Fixing ryanodine receptor Ca leak - a novel therapeutic strategy for contractile failure in heart and skeletal muscle. (Q41683737)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21113427%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Fixing ryanodine receptor Ca leak - a novel therapeutic strategy for contractile failure in heart and skeletal muscle (English)

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17 January 2020

1

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17 January 2020

author name string

Andrew R Marks

series ordinal

2

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17 January 2020

publication date

1 January 2010

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Drug discovery today. Disease mechanisms

17 January 2020

published in

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17 January 2020

volume

7

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17 January 2020

issue

2

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17 January 2020

page(s)

e151-e157

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Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophy

17 January 2020

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Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle

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Ryanodine receptor/calcium release channel PKA phosphorylation: a critical mediator of heart failure progression

6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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Enhancing calstabin binding to ryanodine receptors improves cardiac and skeletal muscle function in heart failure

6 June 2018

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Protection from cardiac arrhythmia through ryanodine receptor-stabilizing protein calstabin2.

6 June 2018

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Ca2+/calmodulin-dependent protein kinase II phosphorylation regulates the cardiac ryanodine receptor

6 June 2018

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Calcium/calmodulin-dependent protein kinase IIdelta associates with the ryanodine receptor complex and regulates channel function in rabbit heart.

6 June 2018

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Phospholamban: a crucial regulator of cardiac contractility

6 June 2018

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FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death

6 June 2018

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PKA phosphorylation activates the calcium release channel (ryanodine receptor) in skeletal muscle: defective regulation in heart failure

6 June 2018

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Ryanodine receptor calcium release channels

6 June 2018

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Cardiac excitation-contraction coupling

6 June 2018

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Phosphorylation-dependent regulation of ryanodine receptors: a novel role for leucine/isoleucine zippers

6 June 2018

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PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts

6 June 2018

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Survival of patients with a new diagnosis of heart failure: a population based study

6 June 2018

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Adverse consequences of high sympathetic nervous activity in the failing human heart

6 June 2018

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Stabilization of calcium release channel (ryanodine receptor) function by FK506-binding protein

6 June 2018

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Simulated calcium current can both cause calcium loading in and trigger calcium release from the sarcoplasmic reticulum of a skinned canine cardiac Purkinje cell

6 June 2018

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Mechanisms of calcium channel modulation by beta-adrenergic agents and dihydropyridine calcium agonists.

6 June 2018

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FK506 binding protein associated with the calcium release channel (ryanodine receptor)

6 June 2018

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6 June 2018

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Sparking the failing heart

18 August 2018

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Beta-blockers restore calcium release channel function and improve cardiac muscle performance in human heart failure.

18 August 2018

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FKBP12.6-mediated stabilization of calcium-release channel (ryanodine receptor) as a novel therapeutic strategy against heart failure

18 August 2018

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Affinity purification of the ryanodine receptor/calcium release channel from fast twitch skeletal muscle based on its tight association with FKBP12

18 August 2018

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12 December 2020

Skeletal Muscle Function and Its Relation to Exercise Tolerance in Chronic Heart Failure

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12 December 2020

Altered stoichiometry of FKBP12.6 versus ryanodine receptor as a cause of abnormal Ca(2+) leak through ryanodine receptor in heart failure

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12 December 2020

Effects of FK-506 on contraction and Ca2+ transients in rat cardiac myocytes

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12 December 2020

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12 December 2020

Effects of rapamycin on ryanodine receptor/Ca(2+)-release channels from cardiac muscle

1 reference

12 December 2020

Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure

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12 December 2020

10.1016/J.DDMEC.2010.09.009

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21113427%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21113427%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

21113427

1 reference