Mechanisms of transcriptional regulation of cellular genes by SV40 large T- and small T-antigens (Q41677060)

6 October 2017

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title

Mechanisms of transcriptional regulation of cellular genes by SV40 large T- and small T-antigens (English)

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6 October 2017

4

Rekvig OP

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6 October 2017

2

Seternes OM

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6 October 2017

Moens U

1

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PubMed ID

9421878

6 October 2017

Johansen B

series ordinal

3

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6 October 2017

1 January 1997

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6 October 2017

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6 October 2017

15

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6 October 2017

135-154

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6 October 2017

2

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https://scigraph.springernature.com/pub.10.1023/a:1007962908248

6 October 2017

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cites work

Loss of collagenase gene expression in immortalized clones of SV40 T antigen-transformed human diploid fibroblasts

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12 December 2020

SV40 large T antigen trans-activates the long terminal repeats of a large family of human endogenous retrovirus-like sequences

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12 December 2020

Cell specificity of transcription regulation by papovavirus T antigens and DNA replication

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12 December 2020

Phosphorylation of transcription factor p62TCF by MAP kinase stimulates ternary complex formation at c-fos promoter

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12 December 2020

Structure and function of simian virus 40 large tumor antigen

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12 December 2020

Repression of a G0-associated 65-kilodalton protein in actively proliferating and SV40-transformed mouse kidney cells

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12 December 2020

Modulation of the human papillomavirus type 16 induced transformation and transcription by deletion of loci on the short arm of human chromosome 11 can be mimicked by SV40 small t

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12 December 2020

An ATF/CREB binding motif is required for aberrant constitutive expression of the MHC class II DR alpha promoter and activation by SV40 T-antigen

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12 December 2020

SV40 large T inhibits myogenic differentiation partially through inducing c-jun

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12 December 2020

Dr1, a TATA-binding protein-associated phosphoprotein and inhibitor of class II gene transcription

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12 December 2020

The growth-stimulatory effect of simian virus 40 T antigen requires the interaction of insulinlike growth factor 1 with its receptor

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12 December 2020

The serum response element

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12 December 2020

The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein

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12 December 2020

Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations

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12 December 2020

Wild-type p53 activates transcription in vitro

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12 December 2020

Simian virus 40 (SV40) T-antigen transcriptional activation mediated through the Oct/SPH region of the SV40 late promoter

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12 December 2020

Simian virus 40 small-t does not transactivate RNA polymerase II promoters in virus infections

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12 December 2020

SV40 T-antigen-binding sites within the 5'-flanking regions of human U1 and U2 genes

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12 December 2020

Effect of the SV40 T antigen on the posttranscriptional regulation of the proliferating cell nuclear antigen and DNA polymerase-alpha genes

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12 December 2020

Differential regulation of myelin gene expression in SV40 T antigen-transfected rat glioma C6 cells

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12 December 2020

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

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12 December 2020

The helix-loop-helix protein rE12 and the C/EBP-related factor rNFIL-6 bind to neighboring sites within the c-fos serum response element

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12 December 2020

The requirement of simian virus 40 gene A product for the stimulation of cellular thymidine kinase activity after viral infection

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12 December 2020

Mutual functional antagonism of the simian virus 40 T antigen and the hepatitis B virus trans activator

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12 December 2020

Mapping the transcriptional transactivation function of simian virus 40 large T antigen

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12 December 2020

The Q300 gene: a novel transcription unit induced in simian virus 40-infected and -transformed mouse cells

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12 December 2020

Stimulation of RNA synthesis in isolated nuclei by partially purified preparations of simian virus 40 T-antigen

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12 December 2020

Activity of simian DNA-binding factors is altered in the presence of simian virus 40 (SV40) early proteins: characterization of factors binding to elements involved in activation of the SV40 late promoter

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12 December 2020

Modulation of HPV18 and BPV1 transcription in human keratinocytes by simian virus 40 large T antigen and adenovirus type 5 E1A antigen

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12 December 2020

An SV40 large T antigen binding site in the cellular genome is part of a cis-acting transcriptional element

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12 December 2020

SV40 stimulates expression of the transacting factor Sp1 at the mRNA level

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12 December 2020

Detection of activated c-H-ras oncogene in hepatocellular carcinomas developing in transgenic mice harboring albumin promoter-regulated simian virus 40 gene

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12 December 2020

Regulation of RNA polymerase III transcription in response to Simian virus 40 transformation

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12 December 2020

Reactivation of silent rRNA genes by simian virus 40 in human-mouse hybrid cells

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12 December 2020

Keratin gene expression in simian virus 40-transformed human keratinocytes

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12 December 2020

Constitutive synthesis of activator protein 1 transcription factor after viral transformation of mouse fibroblasts

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12 December 2020

Spontaneous losses of control of cytokeratin gene expression in transformed, non-epithelial human cells occurring at different levels of regulation.

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12 December 2020

Activation of the human epsilon- and beta-globin promoters by SV40 T antigen

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12 December 2020

SV40-induced expression of mouse gene 24p3 involves a post-transcriptional mechanism

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12 December 2020

Transcription factors AP-3 and AP-2 interact with the SV40 enhancer in a mutually exclusive manner

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12 December 2020

Abolition of mevinolin-induced growth inhibition in human fibroblasts following transformation by simian virus 40.

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12 December 2020

SV40 T-antigen as a dual oncogene: structure and function of the plasma membrane-associated population

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12 December 2020

The large tumor antigen of simian virus 40 encodes at least two distinct transforming functions

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12 December 2020

Expression level of the retinoblastoma susceptibility gene is elevated in simian virus 40-transformed cells.

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12 December 2020

Expression of enhanced levels of small RNA polymerase III transcripts encoded by the B2 repeats in simian virus 40-transformed mouse cells

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12 December 2020

Stimulation of the human heat shock protein 70 promoter in vitro by simian virus 40 large T antigen

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12 December 2020

Transforming growth factor alpha production and epidermal growth factor receptor expression in normal and oncogene transformed human mammary epithelial cells

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12 December 2020

Both upstream and intron sequence elements are required for elevated expression of the rat somatic cytochrome c gene in COS-1 cells

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12 December 2020

Simian virus 40 T antigen alters the binding characteristics of specific simian DNA-binding factors

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12 December 2020

trans activation of type 1 interferon promoters by simian virus 40 T antigen

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12 December 2020

Induction of proto-oncogene fos transcription through the adenylate cyclase pathway: characterization of a cAMP-responsive element

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12 December 2020

The regulation of cellular transcription by Simian virus 40 large T-antigen

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12 December 2020

Detection of cellular proteins associated with human adenovirus type 5 early region 1A polypeptides.

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12 December 2020

The long terminal repeat of the intracisternal A particle as a target for transactivation by oncogene products

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12 December 2020

Translatable mRNA for GP140 (a subunit of type VI collagen) is absent in SV40 transformed fibroblasts

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12 December 2020

Transient gene expression control: effects of transfected DNA stability and trans-activation by viral early proteins

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12 December 2020

Induction of cellular thymidine kinase occurs at the mRNA level

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12 December 2020

Isolation of cellular genes differentially expressed in mouse NIH 3T3 cells and a simian virus 40-transformed derivative: growth-specific expression of VL30 genes

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12 December 2020

trans Activation of the simian virus 40 enhancer

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12 December 2020

Stimulation of the adenovirus E2 promoter by simian virus 40 T antigen or E1A occurs by different mechanisms

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12 December 2020

Induction of specific transcription by RNA polymerase III in transformed cells

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12 December 2020

Regulation of c-myc and c-fos mRNA levels by polyomavirus: distinct roles for the capsid protein VP1 and the viral early proteins

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12 December 2020

Induction of c-Ha-ras transcription in rat cells by simian virus 40 large T antigen

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12 December 2020

Mitogenic and antimitogenic transforming growth factors secreted by adenovirus 2- and simian virus 40-transformed hamster cells: possible roles in promoting tumorigenesis

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12 December 2020

Positive and negative regulation of transcription in vitro: enhancer-binding protein AP-2 is inhibited by SV40 T antigen

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12 December 2020

Transforming but not immortalizing oncogenes activate the transcription factor PEA1

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12 December 2020

trans-activation of RNA polymerase II and III promoters by SV40 small t antigen

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12 December 2020

Evidence for transcriptional and post-transcriptional control of the cellular thymidine kinase gene

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12 December 2020

Histone synthesis in polyoma- and SV40-infected cells

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12 December 2020

Simian virus 40 induces the production of a polypeptide transforming factor(s)

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12 December 2020

Simian Virus 40 and Polyoma Virus Induce Synthesis of Heat Shock Proteins in Permissive Cells

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12 December 2020

Mutational analysis of simian virus 40 T antigen: stimulation of cellular DNA synthesis and activation of rRNA genes by mutants with deletions in the T-antigen gene

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12 December 2020

Regulation of human ribosomal RNA transcription

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12 December 2020

Activation of mouse genes in transformed cells

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12 December 2020

The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter

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12 December 2020

Production of platelet-derived growth factor-like molecules and reduced expression of platelet-derived growth factor receptors accompany transformation by a wide spectrum of agents

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12 December 2020

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12 December 2020

Expression of the human cGMP-dependent protein kinase II gene is lost upon introduction of SV40 T antigen or immortalization in human cells

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12 December 2020

SV40 T antigen inhibits expression of MyoD and myogenin, up-regulates Myf-5, but does not affect early expression of desmin or alpha 7 integrin during muscle development

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12 December 2020

Untransfected and SV40-transfected fetal and postnatal human thymic stromal cells. Analysis of phenotype, cytokine gene expression and cytokine production.

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12 December 2020

SV40 large T antigen with c-Jun down-regulates myelin P0 gene expression: a mechanism for papovaviral T antigen-mediated demyelination

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12 December 2020

Phosphorylation of transcription factors and control of the cell cycle

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12 December 2020

Immortalization of human fibroblasts by SV40 large T antigen results in the reduction of cyclin D1 expression and subunit association with proliferating cell nuclear antigen and Waf1.

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12 December 2020

Loss of heterozygosity of imprinted genes in SV40 t/T antigen-induced hepatocellular carcinomas

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12 December 2020

Deregulation of both imprinted and expressed alleles of the insulin-like growth factor 2 gene during beta-cell tumorigenesis

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12 December 2020

Failure of senescent human fibroblasts to express the insulin-like growth factor-1 gene

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12 December 2020

Purification and characterization of a protein kinase which is activated by SV40 large T-antigen and phosphorylates the tumor suppressor protein p53.

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12 December 2020

A TEF-1-independent mechanism for activation of the simian virus 40 (SV40) late promoter by mutant SV40 large T antigens

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12 December 2020

Increase in expression level of p21sdi1/cip1/waf1 with increasing division age in both normal and SV40-transformed human fibroblasts

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12 December 2020

Negative regulation of the neu promoter by the SV40 large T antigen.

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12 December 2020

A novel GTP-binding protein which is selectively repressed in SV40 transformed fibroblasts

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12 December 2020

E1A-associated p300 and CREB-associated CBP belong to a conserved family of coactivators

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12 December 2020

An E2F binding sequence negatively regulates the response of the insulin-like growth factor 1 (IGF-I) promoter to simian virus 40T antigen and to serum.

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12 December 2020

Transcriptional repression and activation in the same cell type of the human c-MYC promoter by the retinoblastoma gene protein: antagonisation of both effects by SV40 T antigen

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12 December 2020

Changes in promoter utilization in human and mouse c-myc genes upon transformation induction in temperature-sensitive cell lines

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12 December 2020

Simian virus 40 small tumor antigen inhibits dephosphorylation of protein kinase A-phosphorylated CREB and regulates CREB transcriptional stimulation

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12 December 2020

Simian virus 40 small t antigen cooperates with mitogen-activated kinases to stimulate AP-1 activity

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12 December 2020

SV40 large T antigen reinduces the cell cycle in terminally differentiated myotubes through inducing Cdk2, Cdc2, and their partner cyclins

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12 December 2020

Transrepression of RNA polymerase II promoters by the simian virus 40 small t antigen.

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12 December 2020

The c-fos cAMP-response element: regulation of gene expression by a beta 2-adrenergic agonist, serum and DNA methylation

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12 December 2020

Regulation of apoptosis in transgenic mice by simian virus 40 T antigen-mediated inactivation of p53.

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12 December 2020

DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relieve the cell's requirement for cyclin D1 function in G1

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12 December 2020

The transforming activity of simian virus 40 large tumor antigen

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12 December 2020

DRTF1/E2F: an expanding family of heterodimeric transcription factors implicated in cell-cycle control

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12 December 2020

Multiple, distinct trans-activation functions are encoded by the simian virus 40 large T and small t antigens, only some of which require the 82-residue amino-terminal common domain.

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12 December 2020

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

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12 December 2020

The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation.

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12 December 2020

Promoter-selective transcriptional defect in cell cycle mutant ts13 rescued by hTAFII250.

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12 December 2020

Suppression of tumorigenicity in simian virus 40-transformed 3T3 cells transfected with alpha-actinin cDNA.

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12 December 2020

Nuclear protein phosphatase 2A dephosphorylates protein kinase A-phosphorylated CREB and regulates CREB transcriptional stimulation

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12 December 2020

Regulation of the cellular thymidine kinase gene promoter in simian virus 40-infected cells

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12 December 2020

TIMP-2, a growth-stimulatory protein from SV40-transformed human fibroblasts

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12 December 2020

p53 and SV40 T antigen bind to the same region overlapping the conserved domain of the TATA-binding protein

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12 December 2020

Transcriptional activation by simian virus 40 large T antigen: requirements for simple promoter structures containing either TATA or initiator elements with variable upstream factor binding sites

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12 December 2020

Efficient transcriptional activation of many simple modular promoters by simian virus 40 large T antigen

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12 December 2020

Phosphorylated CREB binds specifically to the nuclear protein CBP

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12 December 2020

Modulation of cell growth, p34cdc2 and cyclin A levels by SV-40 large T antigen.

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12 December 2020

Transcriptional activation by simian virus 40 large T antigen: interactions with multiple components of the transcription complex

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12 December 2020

DNA tumor virus transforming proteins and the cell cycle

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12 December 2020

Regulation by tumour antigens defines a role for PP2A in signal transduction

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12 December 2020

The major transcriptional transactivation domain of simian virus 40 large T antigen associates nonconcurrently with multiple components of the transcriptional preinitiation complex

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12 December 2020

Interaction between T antigen and TEA domain of the factor TEF-1 derepresses simian virus 40 late promoter in vitro: identification of T-antigen domains important for transcription control

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12 December 2020

Retinoblastoma protein directly interacts with and activates the transcription factor NF-IL6

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12 December 2020

Suppression of platelet-derived growth factor alpha- and beta-receptor mRNA levels in human fibroblasts by SV40 T/t antigen

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12 December 2020

Noncoding control region of naturally occurring BK virus variants: sequence comparison and functional analysis

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12 December 2020

Reduced levels of alpha1(XI) procollagen mRNA in SV40-transformed cells

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12 December 2020

Regulation of gene expression by cGMP-dependent protein kinase. Transactivation of the c-fos promoter

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12 December 2020

In vivo expression of a single viral DNA-binding protein generates systemic lupus erythematosus-related autoimmunity to double-stranded DNA and histones

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12 December 2020

Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence

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12 December 2020

The SV40 large T antigen and adenovirus E1a oncoproteins interact with distinct isoforms of the transcriptional co-activator, p300.

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12 December 2020

Defective interleukin six expression and responsiveness in human mammary cells transformed by an adeno 5/SV40 hybrid virus.

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12 December 2020

TAF-like function of SV40 large T antigen

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12 December 2020

Differential expression of DNA polymerase alpha in normal and transformed human fibroblasts

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12 December 2020

SV40 Large T Antigen Interferes with Adult Myosin Heavy Chain Expression, but Not with Differentiation of Human Satellite Cells

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12 December 2020

SV40 large T antigen transactivates the human cdc2 promoter by inducing a CCAAT box binding factor

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12 December 2020

Association of p300 and CBP with simian virus 40 large T antigen

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12 December 2020

Time-sensitive reversal of hyperplasia in transgenic mice expressing SV40 T antigen

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12 December 2020

Activation of the human thymidine kinase (TK) promoter by simian virus 40 large T antigen requires both the T antigen pRb family-binding domain and TK promoter sequences resembling E2F-binding sites.

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12 December 2020

A growing coactivator network

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12 December 2020

A novel simian virus 40 early-region domain mediates transactivation of the cyclin A promoter by small-t antigen and is required for transformation in small-t antigen-dependent assays.

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12 December 2020

Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: the potential for multiplex signalling

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12 December 2020

c-Jun stimulates origin-dependent DNA unwinding by polyomavirus large Tantigen.

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12 December 2020

Induction of cyclin D1 by simian virus 40 small tumor antigen

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12 December 2020

SREBP transcriptional activity is mediated through an interaction with the CREB-binding protein

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12 December 2020

The general transcription factors of RNA polymerase II

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12 December 2020

p53, the cellular gatekeeper for growth and division

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12 December 2020

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12 December 2020

Involvement of co-activator p300 in the transcriptional regulation of the HER-2/neu gene

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12 December 2020

Regulation of RNA polymerases I and III by the retinoblastoma protein: a mechanism for growth control?

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12 December 2020

Neurocristopathy resembling neurofibromatosis type 1 in an NGF-SV40 transgenic line.

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12 December 2020

Experimental expression in mice and spontaneous expression in human SLE of polyomavirus T-antigen. A molecular basis for induction of antibodies to DNA and eukaryotic transcription factors

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12 December 2020

Identifiers

DOI

10.1023/A:1007962908248

1 reference

PubMed ID

9421878

Dimensions Publication ID

6 October 2017

0 references

1 reference

PubMed ID

9421878