Foot-and-mouth disease virus leader proteinase: structural insights into the mechanism of intermolecular cleavage (Q41732169)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25240326%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

Foot-and-mouth disease virus leader proteinase: structural insights into the mechanism of intermolecular cleavage (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25240326%20AND%20SRC:MED&resulttype=core&format=json

foot-and-mouth disease virus

16 February 2020

main subject

foot-and-mouth disease

1 reference

based on heuristic

inferred from title

object named as

Foot-and-mouth disease virus

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25240326%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Tim Skern

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25240326%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

author name string

Jutta Steinberger

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25240326%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Regina Cencic

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25240326%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Luiz Juliano

4

1 reference

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16 February 2020

Maria A Juliano

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25240326%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

language of work or name

English

0 references

publication date

19 September 2014

1 reference

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16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25240326%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

volume

468-470

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25240326%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

page(s)

397-408

1 reference

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The leader proteinase of foot-and-mouth disease virus: structure-function relationships in a proteolytic virulence factor

16 February 2020

cites work

1 reference

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Comparison of self-processing of foot-and-mouth disease virus leader proteinase and porcine reproductive and respiratory syndrome virus leader proteinase nsp1α.

6 June 2018

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Specificity of human rhinovirus 2A(pro) is determined by combined spatial properties of four cleavage site residues

6 June 2018

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6 June 2018

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A conserved domain in the leader proteinase of foot-and-mouth disease virus is required for proper subcellular localization and function.

6 June 2018

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Investigating the substrate specificity and oligomerisation of the leader protease of foot and mouth disease virus using NMR

6 June 2018

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Degradation of nuclear factor kappa B during foot-and-mouth disease virus infection

6 June 2018

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MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

6 June 2018

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Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions

6 June 2018

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Refinement of macromolecular structures by the maximum-likelihood method

6 June 2018

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Crystal structure of NS-134 in complex with bovine cathepsin B: a two-headed epoxysuccinyl inhibitor extends along the entire active-site cleft.

6 June 2018

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Cleavage of eukaryotic translation initiation factor 4GII within foot-and-mouth disease virus-infected cells: identification of the L-protease cleavage site in vitro

6 June 2018

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Electrostatics of nanosystems: application to microtubules and the ribosome

6 June 2018

1 reference

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Structural and biochemical features distinguish the foot-and-mouth disease virus leader proteinase from other papain-like enzymes

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4220004

eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

6 June 2018

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The structure of the 2A proteinase from a common cold virus: a proteinase responsible for the shut-off of host-cell protein synthesis

6 June 2018

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Structure of the foot-and-mouth disease virus leader protease: a papain-like fold adapted for self-processing and eIF4G recognition

6 June 2018

1 reference

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Interaction of the baculovirus anti-apoptotic protein p35 with caspases. Specificity, kinetics, and characterization of the caspase/p35 complex.

6 June 2018

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Revised definition of substrate binding sites of papain-like cysteine proteases

6 June 2018

1 reference

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Foot-and-mouth disease virus leader proteinase: purification of the Lb form and determination of its cleavage site on eIF-4 gamma

6 June 2018

1 reference

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Functional analysis of the two alternative translation initiation sites of foot-and-mouth disease virus

6 June 2018

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Crystal structure of cathepsin B inhibited with CA030 at 2.0-A resolution: A basis for the design of specific epoxysuccinyl inhibitors

6 June 2018

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Mapping of functional domains in eukaryotic protein synthesis initiation factor 4G (eIF4G) with picornaviral proteases. Implications for cap-dependent and cap-independent translational initiation

6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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Leader protein of foot-and-mouth disease virus is required for cleavage of the p220 component of the cap-binding protein complex

6 June 2018

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Modification of the leader protein (Lb) of foot-and-mouth disease virus

6 June 2018

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6 June 2018

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Hydrolytic properties and substrate specificity of the foot-and-mouth disease leader protease

6 June 2018

1 reference

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Residue L143 of the foot-and-mouth disease virus leader proteinase is a determinant of cleavage specificity

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4220004

The binding of foot-and-mouth disease virus leader proteinase to eIF4GI involves conserved ionic interactions

18 August 2018

1 reference

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Foot-and-mouth disease virus leader proteinase: involvement of C-terminal residues in self-processing and cleavage of eIF4GI.

18 August 2018

1 reference

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Alignment/phylogeny of the papain superfamily of cysteine proteases.

18 August 2018

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A method to produce microseed stock for use in the crystallization of biological macromolecules

7 January 2021

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Foot and mouth disease leader protease (Lbpro): Investigation of prime side specificity allows the synthesis of a potent inhibitor

7 January 2021

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Binding mode of CA074, a specific irreversible inhibitor, to bovine cathepsin B as determined by X-ray crystal analysis of the complex

7 January 2021

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Inhibition of HeLa cell protein synthesis following poliovirus infection correlates with the proteolysis of a 220,000-dalton polypeptide associated with eucaryotic initiation factor 3 and a cap binding protein complex

7 January 2021

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25240326

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.VIROL.2014.08.023

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25240326%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25240326%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

PubMed publication ID

25240326

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25240326%20AND%20SRC:MED&resulttype=core&format=json