How HLA-DM affects the peptide repertoire bound to HLA-DR molecules (Q41594025)

4 October 2017

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title

How HLA-DM affects the peptide repertoire bound to HLA-DR molecules (English)

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4 October 2017

Vogt AB

1

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4 October 2017

Kropshofer H

series ordinal

2

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4 October 2017

Hämmerling GJ

series ordinal

3

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4 October 2017

language of work or name

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1 May 1997

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4 October 2017

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4 October 2017

volume

54

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4 October 2017

issue

2

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4 October 2017

page(s)

170-179

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MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation

4 October 2017

cites work

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7 January 2021

Formation of a nine-subunit complex by HLA class II glycoproteins and the invariant chain

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7 January 2021

MHC class II-associated invariant chain contains a sorting signal for endosomal compartments

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7 January 2021

Intracellular transport of class II MHC molecules directed by invariant chain.

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7 January 2021

Proteolysis of the class II-associated invariant chain generates a peptide binding site in intracellular HLA-DR molecules

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7 January 2021

Endosomal aspartic proteinases are required for invariant-chain processing

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7 January 2021

HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides

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7 January 2021

The CLIP region of invariant chain plays a critical role in regulating major histocompatibility complex class II folding, transport, and peptide occupancy

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7 January 2021

The segment of invariant chain that is critical for association with major histocompatibility complex class II molecules contains the sequence of a peptide eluted from class II polypeptides

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7 January 2021

Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding

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7 January 2021

Homozygous deletions that simultaneously eliminate expressions of class I and class II antigens of EBV-transformed B-lymphoblastoid cells. I. Reduced proliferative responses of autologous and allogeneic T cells to mutant cells that have decreased ex

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7 January 2021

Molecular analysis of HLA class I and class II antigen loss mutants reveals a homozygous deletion of the DR, DQ, and part of the DP region: implications for class II gene order

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7 January 2021

Defective processing and presentation of exogenous antigens in mutants with normal HLA class II genes

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7 January 2021

Invariant chain peptides in most HLA-DR molecules of an antigen-processing mutant

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7 January 2021

In vivo and in vitro formation and dissociation of HLA-DR complexes with invariant chain-derived peptides

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7 January 2021

Self-release of CLIP in peptide loading of HLA-DR molecules

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7 January 2021

An essential role for HLA-DM in antigen presentation by class II major histocompatibility molecules

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7 January 2021

HLA-DMA and -DMB genes are both required for MHC class II/peptide complex formation in antigen-presenting cells

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7 January 2021

A new human HLA class II-related locus, DM

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7 January 2021

New class II-like genes in the murine MHC.

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7 January 2021

Limited polymorphism in HLA-DM does not involve the peptide binding groove

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7 January 2021

Antigen presentation: Kissing cousins exchange CLIP.

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7 January 2021

HLA-DM induces clip dissociation from MHC class II αβ dimers and facilitates peptide loading

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7 January 2021

HLA-DM acts as a molecular chaperone and rescues empty HLA-DR molecules at lysosomal pH

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7 January 2021

Accumulation of HLA-DM, a regulator of antigen presentation, in MHC class II compartments

1 reference

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7 January 2021

A lysosomal targeting signal in the cytoplasmic tail of the beta chain directs HLA-DM to MHC class II compartments.

1 reference

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7 January 2021

The MHC class II molecule H2-M is targeted to an endosomal compartment by a tyrosine-based targeting motif

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7 January 2021

Reconstitution of an operational MHC class II compartment in nonantigen-presenting cells

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7 January 2021

Mediation by HLA-DM of dissociation of peptides from HLA-DR

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7 January 2021

DM enhances peptide binding to class II MHC by release of invariant chain-derived peptide

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7 January 2021

A mutant human histocompatibility leukocyte antigen DR molecule associated with invariant chain peptides

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7 January 2021

Association between HLA-DM and HLA-DR in vivo

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7 January 2021

HLA-DM interactions with intermediates in HLA-DR maturation and a role for HLA-DM in stabilizing empty HLA-DR molecules

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7 January 2021

Kinetic analysis of peptide loading onto HLA-DR molecules mediated by HLA-DM.

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7 January 2021

Peptide binding and release by proteins implicated as catalysts of protein assembly

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7 January 2021

HLA-DM: an in vivo facilitator of MHC class II peptide loading

1 reference

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7 January 2021

Binding of major histocompatibility complex class II to the invariant chain-derived peptide, CLIP, is regulated by allelic polymorphism in class II.

1 reference

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7 January 2021

Enhanced dissociation of HLA-DR-bound peptides in the presence of HLA-DM

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7 January 2021

Structural intermediates in the reactions of antigenic peptides with MHC molecules.

1 reference

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7 January 2021

The generation of SDS-stable HLA DR dimers is independent of efficient peptide binding

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7 January 2021

Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

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7 January 2021

Promiscuous and allele-specific anchors in HLA-DR-binding peptides

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7 January 2021

Human histocompatibility leukocyte antigen (HLA)-DM edits peptides presented by HLA-DR according to their ligand binding motifs

1 reference

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7 January 2021

High-affinity binding of short peptides to major histocompatibility complex class II molecules by anchor combinations

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7 January 2021

Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles

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7 January 2021

Invariant chain and DM edit self-peptide presentation by major histocompatibility complex (MHC) class II molecules

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7 January 2021

How HLA-DM edits the MHC class II peptide repertoire: survival of the fittest?

1 reference

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7 January 2021

A structural transition in class II major histocompatibility complex proteins at mildly acidic pH.

1 reference

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7 January 2021

Evidence for a conformational change in a class II major histocompatibility complex molecule occurring in the same pH range where antigen binding is enhanced

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7 January 2021

MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding

1 reference

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7 January 2021

A role for peptide in determining MHC class II structure

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2897%2900077-3

7 January 2021

The human class II MHC protein HLA-DR1 assembles as empty alpha beta heterodimers in the absence of antigenic peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2897%2900077-3

7 January 2021

Peptide binding inhibits protein aggregation of invariant-chain free class II dimers and promotes surface expression of occupied molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2897%2900077-3

7 January 2021

Molecular chaperones: proteins essential for the biogenesis of some macromolecular structures

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2897%2900077-3

7 January 2021

The requirement for DM in class II-restricted antigen presentation and SDS-stable dimer formation is allele and species dependent.

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2897%2900077-3

7 January 2021

Selective release of some invariant chain-derived peptides from HLA-DR1 molecules at endosomal pH

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2897%2900077-3

7 January 2021

Structural features of the invariant chain fragment CLIP controlling rapid release from HLA-DR molecules and inhibition of peptide binding

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2897%2900077-3

7 January 2021

Invariant chain peptides enhancing or inhibiting the presentation of antigenic peptides by major histocompatibility complex class II molecules

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https://api.crossref.org/works/10.1016%2FS0198-8859%2897%2900077-3

7 January 2021

The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2897%2900077-3

7 January 2021

Antigen presentation mediated by recycling of surface HLA-DR molecules.

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2897%2900077-3

7 January 2021

10.1016/S0198-8859(97)00077-3

Identifiers

DOI

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4 October 2017

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