Sequence of neurodegeneration and accumulation of phosphorylated tau in cultured neurons after okadaic acid treatment (Q41695890)

7 October 2017

Sequence of neurodegeneration and accumulation of phosphorylated tau in cultured neurons after okadaic acid treatment (English)

1 reference

7 October 2017

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Kim D

1

1 reference

PubMed ID

10519048

7 October 2017

Su J

series ordinal

2

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PubMed ID

10519048

7 October 2017

Cotman CW

series ordinal

3

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7 October 2017

1 August 1999

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7 October 2017

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7 October 2017

839

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7 October 2017

2

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7 October 2017

253-262

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Role of abnormally phosphorylated tau in the breakdown of microtubules in Alzheimer disease

7 October 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Paired helical filament-like phosphorylation of tau, deposition of beta/A4-amyloid and memory impairment in rat induced by chronic inhibition of phosphatase 1 and 2A

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Phosphorylation of tau, Abeta-formation, and apoptosis after in vivo inhibition of PP-1 and PP-2A.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Okadaic acid induces early changes in microtubule-associated protein 2 and tau phosphorylation prior to neurodegeneration in cultured cortical neurons.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Neuropil threads are collinear with MAP2 immunostaining in neuronal dendrites of Alzheimer brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Abnormal phosphorylation of tau precedes ubiquitination in neurofibrillary pathology of Alzheimer disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Neuropathological stageing of Alzheimer-related changes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Synaptophysin and chromogranin A immunoreactivities in senile plaques of Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Dendritic Growth in the Aged Human Brain and Failure of Growth in Senile Dementia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Site-specific regulation of Alzheimer-like tau phosphorylation in living neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Induction of a specific tau Alzheimer epitope in SY-5Y neuroblastoma cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Beta-amyloid deposition and other measures of neuropathology predict cognitive status in Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

The phosphorylation state of the microtubule-associated protein tau as affected by glutamate, colchicine and beta-amyloid in primary rat cortical neuronal cultures

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

The biochemical pathway of neurofibrillary degeneration in aging and Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Dephosphorylation of tau protein and Alzheimer paired helical filaments by calcmeurin and phosphatase-2A

7 January 2021

2 references

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

inferred from DOI database lookup

7 January 2021

based on heuristic

Shift from fetal-type to Alzheimer-type phosphorylated Tau proteins in SKNSH-SY 5Y cells treated with okadaic acid.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Differential inhibition and posttranslational modification of protein phosphatase 1 and 2A in MCF7 cells treated with calyculin-A, okadaic acid, and tautomycin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Modulation of the phosphorylation state of tau in situ: the roles of calcium and cyclic AMP.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Region-specific stability of dendritic extent in normal human aging and regression in Alzheimer's disease. II. Subiculum

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Okadaic acid enhances abnormal phosphorylation on tau proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Tau phosphorylation in human, primate, and rat brain: evidence that a pool of tau is highly phosphorylated in vivo and is rapidly dephosphorylated in vitro.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Monoclonal antibody AT8 recognises tau protein phosphorylated at both serine 202 and threonine 205.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Phosphoprotein phosphatase activities in Alzheimer disease brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Dephosphorylation of Alzheimer's disease abnormally phosphorylated tau by protein phosphatase-2A.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Dephosphorylation of microtubule-associated protein tau by protein phosphatase-1 and -2C and its implication in Alzheimer disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Phosphatase activity toward abnormally phosphorylated tau: decrease in Alzheimer disease brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Region-specific stability of dendritic extent in normal human aging and regression in Alzheimer's disease. I. CA1 of hippocampus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Massive somatodendritic sprouting of cortical neurons in Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

A68: a major subunit of paired helical filaments and derivatized forms of normal Tau.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Phosphorylation-dependent epitopes of neurofilament antibodies on tau protein and relationship with Alzheimer tau

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Phosphorylation of tau in situ: inhibition of calcium-dependent proteolysis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Protein phosphatase inhibitors induce modification of synapse structure and tau hyperphosphorylation in cultured rat hippocampal neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Topographical distribution of synaptic-associated proteins in the neuritic plaques of Alzheimer's disease hippocampus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Microtubular reorganization and dendritic growth response in Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Neuritic pathology and dementia in Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Differential sensitivity to proteolysis by brain calpain of adult human tau, fetal human tau and PHF-tau

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Selective destruction of stable microtubules and axons by inhibitors of protein serine/threonine phosphatases in cultured human neurons.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Site-specific dephosphorylation of tau protein at Ser202/Thr205 in response to microtubule depolymerization in cultured human neurons involves protein phosphatase 2A.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Proline-directed and non-proline-directed phosphorylation of PHF-tau.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Alzheimer's disease: a re-examination of the amyloid hypothesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Recognition of Alzheimer paired helical filaments by monoclonal neurofilament antibodies is due to crossreaction with tau protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Neuropil threads of Alzheimer's disease show a marked alteration of the normal cytoskeleton

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Deposition of ?/A4 protein along neuronal plasma membranes in diffuse senile plaques

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

On the origin of Alzheimer's disease: a hypothesis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

In situ dephosphorylation of tau by protein phosphatase 2A and 2B in fetal rat primary cultured neurons.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Characterization of polyclonal antibodies to brain protein phosphatase 2A and immunohistochemical localization of the enzyme in rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Differential activities of protein phosphatase types 1 and 2A in cytosolic and particulate fractions from rat forebrain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Early phosphorylation of tau in Alzheimer's disease occurs at Ser-202 and is preferentially located within neurites.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Plaque biogenesis in brain aging and Alzheimer's disease. I. Progressive changes in phosphorylation states of paired helical filaments and neurofilaments

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Plaque biogenesis in brain aging and Alzheimer's disease. II. Progressive transformation and developmental sequence of dystrophic neurites

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

The regulation of phosphorylation of tau in SY5Y neuroblastoma cells: the role of protein phosphatases.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

The phosphatase inhibitor okadaic acid induces a phosphorylated paired helical filament tau epitope in human LA-N-5 neuroblastoma cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Dystrophic neurite formation associated with age-related beta amyloid deposition in the neocortex: clues to the genesis of neurofibrillary pathology.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Increased production of paired helical filament epitopes in a cell culture system reduces the turnover of tau

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Dephosphorylation of Alzheimer paired helical filaments by protein phosphatase-2A and -2B.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Dephosphorylation of fetal-tau and paired helical filaments-tau by protein phosphatases 1 and 2A and calcineurin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

Calpain-induced proteolysis of normal human tau and tau associated with paired helical filaments

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2899%2901724-2

10.1016/S0006-8993(99)01724-2

7 January 2021

Identifiers

DOI

1 reference

7 October 2017

1 reference

PubMed ID

10519048