FK506 and the role of immunophilins in nerve regeneration (Q41697821)

7 October 2017

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title

FK506 and the role of immunophilins in nerve regeneration (English)

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7 October 2017

Gold BG

1

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7 October 2017

1 December 1997

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7 October 2017

Molecular Neurobiology

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7 October 2017

15

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7 October 2017

3

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7 October 2017

285-306

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https://scigraph.springernature.com/pub.10.1007/bf02740664

7 October 2017

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cites work

FKBP51, a novel T-cell-specific immunophilin capable of calcineurin inhibition

1 reference

https://api.crossref.org/works/10.1007%2FBF02740664

Cyclosporin A, an inhibitor of calcineurin, impairs memory formation in day-old chicks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02740664

FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02740664

Cyclosporin A, FK-506, and rapamycin: pharmacologic probes of lymphocyte signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02740664

FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro

21 January 2018

1 reference

12 December 2020

The effect of a new immunosuppressive agent, FK-506, on xenogeneic neural transplantation in rodents

1 reference

12 December 2020

Immunophilins and nervous system

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12 December 2020

Association of a 59-kilodalton immunophilin with the glucocorticoid receptor complex

1 reference

12 December 2020

Transforming growth factor-beta 1 promotes re-elongation of injured axons of cultured rat hippocampal neurons

1 reference

12 December 2020

A nonimmunosuppressant FKBP-12 ligand increases nerve regeneration.

1 reference

12 December 2020

P59, an hsp 90-binding protein. Cloning and sequencing of its cDNA and preparation of a peptide-directed polyclonal antibody

1 reference

12 December 2020

Expression of nerve growth factor receptors by Schwann cells of axotomized peripheral nerves: ultrastructural location, suppression by axonal contact, and binding properties.

1 reference

12 December 2020

Regulation of free calmodulin levels by neuromodulin: neuron growth and regeneration

1 reference

12 December 2020

Neurotrophic immunophilin ligands stimulate structural and functional recovery in neurodegenerative animal models

1 reference

12 December 2020

Renal transplantation in baboons under FK 506

1 reference

12 December 2020

Alpha-MSH stimulates neurite outgrowth of neonatal rat corticospinal neurons in vitro.

1 reference

12 December 2020

A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin

1 reference

12 December 2020

An ACTH-(4-9) analogue, Org 2766, improves recovery from acrylamide neuropathy in rats.

1 reference

12 December 2020

Tests of the roles of two diffusible substances in long-term potentiation: evidence for nitric oxide as a possible early retrograde messenger

1 reference

12 December 2020

Nerve regeneration and serum levels of insulin-like growth factor-I in rats with streptozotocin-induced insulin deficiency

1 reference

12 December 2020

Studies on FK506 in experimental organ transplantation

1 reference

12 December 2020

Neuroprotective effect of FK506, an immunosuppressant, on transient global ischemia in gerbil.

1 reference

12 December 2020

A cdc2-like kinase distinct from cdk5 is associated with neurofilaments

1 reference

12 December 2020

Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia

1 reference

12 December 2020

Neurotrophic factors and regeneration in the peripheral nervous system

1 reference

12 December 2020

The immunosuppressive and toxic effects of FK-506 are mechanistically related: pharmacology of a novel antagonist of FK-506 and rapamycin

1 reference

12 December 2020

Suppressive effect of FK-506, a novel immunosuppressant, against MPTP-induced dopamine depletion in the striatum of young C57BL/6 mice.

1 reference

12 December 2020

Probing Immunosuppressant Action with a Nonnatural Immunophilin Ligand

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12 December 2020

The immunophilin FKBP12 functions as a common inhibitor of the TGF beta family type I receptors.

1 reference

12 December 2020

The Pittsburgh randomized trial of tacrolimus compared to cyclosporine for hepatic transplantation

1 reference

12 December 2020

Neuropathologic findings in liver transplantation: a comparative study of cyclosporine and FK 506

1 reference

12 December 2020

An FK506-sensitive transporter selectively decreases intracellular levels and potency of steroid hormones

1 reference

12 December 2020

Comparative dose-dependence study of FK506 and cyclosporin A on the rate of axonal regeneration in the rat sciatic nerve

1 reference

12 December 2020

Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

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12 December 2020

Guillain-Barré syndrome and parenteral gangliosides

1 reference

12 December 2020

One-year follow-up of an open-label trial of FK506 for primary kidney transplantation. A report of the U.S. Multicenter FK506 Kidney Transplant Group

1 reference

12 December 2020

FKBP12-FK506 complex inhibits phosphatase activity of two mammalian isoforms of calcineurin irrespective of their substrates or activation mechanisms

1 reference

12 December 2020

Discovery of FK-506 and update

1 reference

12 December 2020

Cyclosporin A, the cyclophilin class of peptidylprolyl isomerases, and blockade of T cell signal transduction

1 reference

12 December 2020

An inhibitory role of calcineurin in endocytosis of synaptic vesicles at nerve terminals of Drosophila larvae.

1 reference

12 December 2020

The side effects of FK 506 in humans

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12 December 2020

Nitric oxide facilitates long-term potentiation, but not long-term depression.

1 reference

12 December 2020

Specific interaction of type I receptors of the TGF-beta family with the immunophilin FKBP-12

1 reference

12 December 2020

Evidence that the Rate of Wallerian Degeneration is Controlled by a Single Autosomal Dominant Gene

1 reference

12 December 2020

Heterotopic heart transplantation in the rat receiving FK-506 alone or with cyclosporine

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12 December 2020

High brain densities of the immunophilin FKBP colocalized with calcineurin

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12 December 2020

A role for endothelial NO synthase in LTP revealed by adenovirus-mediated inhibition and rescue.

1 reference

12 December 2020

The calcium release channel of sarcoplasmic reticulum is modulated by FK-506-binding protein. Dissociation and reconstitution of FKBP-12 to the calcium release channel of skeletal muscle sarcoplasmic reticulum

1 reference

12 December 2020

Nimodipine accelerates axonal sprouting after surgical repair of rat facial nerve

1 reference

12 December 2020

Design, synthesis and structure of non-macrocyclic inhibitors of FKBP12, the major binding protein for the immunosuppressant FK506.

1 reference

12 December 2020

Org.2766 improves functional and electrophysiological aspects of regenerating sciatic nerve in the rat.

1 reference

12 December 2020

Immunophilin regulation of neurotransmitter release

1 reference

12 December 2020

Immunosuppression of canine, monkey, and baboon allografts by FK 506: with special reference to synergism with other drugs and to tolerance induction.

1 reference

12 December 2020

Acceleration by isaxonine of muscle reinnervation. Electrophysiological demonstration in leprotic neuropathy (author's transl)

1 reference

12 December 2020

Randomised trial comparing tacrolimus (FK506) and cyclosporin in prevention of liver allograft rejection. European FK506 Multicentre Liver Study Group

1 reference

12 December 2020

Structure comparison of native and mutant human recombinant FKBP12 complexes with the immunosuppressant drug FK506 (tacrolimus).

1 reference

12 December 2020

Impaired motor axon regeneration in the C57BL/Ola mouse

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12 December 2020

Insulin-like growth factor I (IGF-I) stimulates regeneration of the rat sciatic nerve

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12 December 2020

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1 reference

12 December 2020

Demyelinating sensorimotor polyneuropathy after administration of FK506

1 reference

12 December 2020

Effects of uridine in the treatment of diabetic neuropathy: an electrophysiological study

1 reference

12 December 2020

Anti-macrophage CR3 antibody blocks myelin phagocytosis by macrophages in vitro

1 reference

12 December 2020

Stabilization of calcium release channel (ryanodine receptor) function by FK506-binding protein

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12 December 2020

A three-hybrid system for detecting small ligand-protein receptor interactions

1 reference

12 December 2020

The cyclosporin A-binding immunophilin CyP-40 and the FK506-binding immunophilin hsp56 bind to a common site on hsp90 and exist in independent cytosolic heterocomplexes with the untransformed glucocorticoid receptor

1 reference

12 December 2020

Laminar and columnar organization of immunoreactivity for calcineurin, a calcium- and calmodulin-regulated protein phosphatase, in monkey striate cortex

1 reference

12 December 2020

Guillain-Barré syndrome after exogenous gangliosides in Italy

1 reference

12 December 2020

Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity

1 reference

12 December 2020

Effect of a new immunosuppressive agent, FK 506, on heterotopic cardiac allotransplantation in the rat

1 reference

12 December 2020

The immunosuppressant FK506 increases the rate of axonal regeneration in rat sciatic nerve

1 reference

12 December 2020

Axonally transported proteins associated with axon growth in rabbit central and peripheral nervous systems

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12 December 2020

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12 December 2020

The role of non-resident cells in Wallerian degeneration

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12 December 2020

An immunosuppressant, FK506, protects hippocampal neurons from forebrain ischemia in the mongolian gerbil.

1 reference

12 December 2020

Macrophage functional properties during myelin degradation.

1 reference

12 December 2020

FK506-induced neurotoxicity in liver transplantation

1 reference

12 December 2020

The hsp56 immunophilin component of untransformed steroid receptor complexes is localized both to microtubules in the cytoplasm and to the same nonrandom regions within the nucleus as the steroid receptor

1 reference

12 December 2020

Delayed wallerian degeneration in the central nervous system of Ola mice: an ultrastructural study

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12 December 2020

Dexamethasone enhances level of GAP-43 mRNA after nerve injury and facilitates re-projection of the hypoglossal nerve

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12 December 2020

Synaptic desensitization of NMDA receptors by calcineurin

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12 December 2020

The immunosuppressant FK506 and its nonimmunosuppressive analog L-685,818 are toxic to Cryptococcus neoformans by inhibition of a common target protein

1 reference

12 December 2020

Is cyclophilin involved in the immunosuppressive and nephrotoxic mechanism of action of cyclosporin A?

1 reference

12 December 2020

Overexpression, characterization, and purification of a recombinant mouse immunophilin FKBP-52 and identification of an associated phosphoprotein

1 reference

12 December 2020

Effect of immunosuppressant FK506 on ischemia-induced degeneration of hippocampal neurons in gerbils

1 reference

12 December 2020

Transforming growth factor-beta 1 stimulates expression of nerve growth factor in the rat CNS.

1 reference

12 December 2020

Asymmetric retraction of growth cone filopodia following focal inactivation of calcineurin

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12 December 2020

Immunosuppressant FK506 promotes neurite outgrowth in cultures of PC12 cells and sensory ganglia

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12 December 2020

Evidence that the 90-kDa heat shock protein (HSP90) exists in cytosol in heteromeric complexes containing HSP70 and three other proteins with Mr of 63,000, 56,000, and 50,000.

1 reference

12 December 2020

Structural and functional characterization of Escherichia coli peptidyl-prolyl cis-trans isomerases.

1 reference

12 December 2020

Evidence that Very Slow Wallerian Degeneration in C57BL/Ola Mice is an Intrinsic Property of the Peripheral Nerve

1 reference

12 December 2020

Insulin-like growth factor I increases myelination and inhibits demyelination in cultured organotypic nerve tissue.

1 reference

12 December 2020

Neurotoxicity after orthotopic liver transplantation. A comparison between cyclosporine and FK506.

1 reference

12 December 2020

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

1 reference

12 December 2020

Mechanism for isaxonine hepatitis. I. Metabolic activation by mouse and human cytochrome P-450

1 reference

12 December 2020

A Requirement for the Intercellular Messenger Nitric Oxide in Long-Term Potentiation

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12 December 2020

Gonadal steroids as promoting factors in axonal regeneration

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12 December 2020

Concerted regulation of protein phosphorylation and dephosphorylation by calmodulin

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12 December 2020

X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex

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12 December 2020

Hsp56: a novel heat shock protein associated with untransformed steroid receptor complexes

1 reference

12 December 2020

Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A

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12 December 2020

Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressive drugs FK506, rapamycin and cyclosporin A

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12 December 2020

Immunophilin FK506 binding protein associated with inositol 1,4,5-trisphosphate receptor modulates calcium flux

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12 December 2020

A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase

1 reference

12 December 2020

The effect of ACTH4-10 on protein synthesis, actin and tubulin during regeneration.

1 reference

12 December 2020

Alteration of ryanodine receptor in the hippocampus CA1 after hemispheric cerebral ischemia.

1 reference

12 December 2020

Impaired nerve regeneration in streptozotocin-diabetic rats is improved by treatment with gangliosides.

1 reference

12 December 2020

A facilitatory effect on the induction of long-term potentiation in vivo by chronic administration of antisense oligodeoxynucleotides against catalytic subunits of calcineurin

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12 December 2020

Neuroprotective actions of FK506 in experimental stroke: in vivo evidence against an antiexcitotoxic mechanism.

1 reference

12 December 2020

Sensory nerves in adult rats regenerate and restore sensory function to the skin independently of endogenous NGF

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12 December 2020

Cyclophilin 40 (CyP-40), mapping of its hsp90 binding domain and evidence that FKBP52 competes with CyP-40 for hsp90 binding

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12 December 2020

Rat hippocampal neurons in dispersed cell culture.

1 reference

12 December 2020

Endogenous nitric oxide release required for long-term synaptic depression in the cerebellum

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12 December 2020

ACTH accelerates recovery of neuromuscular function following crushing of peripheral nerve

1 reference

12 December 2020

The immunosuppressant FK506 ameliorates ischaemic damage in the rat brain.

1 reference

12 December 2020

Nitric oxide donors enhance neurotrophin-induced neurite outgrowth through a cGMP-dependent mechanism.

1 reference

12 December 2020

Cyclosporin A attenuates degeneration of dopaminergic neurons induced by 6-hydroxydopamine in the mouse brain.

1 reference

12 December 2020

Axonal growth-associated proteins

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12 December 2020

Neuronal regeneration enhances the expression of the immunophilin FKBP-12

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12 December 2020

GAP-43 as a 'calmodulin sponge' and some implications for calcium signalling in axon terminals

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12 December 2020

Axonal regeneration of sensory nerves is delayed by continuous intrathecal infusion of nerve growth factor

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12 December 2020

A Comparison of Tacrolimus (FK 506) and Cyclosporine for Immunosuppression in Liver Transplantation

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12 December 2020

FK 506 for liver, kidney, and pancreas transplantation

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12 December 2020

Immunosuppressant FK506 prevents mossy fiber sprouting induced by kindling stimulation

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12 December 2020

Systemic administration of rhIGF-I enhanced regeneration after sciatic nerve crush in mice

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12 December 2020

Thermal stability and folding of the collagen triple helix and the effects of mutations in osteogenesis imperfecta on the triple helix of type I collagen

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12 December 2020

Discovering high-affinity ligands for proteins: SAR by NMR

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12 December 2020

The immunosuppressant FK506 increases functional recovery and nerve regeneration following peripheral nerve injury

1 reference

12 December 2020

FK506 (tacrolimus) compared with cyclosporine for primary immunosuppression after pediatric liver transplantation. Results from the U.S. Multicenter Trial.

1 reference

12 December 2020

FKBP-12 recognition is dispensable for signal generation by type I transforming growth factor-beta receptors.

1 reference

12 December 2020

Characterization of high molecular weight FK-506 binding activities reveals a novel FK-506-binding protein as well as a protein complex

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12 December 2020

Reduction of calcineurin enzymatic activity in Alzheimer's disease: correlation with neuropathologic changes.

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12 December 2020

Tyrosine phosphorylation in early embryonic growth cones.

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12 December 2020

Macrophage systems in peripheral nerves. A review.

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12 December 2020

Stimulation by ACTH4-10 of nerve fiber regeneration following sciatic nerve crush

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12 December 2020

The mechanism of action of cyclosporin A and FK506

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12 December 2020

The use of FK-506 for small intestine allotransplantation. Inhibition of acute rejection and prevention of fatal graft-versus-host disease

1 reference

12 December 2020

Effects of corticotrophin (ACTH) on recovery of sensorimotor function in the rat: Structure-activity study

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12 December 2020

Bovine gangliosides and acute motor polyneuropathy

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12 December 2020

Changes in axonally transported proteins during axon regeneration in toad retinal ganglion cells

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12 December 2020

Only 'de novo' long-term depression (LTD) in the rat hippocampus in vitro is blocked by the same low concentration of FK506 that blocks LTD in the visual cortex.

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12 December 2020

Orthotopic liver transplantation in dogs receiving FK-506.

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12 December 2020

The mechanism of action of FK-506 and cyclosporin A.

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12 December 2020

Monoclonal antibodies show that kinase C phosphorylation of GAP-43 during axonogenesis is both spatially and temporally restricted in vivo

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12 December 2020

The immunosuppressant FK506 selectively inhibits expression of early T cell activation genes

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12 December 2020

Effects of an inhibitor for calcium/calmodulin-dependent protein phosphatase, calcineurin, on induction of long-term potentiation in rat visual cortex.

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12 December 2020

Calcineurin associated with the inositol 1,4,5-trisphosphate receptor-FKBP12 complex modulates Ca2+ flux

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12 December 2020

An inhibitor for calcineurin, FK506, blocks induction of long-term depression in rat visual cortex.

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12 December 2020

Transcription of IL-2 and IL-4 genes is not inhibited by cyclosporin A in competent T cells

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12 December 2020

Molecular mechanisms of immunosuppression by cyclosporine, FK506, and rapamycin

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12 December 2020

The cytosolic-binding protein for the immunosuppressant FK-506 is both a ubiquitous and highly conserved peptidyl-prolyl cis-trans isomerase

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF02740664

1 reference

PubMed ID

9457703

Dimensions Publication ID

7 October 2017

0 references

1 reference

PubMed ID

9457703