Caspases: key mediators of apoptosis (Q41760384)

9 October 2017

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title

Caspases: key mediators of apoptosis (English)

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9 October 2017

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Thornberry NA

1

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9 October 2017

publication date

1 May 1998

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9 October 2017

published in

Chemistry and Biology

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9 October 2017

volume

5

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9 October 2017

issue

5

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9 October 2017

page(s)

R97-103

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Mechanisms and Functions of Cell Death

9 October 2017

cites work

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The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

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7 January 2021

Activation of interleukin-1 beta by a co-induced protease

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A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

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Molecular cloning of the interleukin-1 beta converting enzyme

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Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

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Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

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Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

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7 January 2021

Caspases: killer proteases

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Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

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7 January 2021

Structure and mechanism of interleukin-1 beta converting enzyme

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Crystal structure of the cysteine protease interleukin-1 beta-converting enzyme: a (p20/p10)2 homodimer

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7 January 2021

The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis

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7 January 2021

A combinatorial approach for determining protease specificities: application to interleukin-1beta converting enzyme (ICE)

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7 January 2021

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

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7 January 2021

Peptidyl (acyloxy)methyl ketones and the quiescent affinity label concept: the departing group as a variable structural element in the design of inactivators of cysteine proteinases

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7 January 2021

Inactivation of interleukin-1 beta converting enzyme by peptide (acyloxy)methyl ketones

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7 January 2021

First examples of peptidomimetic inhibitors of interleukin-1 beta converting enzyme

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7 January 2021

Pyridazinodiazepines as a high-affinity, P2-P3 peptidomimetic class of interleukin-1 beta-converting enzyme inhibitor

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7 January 2021

Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme

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7 January 2021

Target protease specificity of the viral serpin CrmA. Analysis of five caspases

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7 January 2021

Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35.

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7 January 2021

X-linked IAP is a direct inhibitor of cell-death proteases

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7 January 2021

The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy

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7 January 2021

10.1016/S1074-5521(98)90615-9

Identifiers

DOI

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9 October 2017

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