Accelerated loss of islet beta cells in sucrose-fed Goto-Kakizaki rats, a genetic model of non-insulin-dependent diabetes mellitus (Q41810412)

12 October 2017

Accelerated loss of islet beta cells in sucrose-fed Goto-Kakizaki rats, a genetic model of non-insulin-dependent diabetes mellitus (English)

1 reference

12 October 2017

1 reference

M Koyama

1

1 reference

12 October 2017

R Wada

2

1 reference

12 October 2017

H Sakuraba

3

1 reference

12 October 2017

H Mizukami

4

1 reference

12 October 2017

S Yagihashi

5

1 reference

12 October 2017

language of work or name

English

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publication date

1 August 1998

1 reference

The American Journal of Pathology

12 October 2017

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12 October 2017

153

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12 October 2017

2

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12 October 2017

537-545

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Impaired development of pancreatic beta-cell mass is a primary event during the progression to diabetes in the GK rat.

12 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852987

The proto-oncogene Bcl-2 and its role in regulating apoptosis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852987

Reducing sugars trigger oxidative modification and apoptosis in pancreatic beta-cells by provoking oxidative stress through the glycation reaction

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852987

Long-term effects of aminoguanidine on insulin release and biosynthesis: evidence that the formation of advanced glycosylation end products inhibits B cell function

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852987

Impaired insulin secretion and excessive hepatic glucose production are both early events in the diabetic GK rat.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852987

8-hydroxy-2'-deoxyguanosine is increased in epidermal cells of hairless mice after chronic ultraviolet B exposure

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852987

Cytokine-induced apoptotic cell death in a mouse pancreatic beta-cell line: inhibition by Bcl-2.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852987

Beta-cell mass depletion precedes the onset of hyperglycaemia in the GK rat, a genetic model of non-insulin-dependent diabetes mellitus.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852987

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852987

BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852987

Potent inhibitory effects of transplantable rat glucagonomas and insulinomas on the respective endogenous islet cells are associated with pancreatic apoptosis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852987

Minimal chronic hyperglycemia is a critical determinant of impaired insulin secretion after an incomplete pancreatectomy

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852987

Islet amyloid, increased A-cells, reduced B-cells and exocrine fibrosis: quantitative changes in the pancreas in type 2 diabetes.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852987

Hyperglycemia-induced B cell toxicity. The fate of pancreatic islets transplanted into diabetic mice is dependent on their genetic background

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852987

Natural history of beta-cell dysfunction in NIDDM.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852987

Beta-cell insensitivity to glucose in the GK rat, a spontaneous nonobese model for type II diabetes

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852987

BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852987

Differential volumetry of A,B and D cells in the pancreatic islets of diabetic and nondiabetic subjects

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852987

Genetic analysis of non-insulin dependent diabetes mellitus in the GK rat.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1852987

Cellular composition of the human diabetic pancreas

18 August 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965596-4

Quantitation of Endocrine Cell Content in the Pancreas of Nondiabetic and Diabetic Humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965596-4

Abnormal insulin secretion and glucose metabolism in pancreatic islets from the spontaneously diabetic GK rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965596-4

Preserved beta-cell density in the endocrine pancreas of young, spontaneously diabetic Goto-Kakizaki (GK) rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965596-4

Poor capacity for proliferation of pancreatic beta-cells in Otsuka-Long-Evans-Tokushima Fatty rat: a model of spontaneous NIDDM

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965596-4

Morphometric evidence for a striking B-cell reduction at the clinical onset of type 1 diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965596-4

Effects of chronically elevated glucose levels on the functional properties of rat pancreatic beta-cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965596-4

Possible role of glycogen accumulation in B-cell glucotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965596-4

Lack of deterioration of insulin action with aging in the GK rat: a contrasted adaptation as compared with nondiabetic rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965596-4

Weakened cellular scavenging activity against oxidative stress in diabetes mellitus: regulation of glutathione synthesis and efflux

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965596-4

Chromosomal mapping of genetic loci associated with non-insulin dependent diabetes in the GK rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965596-4

10.1016/S0002-9440(10)65596-4

7 January 2021

Identifiers

DOI

1 reference

release_4v5oup3cbnb6zde7nsowd2n6zm

12 October 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/4v5oup3cbnb6zde7nsowd2n6zm

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

12 October 2017

1 reference