Molecular and cellular mechanisms of T lymphocyte apoptosis (Q41722123)

8 October 2017

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title

Molecular and cellular mechanisms of T lymphocyte apoptosis (English)

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8 October 2017

Molecular and Cellular Mechanisms of T Lymphocyte Apoptosis (English)

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2

Guido Kroemer

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Josef Penninger

series ordinal

1

object named as

Josef M. Penninger

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Josef Penninger

series ordinal

1

object named as

Penninger JM

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8 October 2017

2

Kroemer G

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8 October 2017

1 January 1998

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8 October 2017

1998

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published in

Advances in Immunology

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8 October 2017

68

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8 October 2017

51-144

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Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

8 October 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Apoptosis in the pathogenesis and treatment of disease

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https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Apoptosis without decrease of cell DNA content

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Presence of double-strand breaks with single-base 3' overhangs in cells undergoing apoptosis but not necrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Utilization of an in vitro assay to evaluate chromatin degradation by candidate apoptotic nucleases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Mg2+- or Mn2+-dependent endonuclease activities of human myeloid leukemia cells capable of producing nucleosomal-size DNA fragmentation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Identification of a novel 97 kDa endonuclease capable of internucleosomal DNA cleavage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Endonuclease G from mammalian nuclei is identical to the major endonuclease of mitochondria

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https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Resistance of mitochondrial DNA to degradation characterizes the apoptotic but not the necrotic mode of human leukemia cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Native recombinant cyclophilins A, B, and C degrade DNA independently of peptidylprolyl cis-trans-isomerase activity. Potential roles of cyclophilins in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Bcl-2 inhibits the mitochondrial release of an apoptogenic protease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Cleavage of actin by interleukin 1 beta-converting enzyme to reverse DNase I inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Chromatin condensation during apoptosis requires ATP.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Human Bak induces cell death in Schizosaccharomyces pombe with morphological changes similar to those with apoptosis in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

CED-4 induces chromatin condensation in Schizosaccharomyces pombe and is inhibited by direct physical association with CED-9.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Death of germinal center B cells without DNA fragmentation

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https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Cell nucleus and DNA fragmentation are not required for apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Zinc inhibits apoptosis upstream of ICE/CED-3 proteases rather than at the level of an endonuclease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The apoptosis endonucleases: cleaning up after cell death?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Purification and characterization of Mycoplasma penetrans Ca2+/Mg2+-dependent endonuclease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Glucocorticoid-mediated control of the activation and clonal deletion of peripheral T cells in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

T-cell apoptosis detected in situ during positive and negative selection in the thymus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

ICE family proteases: mediators of all apoptotic cell death?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The cell-death machine

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https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

1 reference

7 January 2021

Involvement of cellular proteolytic machinery in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Apoptosis by a cytosolic extract from Fas-activated cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

FLICE Induced Apoptosis in a Cell-free System

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Ceramide induces apoptosis via CPP32 activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Activation of Multiple Interleukin-1β Converting Enzyme Homologues in Cytosol and Nuclei of HL-60 Cells during Etoposide-induced Apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Increased expression of the insulin-like growth factor-II gene in Wilms' tumor is not dependent on loss of genomic imprinting or loss of heterozygosity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The interleukin-1 beta-converting enzyme (ICE) is localized on the external cell surface membranes and in the cytoplasmic ground substance of human monocytes by immuno-electron microscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Caspase-3-mediated cleavage of protein kinase C theta in induction of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

A pre-existing protease is a common effector of thymocyte apoptosis mediated by diverse stimuli

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

An ICE-like protease is a common mediator of apoptosis induced by diverse stimuli in human monocytic THP.1 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

A cleavage-site-directed inhibitor of interleukin-1 beta-converting enzyme-like proteases inhibits apoptosis in primary cultures of rat hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone (Z-VAD.FMK) inhibits apoptosis by blocking the processing of CPP32.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Role of Ced-3/ICE-family proteases in staurosporine-induced programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Different interleukin-1 beta converting enzyme (ICE) family protease requirements for the apoptotic death of T lymphocytes triggered by diverse stimuli

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Suppression of apoptosis by nitric oxide via inhibition of interleukin-1beta-converting enzyme (ICE)-like and cysteine protease protein (CPP)-32-like proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Apoptosis in the absence of poly-(ADP-ribose) polymerase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Resistance of actin to cleavage during apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Lamin proteolysis facilitates nuclear events during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Target cell lysis by CTL granule exocytosis is independent of ICE/Ced-3 family proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Fas activation of the p38 mitogen-activated protein kinase signalling pathway requires ICE/CED-3 family proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Cytokine response modifier A (CrmA) inhibits ceramide formation in response to tumor necrosis factor (TNF)-alpha: CrmA and Bcl-2 target distinct components in the apoptotic pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Bcl-2 down-regulates the activity of transcription factor NF-kappaB induced upon apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

DNA fragmentation induced by protease activation in p53-null human leukemia HL60 cells undergoing apoptosis following treatment with the topoisomerase I inhibitor camptothecin: cell-free system studies

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Apoptosis induction resulting from proteasome inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Peptidyl aldehyde inhibitors of proteasome induce apoptosis rapidly in mouse lymphoma RVC cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Effect of Protease Inhibitors on Early Events of Apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Calpain inhibitors and serine protease inhibitors can produce apoptosis in HL-60 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Two Different Proteases Are Involved in the Proteolysis of Lamin during Apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Altered lipid packing identifies apoptotic thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Exposure of phosphatidylethanolamine on the surface of apoptotic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Phosphatidylserine externalization during CD95-induced apoptosis of cells and cytoplasts requires ICE/CED-3 protease activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Involvement of extracellular calcium in phosphatidylserine exposure during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

A subfamily of P-type ATPases with aminophospholipid transporting activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Mechanisms of phosphatidylserine exposure, a phagocyte recognition signal, on apoptotic T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Reconstitution of phospholipid scramblase activity from human blood platelets

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Isolation of an erythrocyte membrane protein that mediates Ca2+-dependent transbilayer movement of phospholipid

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Protease Involvement in Fodrin Cleavage and Phosphatidylserine Exposure in Apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Rapid and specific efflux of reduced glutathione during apoptosis induced by anti-Fas/APO-1 antibody

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Absence of volume regulatory mechanisms contributes to the rapid activation of apoptosis in thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Phagocyte recognition of cells undergoing apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: implications for coagulation events and antigenic spread in systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Non-oxidative loss of glutathione in apoptosis via GSH extrusion.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Protease activation during apoptosis: death by a thousand cuts?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Constitutive expression of the machinery for programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

How the lambda repressor and cro work

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Inhibition of Nur77/Nurr1 leads to inefficient clonal deletion of self-reactive T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Apoptosis and programmed cell death in immunity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Protein or RNA synthesis inhibition induces apoptosis of mature human CD4+ T cell blasts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Induction of apoptosis in fibroblasts by c-myc protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Regulation of cell division cycle progression by bcl-2 expression: a potential mechanism for inhibition of programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The cell death inhibitor Bcl-2 and its homologues influence control of cell cycle entry

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

p53 in signaling checkpoint arrest or apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

T cells from baxalpha transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA damage-induced cell death in the absence of p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

E2F-1 functions in mice to promote apoptosis and suppress proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Detection of apoptosis and DNA replication by differential labeling of DNA strand breaks with fluorochromes of different color

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The target cell nucleus is not required for cell-mediated granzyme- or Fas-based cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

No requirement of reactive oxygen intermediates in Fas‐mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Programmed cell death and Bcl-2 protection in very low oxygen.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The role of oxygen in thymocyte apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Calcium-activated DNA fragmentation kills immature thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Lack of correlation between early intracellular calcium ion rises and the onset of apoptosis in thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Intracellular calcium stores are not required for Bcl-2-mediated protection from apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Calcium-dependent, interleukin 1-converting enzyme inhibitor-insensitive degradation of lamin B1 and DNA fragmentation in isolated thymocyte nuclei

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Mitochondrial control of nuclear apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Apoptosis induced in Jurkat cells by several agents is preceded by intracellular acidification

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Events in apoptosis. Acidification is downstream of protease activation and BCL-2 protection

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The temporal relationship between protein phosphatase, ICE/CED-3 proteases, intracellular acidification, and DNA fragmentation in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

A novel human protease similar to the interleukin-1 beta converting enzyme induces apoptosis in transfected cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Identification of a cysteine protease closely related to interleukin-1 beta-converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Proteolytic activation of the cell death protease Yama/CPP32 by granzyme B.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Cytotoxic T-cell-derived granzyme B activates the apoptotic protease ICE-LAP3

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Evidence for CPP32 activation in the absence of apoptosis during T lymphocyte stimulation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Bcl-x(L) can inhibit apoptosis in cells that have undergone Fas-induced protease activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The mitochondrial death/life regulator in apoptosis and necrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Acute myocardial infarction in humans is associated with activation of programmed myocyte cell death in the surviving portion of the heart

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Expression of bcl-2 inhibits necrotic neural cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Mitochondrial control of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Mitochondrial implication in apoptosis. Towards an endosymbiont hypothesis of apoptosis evolution

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The proto-oncogene Bcl-2 and its role in regulating apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Bcl-x(L) forms an ion channel in synthetic lipid membranes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Channel formation by antiapoptotic protein Bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Checkpoints of dueling dimers foil death wishes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Bcl-2 and the regulation of programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Regulation of lymphocyte survival by the bcl-2 gene family

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Biogenesis of mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Mitochondrial perturbations define lymphocytes undergoing apoptotic depletion in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Protective Effect of N-Acetylcysteine in Tumor Necrosis Factor-α-Induced Apoptosis in U937 Cells: The Role of Mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Mitochondria are selective targets for the protective effects of heat shock against oxidative injury

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Mitochondrial permeability transition is a central coordinating event of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Redox regulation of apoptosis: impact of thiol oxidation status on mitochondrial function.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Detection of apoptosis in live cells by MitoTracker red CMXRos and SYTO dye flow cytometry

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Chloromethyl-X-Rosamine is an aldehyde-fixable potential-sensitive fluorochrome for the detection of early apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Release of cytochrome c from liver mitochondria during permeability transition.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Isolation of the mitochondrial benzodiazepine receptor: association with the voltage-dependent anion channel and the adenine nucleotide carrier

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The mitochondrial permeability transition.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The permeability transition pore as a mitochondrial calcium release channel: a critical appraisal

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Mitochondrial ADP/ATP carrier can be reversibly converted into a large channel by Ca2+

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Complexes between kinases, mitochondrial porin and adenylate translocator in rat brain resemble the permeability transition pore.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Perspectives on the mitochondrial multiple conductance channel

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Modulation of the mitochondrial permeability transition pore by pyridine nucleotides and dithiol oxidation at two separate sites.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Peroxynitrite causes calcium efflux from mitochondria which is prevented by Cyclosporin A.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

On the effects of paraquat on isolated mitochondria. Evidence that paraquat causes opening of the cyclosporin A-sensitive permeability transition pore synergistically with nitric oxide.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Nitric oxide induces apoptosis via triggering mitochondrial permeability transition.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Ceramide induces hepatocyte cell death through disruption of mitochondrial function in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The peptide mastoparan is a potent facilitator of the mitochondrial permeability transition

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Tim23, a protein import component of the mitochondrial inner membrane, is required for normal activity of the multiple conductance channel, MCC.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Ca2+ depletion prevents anoxic death of hepatocytes by inhibiting mitochondrial permeability transition.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Mitochondrial dysfunction is a primary event in glutamate neurotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Cyclosporin A delays mitochondrial depolarization induced by N-methyl-D-aspartate in cortical neurons: evidence of the mitochondrial permeability transition

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The cytotoxicity of tumor necrosis factor depends on induction of the mitochondrial permeability transition

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Bcl-2 targets the protein kinase Raf-1 to mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Role of tyrosine phosphorylation of HS1 in B cell antigen receptor-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Identification of genes induced during apoptosis in T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Loss of function of cytochrome c in Jurkat cells undergoing fas-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Protection by cyclosporin A of cultured hepatocytes from the toxic consequences of the loss of mitochondrial energization produced by 1-methyl-4-phenylpyridinium

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Contribution of the mitochondrial permeability transition to lethal injury after exposure of hepatocytes to t-butylhydroperoxide

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Translocation of apocytochrome c across the outer membrane of mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The ADP-ATP translocation in mitochondria, a membrane potential controlled transport

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

ATP flux is controlled by a voltage-gated channel from the mitochondrial outer membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Inhibition of anoxia-induced injury in heart myocytes by cyclosporin A

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Mitochondrial depolarization in glutamate-stimulated neurons: an early signal specific to excitotoxin exposure

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The mitochondrial membrane permeability transition induced by inorganic phosphate or inorganic arsenate. A comparative study

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Mitochondrial implication in accidental and programmed cell death: apoptosis and necrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

A mitochondrial signal peptide from Neurospora crassa increases the permeability of isolated rat liver mitochondria.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The permeability transition pore. Control points of a cyclosporin A-sensitive mitochondrial channel involved in cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Superoxide production by the mitochondrial respiratory chain

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

T cell selection in the thymus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The thymic microenvironment.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Signal transduction, mitotic catastrophes, and death in T-cell development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

CD4/CD8 lineage commitment: back to instruction?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

T cell tolerance by clonal elimination in the thymus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

p53 is required for radiation-induced apoptosis in mouse thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Thymocyte apoptosis induced by p53-dependent and independent pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Impaired Negative Selection of T Cells in Hodgkin's Disease Antigen CD30–Deficient Mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

A possible role for bcl-2 in regulating T-cell memory--a 'balancing act' between cell death and survival

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The progressive differentiation of primed T cells is associated with an increasing susceptibility to apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Activation-induced apoptosis in lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Receptor-stimulated death pathway is opened by antigen in mature T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Induction of apoptosis in mature T cells by tumour necrosis factor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The roles of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Tumor necrosis factor receptor p55 mediates deletion of peripheral cytotoxic T lymphocytesin vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Propriocidal apoptosis of mature T lymphocytes occurs at S phase of the cell cycle.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The fail-safe paradigm of immunological self-tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

T cell antigen receptor activation pathways: The tyrosine kinase connection

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The role of p56lck and p59fyn tyrosine kinases and CD45 protein tyrosine phosphatase in T-cell development and clonal selection

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Complex complexes: signaling at the TCR.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Transmission of signals from the T lymphocyte antigen receptor to the genes responsible for cell proliferation and immune function: the missing link

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Requirement for association of p56lck with CD4 in antigen-specific signal transduction in T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Product of vav proto-oncogene defines a new class of tyrosine protein kinase substrates

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

A tale of two messengers

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The regulation and function of p21ras in T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

JNK is involved in signal integration during costimulation of T lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Both immature and mature T cells mobilize Ca2+ in response to antigen receptor crosslinking

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

T-cell development and transmembrane signaling: changing biological responses through an unchanging receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Activation events during thymic selection

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Programmed death of autoreactive thymocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Tyrosine kinase triggering in thymocytes undergoing positive selection

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

In vivo calcium elevations in thymocytes with T cell receptors that are specific for self ligands

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Circadian rhythm and light regulate opsin mRNA in rod photoreceptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Intracellular signals that mediate thymic negative selection

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Cyclosporin A inhibits activation-induced cell death in T-cell hybridomas and thymocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Disruption of T cell development and repertoire selection by calcineurin inhibition in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

In vivo and in vitro clonal deletion of double-positive thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Lymphocyte apoptosis: mediation by increased type 3 inositol 1,4,5-trisphosphate receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Regulation of the inositol 1,4,5-trisphosphate receptor by tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Signaling for death of lymphoid cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Death of mature T cells by separate ligation of CD4 and the T-cell receptor for antigen

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Disruption of CD8-dependent negative and positive selection of thymocytes is correlated with a decreased association between CD8 and the protein tyrosine kinase, p56lck

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Profound block in thymocyte development in mice lacking p56lck

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

CD4 expression is differentially required for deletion of MLS-1a-reactive T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

T cell repertoire and clonal deletion of Mtv superantigen-reactive T cells in mice lacking CD4 and CD8 molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Essential role for ZAP-70 in both positive and negative selection of thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Temporal phases in apoptosis defined by the actions of Src homology 2 domains, ceramide, Bcl-2, interleukin-1beta converting enzyme family proteases, and a dense membrane fraction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Crk is required for apoptosis in Xenopus egg extracts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Hyporesponsiveness of "naive" (CD45RA+) human T cells to multiple receptor-mediated stimuli but augmentation of responses by co-stimuli.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

CD45: an emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

CD45RA antibodies split the CD3bright T cell subset

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

CD45RA and CD45RBhigh expression induced by thymic selection events

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Changes in CD45 isoform expression accompany antigen-induced murine T-cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Regulation of TCR signaling by CD45 lacking transmembrane and extracellular domains

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Rescue of signaling by a chimeric protein containing the cytoplasmic domain of CD45.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Identification of an alternative CTLA-4 ligand costimulatory for T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Human thymic epithelial cells express an endogenous lectin, galectin-1, which binds to core 2 O-glycans on thymocytes and T lymphoblastoid cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Apoptosis of T cells mediated by galectin-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Anchorage dependence, integrins, and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Induction of programmed cell death in human hematopoietic cell lines by fibronectin via its interaction with very late antigen 5.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Constitutive activation of integrin alpha 4 beta 1 defines a unique stage of human thymocyte development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Isoform-specific associations of CD45 with accessory molecules in human T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

1 reference

7 January 2021

Role of CD4+CD45RA+ T cells in the development of autoimmune diabetes in the non-obese diabetic (NOD) mouse.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Selective enrichment of Th1 CD45RBlow CD4+ T cells in autoimmune infiltrates in experimental allergic encephalomyelitis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Regulation of transcription by MAP kinase cascades

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Purification of a murine protein-tyrosine/threonine kinase that phosphorylates and activates the Erk-1 gene product: relationship to the fission yeast byr1 gene product

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The stress-activated protein kinase subfamily of c-Jun kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Ceramide activates the stress-activated protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The Ras-JNK pathway is involved in shear-induced gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in gamma radiation-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

MLK-3 activates the SAPK/JNK and p38/RK pathways via SEK1 and MKK3/6

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Mitogen-activated protein kinase cascades and regulation of gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Stress-signalling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Cellular stresses and cytokines activate multiple mitogen-activated-protein kinase kinase homologues in PC12 and KB cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Activation of Pyk2 by stress signals and coupling with JNK signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Activation of Jun kinase/stress-activated protein kinase by GTPase-deficient mutants of G alpha 12 and G alpha 13.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Ligation of the T cell receptor complex results in activation of the Ras/Raf-1/MEK/MAPK cascade in human T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Contingent genetic regulatory events in T lymphocyte activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

RAFTK, a novel member of the focal adhesion kinase family, is phosphorylated and associates with signaling molecules upon activation of mature T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Blocked Ras activation in anergic CD4+ T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Blocked Signal Transduction to the ERK and JNK Protein Kinases in Anergic CD4+ T Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

T cell inactivation linked to Ras block

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Signal transduction pathways regulated by mitogen-activated/extracellular response kinase kinase kinase induce cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Primary structure and differential gene expression of three membrane forms of guanylyl cyclase found in the eye of the teleost Oryzias latipes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

JNK, but not MAPK, activation is associated with Fas-mediated apoptosis in human T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Activation of SAPK/JNK by TNF receptor 1 through a noncytotoxic TRAF2-dependent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Lack of a role for Jun kinase and AP-1 in Fas-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The MAP kinase pathway controls differentiation from double-negative to double-positive thymocyte.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Activated Ras signals differentiation and expansion of CD4+8+ thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Selective requirement for MAP kinase activation in thymocyte differentiation.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Positive and negative selection invoke distinct signaling pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Raf regulates positive selection

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

NF-kappa B: ten years after

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Multiple Bcl-2 family members demonstrate selective dimerizations with Bax

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

A novel form of Epstein-Barr virus latency in normal B cells in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

How MAP kinases are regulated

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Activation of Raf by ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

1 reference

7 January 2021

Bcl-2 associates with the ras-related protein R-ras p23

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Identification of a novel regulatory domain in Bcl-X(L) and Bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Antiapoptosis potential of bcl-2 oncogene by dephosphorylation.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Inactivation of Bcl-2 by phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Structure-function comparisons of the proapoptotic protein Bax in yeast and mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Suppression of signalling through transcription factor NF-AT by interactions between calcineurin and Bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Interaction and regulation of subcellular localization of CED-4 by CED-9

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Interaction between the C. elegans cell-death regulators CED-9 and CED-4.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Controlling cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Akt signaling: linking membrane events to life and death decisions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Involvement of Cyclophilin D in the Activation of A mitochondrial Pore by Ca2+ and Oxidant Stress

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

PI3K: downstream AKTion blocks apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

p110δ, a novel phosphoinositide 3-kinase in leukocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

R-Ras can activate the phosphoinositide 3-kinase but not the MAP kinase arm of the Ras effector pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor Fc(gamma)RIIB.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

p150Ship, a signal transduction molecule with inositol polyphosphate-5-phosphatase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Two tandem binding sites for sterol regulatory element binding proteins are required for sterol regulation of fatty-acid synthase promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The negative signaling molecule SH2 domain-containing inositol-polyphosphate 5-phosphatase (SHIP) binds to the tyrosine-phosphorylated beta subunit of the high affinity IgE receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Molecular cloning, mapping to human chromosome 1 q21-q23, and cell binding characteristics of Spalpha, a new member of the scavenger receptor cysteine-rich (SRCR) family of proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Mechanism of activation of protein kinase B by insulin and IGF-1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Activation of RAC-protein kinase by heat shock and hyperosmolarity stress through a pathway independent of phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

A lymphotoxin-beta-specific receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The role of APO-1-mediated apoptosis in the immune system

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

A death-domain-containing receptor that mediates apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The receptor for the cytotoxic ligand TRAIL

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

ATAR, a novel tumor necrosis factor receptor family member, signals through TRAF2 and TRAF5

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

CD27: marker and mediator of T-cell activation?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

A receptor induced by lymphocyte activation (ILA): a new member of the human nerve-growth-factor/tumor-necrosis-factor receptor family

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Molecular and biological characterization of human 4-1BB and its ligand

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The p75 neurotrophin receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Osteoprotegerin: a novel secreted protein involved in the regulation of bone density

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Unraveling function in the TNF ligand and receptor families

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Tumor necrosis factor receptor superfamily members and their ligands

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Promotion and inhibition of activation-induced apoptosis in T-cell hybridomas by oncogenes and related signals

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Tumor necrosis factor alpha is an autocrine growth factor for normal human B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Constitutive synthesis of tumor necrosis factor in the thymus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The onset of Fas expression parallels the acquisition of CD8 and CD4 in fetal and adult alpha beta thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Differential expression of APO-1 on human thymocytes: Implications for negative selection?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Transgenic T cell receptor interactions in the lymphoproliferative and autoimmune syndromes of lpr and gld mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Cytotoxicity of fresh NK1.1+ T cell receptor alpha/beta+ thymocytes against a CD4+8+ thymocyte population associated with intact Fas antigen expression on the target

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Selective apoptosis of CD4+CD8+ thymocytes by the anti-Fas antibody

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Kinetics of Fas-induced apoptosis in thymic organ culture.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Activation interferes with the APO-1 pathway in mature human T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Fas transduces activation signals in normal human T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

CD30, Th2 cytokines and HIV infection: a complex and fascinating link

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

CD30 ligand is expressed on resting normal and malignant human B lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Regulation of murine B cell growth and differentiation by CD30 ligand

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

A novel domain within the 55 kd TNF receptor signals cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Modeled structure of the 75-kDa neurotrophin receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

A region of the 75 kDa neurotrophin receptor homologous to the death domains of TNFR‐I and Fas

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

RAIDD is a new 'death' adaptor molecule

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

A potential mechanism of "cross-talk" between the p55 tumor necrosis factor receptor and Fas/APO1: proteins binding to the death domains of the two receptors also bind to each other

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Involvement of an ICE-like protease in Fas-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Bcl-2, Bcl-XL and adenovirus protein E1B19kD are functionally equivalent in their ability to inhibit cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

FAP-1: a protein tyrosine phosphatase that associates with Fas

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Fas and tumor necrosis factor receptor-mediated cell death: similarities and distinctions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

CD30 ligation induces nuclear factor‐ϰB activation in human T cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Anatomy of TRAF2. Distinct domains for nuclear factor-kappaB activation and association with tumor necrosis factor signaling proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Ceramide signalling and the immune response

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Signal transduction through lipid second messengers

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Ceramide: a signal for apoptosis or mitogenesis?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Characterization of a ceramide-activated protein kinase: stimulation by tumor necrosis factor alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Stress-induced apoptosis and the sphingomyelin pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

CD28 signals through acidic sphingomyelinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Sphingomyelin breakdown and cell fate

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Tumor Necrosis Factor-α Activates the Sphingomyelin Signal Transduction Pathway in a Cell-Free System

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

A novel cytoplasmic domain of the p55 tumor necrosis factor receptor initiates the neutral sphingomyelinase pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Apoptosis in human adenocarcinoma HT29 cells induced by exposure to hypoxia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Kinase suppressor of Ras is ceramide-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Direct Effect of Ceramide on the Mitochondrial Electron Transport Chain Leads to Generation of Reactive Oxygen Species

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liver

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Lymphocyte ontogeny and activation in gene targeted mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Cell-free apoptosis in Xenopus egg extracts: inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Energy supply and the shape of death in neurons and lymphoid cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Bcl-2 and Hsp27 act at different levels to suppress programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Oxidative stress, thiol reagents, and membrane potential modulate the mitochondrial permeability transition by affecting nucleotide binding to the adenine nucleotide translocase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Interactions of cyclophilin with the mitochondrial inner membrane and regulation of the permeability transition pore, and cyclosporin A-sensitive channel.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The biochemistry of programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

The pharmacology of T cell apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Calcium-mediated cell injury and cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Temporal changes in chromatin, intracellular calcium, and poly(ADP-ribose) polymerase during Sindbis virus-induced apoptosis of neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960558-1

7 January 2021

10.1016/S0065-2776(08)60558-1

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