Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis. (Q53920238)

22 May 2018

title

Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis. (English)

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22 May 2018

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Maechler P

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22 May 2018

Wollheim CB

series ordinal

2

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22 May 2018

language of work or name

English

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publication date

1 December 1999

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22 May 2018

published in

Nature

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22 May 2018

volume

402

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22 May 2018

page(s)

685-689

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22 May 2018

issue

6762

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22 May 2018

https://scigraph.springernature.com/pub.10.1038/45280

exact match

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cites work

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Stimulus-secretion coupling in pancreatic beta cells.

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Molecular mechanisms and regulation of insulin exocytosis as a paradigm of endocrine secretion

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Evidence that glucose can control insulin release independently from its action on ATP-sensitive K+ channels in mouse B cells

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Dual Functional Role of Membrane Depolarization/Ca2+ Influx in Rat Pancreatic B-Cell

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Mitochondrial activation directly triggers the exocytosis of insulin in permeabilized pancreatic beta-cells.

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Desensitization of mitochondrial Ca2+ and insulin secretion responses in the beta cell

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Glucose-stimulated insulin secretion correlates with changes in mitochondrial and cytosolic Ca2+ in aequorin-expressing INS-1 cells

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The internal pH and membrane potential of the insulin-secretory granule

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Conversion of proinsulin to insulin occurs coordinately with acidification of maturing secretory vesicles

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Currents through the fusion pore that forms during exocytosis of a secretory vesicle

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7 January 2021

Glutamate transport and storage in synaptic vesicles.

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7 January 2021

Synthesis of ATP by an artificially imposed electrochemical proton gradient in chromaffin granule ghosts

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Ca2+ depletion from granules inhibits exocytosis. A study with insulin-secreting cells

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ATP-dependent and ATP-independent pathways of exocytosis revealed by interchanging glutamate and chloride as the major anion in permeabilized mast cells

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Gi regulation of secretory vesicle swelling examined by atomic force microscopy

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Increased tricarboxylic acid cycle flux in rat brain during forepaw stimulation detected with 1H[13C]NMR.

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Hyperinsulinism and hyperammonemia in infants with regulatory mutations of the glutamate dehydrogenase gene

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Two soluble forms of glutamate dehydrogenase isoproteins from bovine brain

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7 January 2021

Identifiers

DOI

10.1038/45280

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22 May 2018

Dimensions Publication ID

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22 May 2018