Distinct regulation of hypothalamic and brown/beige adipose tissue activities in human obesity. (Q41725895)

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8 March 2020

title

Distinct regulation of hypothalamic and brown/beige adipose tissue activities in human obesity (English)

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16

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Franco Folli

4

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A J Tincani

11

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Bruno Geloneze

14

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8 March 2020

author name string

B Rachid

1

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S van de Sande-Lee

2

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S Rodovalho

3

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G C Beltramini

5

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J Morari

6

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B J Amorim

7

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T Pedro

8

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A F Ramalho

9

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B Bombassaro

10

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E Chaim

12

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J C Pareja

13

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C D Ramos

15

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M J A Saad

17

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L A Velloso

18

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language of work or name

English

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publication date

21 May 2015

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International Journal of Obesity

8 March 2020

published in

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volume

39

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page(s)

1515-1522

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issue

10

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https://scigraph.springernature.com/pub.10.1038/ijo.2015.94

8 March 2020

exact match

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Deletion of tumor necrosis factor-alpha receptor 1 (TNFR1) protects against diet-induced obesity by means of increased thermogenesis

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Decreased brown fat markedly enhances susceptibility to diet-induced obesity, diabetes, and hyperlipidemia.

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Functional brown adipose tissue in healthy adults

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Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human

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A classical brown adipose tissue mRNA signature partly overlaps with brite in the supraclavicular region of adult humans

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Ectopic brown adipose tissue in muscle provides a mechanism for differences in risk of metabolic syndrome in mice

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Leptin-receptor-expressing neurons in the dorsomedial hypothalamus and median preoptic area regulate sympathetic brown adipose tissue circuits

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Systemic β-adrenergic stimulation of thermogenesis is not accompanied by brown adipose tissue activity in humans

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Cold but not sympathomimetics activates human brown adipose tissue in vivo

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Inhibition of hypothalamic inflammation reverses diet-induced insulin resistance in the liver.

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Identifiers

DOI

10.1038/IJO.2015.94

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25994805%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

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