis: the stereochemical course of β-lactam formation from chiral glycerol ingelesa
    non adierazia
    The role of molecular oxygen in clavulanic acid biosynthesis: evidence for a bacterial oxidative deamination ingelesa
    non adierazia
    Cloning, sequencing and disruption of a gene from Streptomyces clavuligerus involved in clavulanic acid biosynthesis ingelesa
    non adierazia
    A novel finding that Streptomyces clavuligerus can produce the antibiotic clavulanic acid using olive oil as a sole carbon source. ingelesa
    non adierazia
    Induction of holomycin production and complex metabolic changes by the argR mutation in Streptomyces clavuligerus NP1. ingelesa
    non adierazia
    Data set of in silico simulation for the production of clavulanic acid and cephamycin C by Streptomyces clavuligerus using a genome scale metabolic model ingelesa
    non adierazia
    Two sets of paralogous genes encode the enzymes involved in the early stages of clavulanic acid and clavam metabolite biosynthesis in Streptomyces clavuligerus ingelesa
    non adierazia
    A putative antimicrobial peptide from Hymenoptera in the megaplasmid pSCL4 of ATCC 27064 reveals a singular case of horizontal gene transfer with potential applications ingelesa
    non adierazia
    An improved HPLC-DAD method for clavulanic acid quantification in fermentation broths of Streptomyces clavuligerus. ingelesa
    non adierazia
    Coordination of glycerol utilization and clavulanic acid biosynthesis to improve clavulanic acid production in Streptomyces clavuligerus ingelesa
    non adierazia
    Homologous expression of lysA encoding diaminopimelic acid (DAP) decarboxylase reveals increased antibiotic production in Streptomyces clavuligerus ingelesa
    non adierazia
    The claR gene of Streptomyces clavuligerus, encoding a LysR-type regulatory protein controlling clavulanic acid biosynthesis, is linked to the clavulanate-9-aldehyde reductase (car) gene ingelesa
    non adierazia
    Mutants of Streptomyces clavuligerus with disruptions in different genes for clavulanic acid biosynthesis produce large amounts of holomycin: possible cross-regulation of two unrelated secondary metabolic pathways ingelesa
    non adierazia
    A pathway-specific transcriptional activator regulates late steps of clavulanic acid biosynthesis in Streptomyces clavuligerus ingelesa
    non adierazia
    Clavulanic acid production estimation based on color and structural features of Streptomyces clavuligerus bacteria using self-organizing map and genetic algorithm. ingelesa
    non adierazia
    Role of the cmcH-ccaR intergenic region and ccaR overexpression in cephamycin C biosynthesis in Streptomyces clavuligerus ingelesa
    non adierazia
    Genome-wide gene expression changes in an industrial clavulanic acid overproduction strain of Streptomyces clavuligerus ingelesa
    non adierazia
    Different proteins bind to the butyrolactone receptor protein ARE sequence located upstream of the regulatory ccaR gene of Streptomyces clavuligerus ingelesa
    non adierazia
    Proteome-wide alterations in an industrial clavulanic acid producing strain of Streptomyces clavuligerus ingelesa
    non adierazia
    Functional analysis of the gene encoding the clavaminate synthase 2 isoenzyme involved in clavulanic acid biosynthesis in Streptomyces clavuligerus ingelesa
    non adierazia
    Improvement of clavulanic acid production in Streptomyces clavuligerus by genetic manipulation of structural biosynthesis genes ingelesa
    non adierazia
    A statistical approach using L(25) orthogonal array method to study fermentative production of clavulanic acid by Streptomyces clavuligerus MTCC 1142. ingelesa
    non adierazia
    Genes specific for the biosynthesis of clavam metabolites antipodal to clavulanic acid are clustered with the gene for clavaminate synthase 1 in Streptomyces clavuligerus ingelesa
    non adierazia
    5S clavam biosynthetic genes are located in both the clavam and paralog gene clusters in Streptomyces clavuligerus. ingelesa
    non adierazia
    Clavulanic acid production by the MMS 150 mutant obtained from wild type Streptomyces clavuligerus ATCC 27064. ingelesa
    non adierazia
    In vivo functional analysis of a class A β-lactamase-related protein essential for clavulanic acid biosynthesis in Streptomyces clavuligerus ingelesa
    non adierazia
    Effect of water activity on production of beta-lactam antibiotics by Streptomyces clavuligerus in submerged culture ingelesa
    non adierazia
    5S clavam biosynthesis is controlled by an atypical two-component regulatory system in Streptomyces clavuligerus ingelesa
    non adierazia
    Improved production of clavulanic acid by reverse engineering and overexpression of the regulatory genes in an industrial Streptomyces clavuligerus strain ingelesa
    non adierazia
    Characterization of DNA-binding sequences for CcaR in the cephamycin-clavulanic acid supercluster of Streptomyces clavuligerus ingelesa
    non adierazia
    Streptomyces clavuligerus has a second copy of the proclavaminate amidinohydrolase gene ingelesa
    non adierazia
    Role of σ-factor (orf21) in clavulanic acid production in Streptomyces clavuligerus NRRL3585 ingelesa
    non adierazia
    Proteomics analysis of global regulatory cascades involved in clavulanic acid production and morphological development in Streptomyces clavuligerus ingelesa
    non adierazia
    Enhanced biosynthesis of clavulanic acid in Streptomyces clavuligerus due to oxidative challenge by redox-cycling agents ingelesa
    non adierazia
    High concentrations of clavulanic acid but not of its degradation products decrease glycerol consumption and oxygen uptake rates in cultures of Streptomyces clavuligerus ingelesa
    non adierazia
    Characterization of the Metabolic Response of Streptomyces clavuligerus to Shear Stress in Stirred Tanks and Single-Use 2D Rocking Motion Bioreactors for Clavulanic Acid Production ingelesa
    non adierazia
    Morphological differentiation and clavulanic acid formation are affected in a Streptomyces clavuligerus adpA-deleted mutant ingelesa
    non adierazia
    A comparison of the clavam biosynthetic gene clusters in Streptomyces antibioticus Tü1718 and Streptomyces clavuligerus ingelesa
    non adierazia
    Streptomyces clavuligerus shows a strong association between TCA cycle intermediate accumulation and clavulanic acid biosynthesis. ingelesa
    non adierazia
    Activation of Secondary Metabolite Gene Clusters in by the PimM Regulator of ingelesa
    non adierazia
    Draft genome sequence of Streptomyces clavuligerus NRRL 3585, a producer of diverse secondary metabolites. ingelesa
    non adierazia
    Expression of ccaR, encoding the positive activator of cephamycin C and clavulanic acid production in Streptomyces clavuligerus, is dependent on bldG. ingelesa
    non adierazia
    Dissociation of cephamycin C and clavulanic acid biosynthesis by 1,3-diaminopropane in Streptomyces clavuligerus. ingelesa
    non adierazia
    Production of clavulanic acid and cephamycin C by Streptomyces clavuligerus in palm-oil medium ingelesa
    non adierazia
    An approach to strain improvement and enhanced production of clavulanic acid in Streptomyces clavuligerus ingelesa
    non adierazia
    Improvement for the production of clavulanic acid by mutant Streptomyces clavuligerus ingelesa
    non adierazia
    Screening of medium constituents for clavulanic acid production by Streptomyces clavuligerus. ingelesa
    non adierazia
    A quantitative approach to characterizing cell lysis caused by mechanical agitation of Streptomyces clavuligerus. ingelesa
    non adierazia
    Expansion of the clavulanic acid gene cluster: identification and in vivo functional analysis of three new genes required for biosynthesis of clavulanic acid by Streptomyces clavuligerus ingelesa
    non adierazia
    Morphology and clavulanic acid production of Streptomyces clavuligerus: Effect of stirrer speed in batch fermentations ingelesa
    non adierazia
    Transcriptional Studies on a Streptomyces clavuligerus oppA2 Deletion Mutant: N-Acetylglycyl-Clavaminic Acid Is an Intermediate of Clavulanic Acid Biosynthesis ingelesa
    non adierazia
    Complete Genome Sequence of Streptomyces clavuligerus F613-1, an Industrial Producer of Clavulanic Acid ingelesa
    non adierazia
    The CagRS Two-Component System Regulates Clavulanic Acid Metabolism via Multiple Pathways in F613-1 ingelesa
    non adierazia
    An rplKDelta29-PALG-32 mutation leads to reduced expression of the regulatory genes ccaR and claR and very low transcription of the ceaS2 gene for clavulanic acid biosynthesis in Streptomyces clavuligerus ingelesa
    non adierazia
    Shear conditions in clavulanic acid production by Streptomyces clavuligerus in stirred tank and airlift bioreactors. ingelesa
    non adierazia
    Clavulanic acid production by Streptomyces clavuligerus: biogenesis, regulation and strain improvement ingelesa
    non adierazia
    The positive activator of cephamycin C and clavulanic acid production in Streptomyces clavuligerus is mistranslated in a bldA mutant ingelesa
    non adierazia
    Identification of the gene cluster for the dithiolopyrrolone antibiotic holomycin in Streptomyces clavuligerus ingelesa
    non adierazia
    Streptomyces clavuligerus relA-null mutants overproduce clavulanic acid and cephamycin C: negative regulation of secondary metabolism by (p)ppGpp ingelesa
    non adierazia
    Application of Acid and Cold Stresses to Enhance the Production of Clavulanic Acid by Streptomyces clavuligerus ingelesa
    non adierazia
    Clavulanic acid: a beta-lactamase-inhiting beta-lactam from Streptomyces clavuligerus ingelesa
    non adierazia
    Five additional genes are involved in clavulanic acid biosynthesis in Streptomyces clavuligerus. ingelesa
    non adierazia
    Enzymes catalyzing the early steps of clavulanic acid biosynthesis are encoded by two sets of paralogous genes in Streptomyces clavuligerus ingelesa
    osatuta
    karbono
    0 erreferentzia
    Commons-eko kategoria
    Clavulanic acid
    0 erreferentzia

    Identifikatzaileak

    Reaxys registry number ingelesa
    787059
    Erreferentzia bat
    non adierazia
    ChEBI ingelesa
    ChEBI-ren identifikatzailea
    48947
    lanaren edo izenaren hizkuntza
    ingeles
    izenburua
    clavulanic acid (ingelesa)
    sartze-data
    19 urria 2016
    UniChem compound ID ingelesa
    307121
    Erreferentzia bat
    non adierazia
    UniChem ingelesa
    DSSTOX compound identifier ingelesa
    DTXCID702830
    0 erreferentzia
    EC zenbakia
    261-069-2
    Erreferentzia bat
    non adierazia
    Global Substance Registration System ingelesa
    UNII
    23521W1S24
    lanaren edo izenaren hizkuntza
    ingeles
    izenburua
    clavulanic acid (ingelesa)
    sartze-data
    19 azaroa 2016
    ECHA Substance Infocard ID ingelesa
    100.055.500
    Erreferentzia bat
    non adierazia
    ECHA Substance Infocard database ingelesa
    ECHA Substance Infocard ID ingelesa
    100.055.500
    sartze-data
    27 abendua 2018
    izenburua
    Clavulanic acid (ingelesa)
    quotation ingelesa
    CAS no.: 58001-44-8 (ingelesa)
    RxNorm ID ingelesa
    48203
    Erreferentzia bat
    non adierazia
    NDF-RT ingelesa
    NDF-RT ID ingelesa
    N0000147772
    sartze-data
    26 otsaila 2018
    KNApSAcK ID ingelesa
    C00018091
    Erreferentzia bat
    non adierazia
    ChEBI ingelesa
    ChEBI-ren identifikatzailea
    48947
    lanaren edo izenaren hizkuntza
    ingeles
    izenburua
    clavulanic acid (ingelesa)
    sartze-data
    19 urria 2016
    Probes And Drugs ID ingelesa
    PD009731
    0 erreferentzia
    DrugCentral ID ingelesa
    669
    Erreferentzia bat
    non adierazia
    UniChem ingelesa
    PDB ligand ID ingelesa
    J01
    0 erreferentzia
    CAB ID ingelesa
    60862
    Erreferentzia bat
    non adierazia
    CAB Thesaurus ingelesa
    sartze-data
    6 apirila 2020
    PDB
    2XH9
    Erreferentzia bat
    non adierazia
    Protein Data Bank ingelesa
    PDB
    2XH9
    lanaren edo izenaren hizkuntza
    ingeles
    izenburua
    2XH9 (ingelesa)
    sartze-data
    19 urria 2016
    2XF3
    Erreferentzia bat
    non adierazia
    Protein Data Bank ingelesa
    PDB
    2XF3
    lanaren edo izenaren hizkuntza
    ingeles
    izenburua
    2XF3 (ingelesa)
    sartze-data
    19 urria 2016
    2XFS
    Erreferentzia bat
    non adierazia
    Protein Data Bank ingelesa
    PDB
    2XFS
    lanaren edo izenaren hizkuntza
    ingeles
    izenburua
    2XFS (ingelesa)
    sartze-data
    19 urria 2016
    2JAP
    Erreferentzia bat
    non adierazia
    Protein Data Bank ingelesa
    PDB
    2JAP
    lanaren edo izenaren hizkuntza
    ingeles
    izenburua
    2JAP (ingelesa)
    sartze-data
    19 urria 2016
     
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                  "https://www.wikidata.org/w/index.php?title=Q415709&oldid=2186676834"(e)tik jasota