Regionally selective changes in brain lysosomes occur in the transition from young adulthood to middle age in rats (Q41734491)

8 October 2017

Regionally selective changes in brain lysosomes occur in the transition from young adulthood to middle age in rats (English)

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8 October 2017

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Bi X

1

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8 October 2017

Yong AP

2

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8 October 2017

Zhou J

3

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8 October 2017

Gall CM

4

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8 October 2017

Lynch G

5

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8 October 2017

language of work or name

English

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publication date

1 January 2000

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8 October 2017

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8 October 2017

97

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8 October 2017

2

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8 October 2017

395-404

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Induction of beta-amyloid-containing polypeptides in hippocampus: evidence for a concomitant loss of synaptic proteins and interactions with an excitotoxin

8 October 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

The distribution of cathepsin D activity in adult and aging human brain regions.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Cytosolic proteolysis of tau by cathepsin D in hippocampus following suppression of cathepsins B and L.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Selective suppression of cathepsin L results from elevations in lysosomal pH and is followed by proteolysis of tau protein

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Suppression of cathepsins B and L causes a proliferation of lysosomes and the formation of meganeurites in hippocampus.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Lysosomal protease inhibitors induce meganeurites and tangle-like structures in entorhinohippocampal regions vulnerable to Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Unilateral injury to the adult rat optic nerve causes multiple cellular responses in the contralateral site

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Neuropathological stageing of Alzheimer-related changes

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Pigmentoarchitectonic pathology of the isocortex in juvenile neuronal ceroid-lipofuscinosis: Axonal enlargements in layer IIIab and cell loss in layer V

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Quantitative decrease in synaptophysin message expression and increase in cathepsin D message expression in Alzheimer disease neurons containing neurofibrillary tangles.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Increased neuronal endocytosis and protease delivery to early endosomes in sporadic Alzheimer's disease: neuropathologic evidence for a mechanism of increased beta-amyloidogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Properties of the endosomal-lysosomal system in the human central nervous system: disturbances mark most neurons in populations at risk to degenerate in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Lysosomal hydrolases of different classes are abnormally distributed in brains of patients with Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Cathepsin D displays in vitro beta-secretase-like specificity.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Isolation of procathepsin D from mature cathepsin D by pepstatin affinity chromatography. Autocatalytic proteolysis of the zymogen form of the enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Participation of intracellular cysteine proteinases, in particular cathepsin B, in degradation of collagen in periosteal tissue explants

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Glial cells in degenerating and regenerating optic nerve of the adult rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Processing of the Pre‐β‐amyloid Protein by Cathepsin d is Enhanced by a Familial Alzheimer's Disease Mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Normal Processing of the Alzheimer's Disease Amyloid β Protein Precursor Generates Potentially Amyloidogenic Carboxyl‐Terminal Derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Microglia as mediators of inflammatory and degenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Lysosomal enzyme precursors in human fibroblasts. Activation of cathepsin D precursor in vitro and activity of beta-hexosaminidase A precursor towards ganglioside GM2.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Beta-amyloid increases cathepsin D levels in hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Regional synaptic pathology in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Abnormal distribution of cathepsin proteinases and endogenous inhibitors (cystatins) in the hippocampus of patients with Alzheimer's disease, parkinsonism-dementia complex on Guam, and senile dementia and in the aged.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Protease inhibition causes some manifestations of aging and Alzheimer's disease in rodent and primate brain

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Inhibitors of lysosomal enzymes: accumulation of lipofuscin-like dense bodies in the brain

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Increase in cathepsin D activity in rat brain in aging

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Degradation of tau by lysosomal enzyme cathepsin D: implication for Alzheimer neurofibrillary degeneration.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Tumor progression and angiogenesis: cathepsin B & Co.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Hippocampal aging in rats: A morphometric study of multiple variables in semithin sections

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Neurofibrillary tangles in Niemann-Pick disease type C

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

A possible role for cathepsins D, E, and B in the processing of beta-amyloid precursor protein in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

GABAergic neuroaxonal dystrophy and other cytopathological alterations in feline Niemann-Pick disease type C.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Synaptic density in the arcuate nucleus of female rats approaching middle age.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Life and death of neurons in the aging brain

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Lysosome instability in aged rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Increased expression of cathepsins E and D in neurons of the aged rat brain and their colocalization with lipofuscin and carboxy-terminal fragments of Alzheimer amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Pick's disease: hyperphosphorylated tau protein segregates to the somatoaxonal compartment.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Fine structure of meganeurites and secondary growth processes in feline GM1-gangliosidosis

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Distortion of neuronal geometry and formation of aberrant synapses in neuronal storage disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Effects of cysteine protease inhibitors on rabbit cathepsin D maturation

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Fine structure of the Pick and Hirano bodies in a case of Pick's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Tyrosine hydroxylase mRNA is increased in old age and norepinephrine uptake transporter mRNA is decreased in middle age in locus coeruleus of Brown-Norway rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Neuropathology of preclinical and clinical late-onset Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Distribution of ectopic neurite growth and other geometrical distortions of CNS neurons in feline GM2 gangliosidosis

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Differential activation of microglia after experimental spinal cord injury.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

Lysosomal dysfunction results in lamina-specific meganeurite formation but not apoptosis in frontal cortex

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2800%2900021-X

7 January 2021

10.1016/S0306-4522(00)00021-X

Identifiers

DOI

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8 October 2017

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