The von Hippel-Lindau Tumor Suppressor Protein Is Destabilized by Src: Implications for Tumor Angiogenesis and Progression (Q41612038)

5 October 2017

The von Hippel-Lindau Tumor Suppressor Protein Is Destabilized by Src: Implications for Tumor Angiogenesis and Progression (English)

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5 October 2017

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Mary T-H Chou

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5 October 2017

Josephine Anthony

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2

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5 October 2017

Jeffrey D Bjorge

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5 October 2017

Donald J Fujita

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5 October 2017

1 March 2010

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5 October 2017

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5 October 2017

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5 October 2017

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5 October 2017

225-238

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describes a project that uses

5 October 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3014987/fullTextXML

inferred from PubMed Central ID database lookup

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Src blockade stabilizes a Flk/cadherin complex, reducing edema and tissue injury following myocardial infarction

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Decreased Src tyrosine kinase activity inhibits malignant human ovarian cancer tumor growth in a nude mouse model.

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6 June 2018

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c-Src protein expression is increased in human breast cancer. An immunohistochemical and biochemical analysis

6 June 2018

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Germline mutations in the Von Hippel-Lindau disease (VHL) gene in families from North America, Europe, and Japan

6 June 2018

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Increased immunoreactivity and protein tyrosine kinase activity of the protooncogene pp60c-src in preneoplastic lesions in rat pancreas.

6 June 2018

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6 June 2018

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Insulin stimulates endothelin-1 secretion from human endothelial cells and modulates its circulating levels in vivo

6 June 2018

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Catalytic specificity of protein-tyrosine kinases is critical for selective signalling

6 June 2018

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c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism

6 June 2018

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Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation

6 June 2018

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Permanent cell line expressing human factor VIII-related antigen established by hybridization

6 June 2018

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Analysis of pp60c-src in human colon carcinoma and normal human colon mucosal cells.

6 June 2018

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Activation of the pp60c-src protein kinase is an early event in colonic carcinogenesis

6 June 2018

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A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

6 June 2018

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IL-6 is required for glioma development in a mouse model

6 June 2018

1 reference

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The pattern of enhancement of Src kinase activity on platelet-derived growth factor stimulation of glioblastoma cells is affected by the integrin engaged

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3014987

Germline mutations in the von Hippel-Lindau disease tumor suppressor gene: correlations with phenotype

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3014987

Activation of Src in human breast tumor cell lines: elevated levels of phosphotyrosine phosphatase activity that preferentially recognizes the Src carboxy terminal negative regulatory tyrosine 530

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3014987

Genotype-phenotype correlations in von Hippel-Lindau disease

2 December 2018

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12 December 2020

Overexpression and activation of the tyrosine kinase Src in human pancreatic carcinoma

1 reference

12 December 2020

Ran-mediated nuclear export of the von Hippel-Lindau tumor suppressor protein occurs independently of its assembly with cullin-2

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12 December 2020

p22 is a novel plasminogen fragment with antiangiogenic activity

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12 December 2020

Identifiers

DOI

10.1177/1947601910366719

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5 October 2017

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5 October 2017

PubMed publication ID

21212839

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