E2-EPF UCP targets pVHL for degradation and associates with tumor growth and metastasis (Q40259335)

19 September 2017

E2-EPF UCP targets pVHL for degradation and associates with tumor growth and metastasis (English)

1 reference

19 September 2017

Cho-Rok Jung

1

1 reference

19 September 2017

Kyung-Sun Hwang

2

1 reference

19 September 2017

Jinsang Yoo

3

1 reference

19 September 2017

Won-Kyung Cho

4

1 reference

19 September 2017

Jin-Man Kim

5

1 reference

19 September 2017

Woo Ho Kim

6

1 reference

19 September 2017

Dong-Soo Im

7

1 reference

19 September 2017

language of work or name

English

0 references

publication date

2 July 2006

1 reference

19 September 2017

1 reference

19 September 2017

12

1 reference

19 September 2017

7

1 reference

19 September 2017

809-816

1 reference

https://scigraph.springernature.com/pub.10.1038/nm1440

19 September 2017

0 references

cites work

The ubiquitin-proteasome pathway and pathogenesis of human diseases

1 reference

Mechanisms underlying ubiquitination

21 January 2018

1 reference

Analysis of gene expression profiles in normal and neoplastic ovarian tissue samples identifies candidate molecular markers of epithelial ovarian cancer

21 January 2018

1 reference

Overexpression, genomic amplification and therapeutic potential of inhibiting the UbcH10 ubiquitin conjugase in human carcinomas of diverse anatomic origin

21 January 2018

1 reference

Molecular basis of the VHL hereditary cancer syndrome

21 January 2018

1 reference

Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein

21 January 2018

1 reference

Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex

21 January 2018

1 reference

Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein

21 January 2018

1 reference

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

21 January 2018

1 reference

Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase

21 January 2018

1 reference

Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology

21 January 2018

1 reference

Regulation of angiogenesis by hypoxia: role of the HIF system

21 January 2018

1 reference

Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor.

21 January 2018

1 reference

Elongin BC complex prevents degradation of von Hippel-Lindau tumor suppressor gene products

21 January 2018

1 reference

Formation of the VHL-elongin BC tumor suppressor complex is mediated by the chaperonin TRiC.

21 January 2018

1 reference

A molecular basis for stabilization of the von Hippel-Lindau (VHL) tumor suppressor protein by components of the VHL ubiquitin ligase

21 January 2018

1 reference

Oncolytic effects of adenovirus mutant capable of replicating in hypoxic and normoxic regions of solid tumor

21 January 2018

1 reference

A conserved catalytic residue in the ubiquitin-conjugating enzyme family.

21 January 2018

1 reference

The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families

21 January 2018

1 reference

Suppressor of cytokine signaling-1 inhibits VAV function through protein degradation.

21 January 2018

1 reference

Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

21 January 2018

1 reference

Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo

21 January 2018

1 reference

A family of mammalian F-box proteins

21 January 2018

1 reference

Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects

21 January 2018

1 reference

Nuclear expression of hypoxia-inducible factor 1alpha protein is heterogeneous in human malignant cells under normoxic conditions

21 January 2018

1 reference

The subtle side to hypoxia inducible factor (HIFalpha) regulation

21 January 2018

1 reference

KiSS-1, a novel human malignant melanoma metastasis-suppressor gene

21 January 2018

1 reference

Tumour suppression by the human von Hippel-Lindau gene product

21 January 2018

1 reference

Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth

21 January 2018

1 reference

Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein

21 January 2018

1 reference

The contribution of VHL substrate binding and HIF1-alpha to the phenotype of VHL loss in renal cell carcinoma

21 January 2018

1 reference

Loss of pVHL is sufficient to cause HIF dysregulation in primary cells but does not promote tumor growth

21 January 2018

1 reference

HIF-1alpha induces cell cycle arrest by functionally counteracting Myc.

21 January 2018

1 reference

Decreased growth of Vhl-/- fibrosarcomas is associated with elevated levels of cyclin kinase inhibitors p21 and p27.

21 January 2018

1 reference

HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

21 January 2018

1 reference

Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

21 January 2018

1 reference

Genetic evidence for a tumor suppressor role of HIF-2alpha.

21 January 2018

1 reference

Adenovirus-mediated transfer of siRNA against PTTG1 inhibits liver cancer cell growth in vitro and in vivo

21 January 2018

1 reference

The arginine-1493 residue in QRRGRTGR1493G motif IV of the hepatitis C virus NS3 helicase domain is essential for NS3 protein methylation by the protein arginine methyltransferase 1.

21 January 2018

1 reference

Prmt5, which forms distinct homo-oligomers, is a member of the protein-arginine methyltransferase family

21 January 2018

1 reference

Differential localization of glucose transporter isoforms in non-polarized mammalian cells: distribution of GLUT1 but not GLUT3 to detergent-resistant membrane domains

21 January 2018

1 reference

Tumor suppressor protein VHL is induced at high cell density and mediates contact inhibition of cell growth

21 January 2018

1 reference

Characterization of a novel keratinocyte ubiquitin carrier protein

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Novel multiubiquitin chain linkages catalyzed by the conjugating enzymes E2EPF and RAD6 are recognized by 26 S proteasome subunit 5

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NM1440

1 reference

19 September 2017

1 reference